Structure-activity relationships of retinoids in developmental toxicology. IV. Planar Cisoid conformational restriction.

[1]  G. Frenking,et al.  Effect of structural modifications in the C7-C11 region of the retinoid skeleton on biological activity in a series of aromatic retinoids. , 1989, Journal of medicinal chemistry.

[2]  C C Willhite,et al.  Dose response and structure-activity considerations in retinoid-induced dysmorphogenesis. , 1989, Critical reviews in toxicology.

[3]  M. Wiley,et al.  A comparative study of the effects of retinoic acid given during the critical period for inducing spina bifida in mice and hamsters. , 1988, Teratology.

[4]  W. B. Howard,et al.  Structure-toxicity relationships of the tetramethylated tetralin and indane analogs of retinoic acid. , 1987, Teratology.

[5]  C. Willhite,et al.  Comparative teratogenic activity of cancer chemopreventive retinoidal benzoic acid congeners (arotinoids). , 1987, Journal of the National Cancer Institute.

[6]  J. Tousignant,et al.  Treatment of cutaneous T-cell lymphoma with the arotinoid Ro 13-6298. , 1987, Journal of the American Academy of Dermatology.

[7]  B. Helpap,et al.  Sirenomelia and anencephaly in one of dizygotic twins. , 1986, Teratology.

[8]  C. Willhite,et al.  Morphogenesis of isotretinoin-induced microcephaly and micrognathia studied by scanning electron microscopy. , 1986, Teratology.

[9]  A. Kistler Structure-activity relationship of retinoids on lobuloalveolar differentiation of cultured mouse mammary glands. , 1986, Carcinogenesis.

[10]  Y. Hashimoto,et al.  Differentiation inducers of human promyelocytic leukemia cells HL-60. Phenylcarbamoylbenzoic acids and polyene amides. , 1986, Chemical & pharmaceutical bulletin.

[11]  N. Lowe,et al.  A comparative study of the induction of epidermal hyperplasia by natural and synthetic retinoids. , 1986, The Journal of pharmacology and experimental therapeutics.

[12]  W. B. Howard,et al.  Toxicity of Retinoids in Humans and Animals , 1986 .

[13]  Hill Rm,et al.  Isotretinoin-induced craniofacial malformations in humans and hamsters. , 1986 .

[14]  D. Hilbelink,et al.  Sirenomelia: analysis in the cadmium- and lead-treated golden hamster. , 1986, Teratogenesis, carcinogenesis, and mutagenesis.

[15]  P. Fernhoff,et al.  Retinoic acid embryopathy. , 1985, The New England journal of medicine.

[16]  M. Sporn,et al.  Retinoids and Differentiation of Cells of Mesenchymal Origin , 1985 .

[17]  W. Bollag New Retinoids with Potential Use in Humans , 1985 .

[18]  E. M. Holt,et al.  Synthesis and characterization of selected heteroarotinoids. Pharmacological activity as assessed in vitamin A deficient hamster tracheal organ cultures. Single-crystal X-ray diffraction analysis of 4,4-dimethylthiochroman-6-yl methyl ketone 1,1-dioxide and ethyl (E)-p-[2-(4,4-dimethylthiochroman-6- , 1985, Journal of medicinal chemistry.

[19]  N. van Regemorter,et al.  A case of partial sirenomelia and possible vitamin A teratogenesis , 1985, Prenatal diagnosis.

[20]  J. Gruber,et al.  Conformationally restricted retinoids. , 1984, Journal of medicinal chemistry.

[21]  W. B. Howard,et al.  Structure-Activity Relationships of Retinoids in Developmental Toxicology , 1984 .

[22]  N. Lowe,et al.  Histologic changes in the skin of the rhino mouse (hrrhhrrh) induced by retinoids. , 1984, The Journal of investigative dermatology.

[23]  G M Schoofs,et al.  A probit analysis program for the personal computer , 1984, Journal of applied toxicology : JAT.

[24]  C. Willhite,et al.  Amelioration of embryotoxicity by structural modification of the terminal group of cancer chemopreventive retinoids. , 1984, Journal of the National Cancer Institute.

[25]  P. Fritsch,et al.  Response of Psoriatic Arthropathy to Arotinoid (Ro 13-6298): A Pilot Study , 1984 .

[26]  M. Dawson,et al.  Relationship between binding affinities to cellular retinoic acid-binding protein and biological potency of a new series of retinoids. , 1984, Cancer research.

[27]  G. Mahrle,et al.  Chemotherapie kutaner T-Zell-Lymphome mit Arotinoid , 1983, Deutsche medizinische Wochenschrift.

[28]  W. Kueng,et al.  Sulfur-containing arotinoids, a new class of retinoids , 1984 .

[29]  M. Dawson,et al.  Synthesis and pharmacological activity of 6-[(E)-2-(2,6,6-trimethyl-1-cyclohexen-1-yl)ethen-1-yl]- and 6-(1,2,3,4-tetrahydro-1,1,4,4-tetramethyl-6-naphthyl)-2-naphthalenecarboxylic acids. , 1983, Journal of medicinal chemistry.

[30]  M. Sporn,et al.  Structure-activity relationships of a new series of retinoidal benzoic acid derivatives as measured by induction of differentiation of murine F9 teratocarcinoma cells and human HL-60 promyelocytic leukemia cells. , 1983, Cancer research.

[31]  C. Orfanos,et al.  Antipsoriatic activity of a new synthetic retinoid. The arotinoid RO 13-6298. , 1983, Archives of dermatology.

[32]  M. Dawson,et al.  Aromatic retinoic acid analogues. 2. Synthesis and pharmacological activity. , 1983, Journal of medicinal chemistry.

[33]  M. Taketo,et al.  Effects of arotinoids upon murine embryonal carcinoma cells. , 1983, Cancer research.

[34]  M. Sporn,et al.  Structure-activity relationships of retinoids in hamster tracheal organ culture. , 1980, Cancer research.

[35]  P. Loeliger,et al.  AROTINOIDS, A NEW CLASS OF HIGHLY ACTIVE RETINOIDS , 1980 .

[36]  E. Giavini,et al.  The extent of fetal ossification as an index of delayed development in teratogenic studies on the rat. , 1979, Teratology.