Bufalin prevents the migration and invasion of T24 bladder carcinoma cells through the inactivation of matrix metalloproteinases and modulation of tight junctions.
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[1] Jai-Sing Yang,et al. Bufalin‐inhibited migration and invasion in human osteosarcoma U‐2 OS cells is carried out by suppression of the matrix metalloproteinase‐2, ERK, and JNK signaling pathways , 2014, Environmental toxicology.
[2] T. Gress,et al. Claudin-4 as therapeutic target in cancer. , 2012, Archives of biochemistry and biophysics.
[3] Seok-Jun Kim,et al. Galectin-3 increases the motility of mouse melanoma cells by regulating matrix metalloproteinase-1 expression , 2012, Experimental & Molecular Medicine.
[4] In-Chul Lee,et al. Anti-inflammatory functions of purpurogallin in LPS-activated human endothelial cells. , 2012, BMB reports.
[5] N. Takai,et al. Bufalin, a traditional oriental medicine, induces apoptosis in human cancer cells. , 2012, Asian Pacific journal of cancer prevention : APJCP.
[6] V. Mechírová,et al. Matrix Metalloproteinases and Their Role in Oncogenesis: A Review , 2012, Oncology Research and Treatment.
[7] Yung-Hyun Choi,et al. Bufalin induces apoptosis through activation of both the intrinsic and extrinsic pathways in human bladder cancer cells. , 2011, Oncology reports.
[8] P. Riesz,et al. 7117 POSTER Claudins and Ki-67 – Potential Markers to Differentiate Low and High Grade Transitional Cell Carcinomas of the Urinary Bladder , 2011 .
[9] S. Ergün,et al. Matrix metalloproteinases and their clinical relevance in urinary bladder cancer , 2011, Nature Reviews Urology.
[10] N. Ohashi,et al. Occludin is regulated by epidermal growth factor receptor activation in brain endothelial cells and brains of mice with acute liver failure , 2011, Hepatology.
[11] K. Yagi,et al. Claudin as a target for drug development. , 2011, Current medicinal chemistry.
[12] Wei Tang,et al. Antitumor activity of extracts and compounds from the skin of the toad Bufo bufo gargarizans Cantor. , 2011, International immunopharmacology.
[13] Yung-Hyun Choi,et al. Anti-invasive activities of anthocyanins through modulation of tight junctions and suppression of matrix metalloproteinase activities in HCT-116 human colon carcinoma cells. , 2011, Oncology reports.
[14] Cheng Jiang,et al. Bufadienolide compounds sensitize human breast cancer cells to TRAIL-induced apoptosis via inhibition of STAT3/Mcl-1 pathway , 2011, Apoptosis.
[15] Ying Zhang,et al. Effects of bufalin on the proliferation of human lung cancer cells and its molecular mechanisms of action , 2010, Cytotechnology.
[16] E. Leygue,et al. Claudin 1 in Breast Tumorigenesis: Revelation of a Possible Novel “Claudin High” Subset of Breast Cancers , 2010, Journal of biomedicine & biotechnology.
[17] Z. Werb,et al. Matrix Metalloproteinases: Regulators of the Tumor Microenvironment , 2010, Cell.
[18] P. Timpson,et al. Quantitative real-time imaging of molecular dynamics during cancer cell invasion and metastasis in vivo , 2009, Cell adhesion & migration.
[19] Y. Yoo,et al. Anti-invasive activity of sanguinarine through modulation of tight junctions and matrix metalloproteinase activities in MDA-MB-231 human breast carcinoma cells. , 2009, Chemico-biological interactions.
[20] W. Zhong,et al. CD147, MMP-1, MMP-2 and MMP-9 Protein Expression as Significant Prognostic Factors in Human Prostate Cancer , 2008, Oncology.
[21] K. Nakanishi,et al. Expression of occludin and claudins 1, 3, 4, and 7 in urothelial carcinoma of the upper urinary tract. , 2008, American journal of clinical pathology.
[22] T. Ueda,et al. Bufalin induces growth inhibition, cell cycle arrest and apoptosis in human endometrial and ovarian cancer cells. , 2008, International journal of molecular medicine.
[23] P. Morin. Claudin Proteins in Ovarian Cancer , 2007, Disease markers.
[24] A. Yu,et al. Claudins and paracellular transport: an update , 2007, Current opinion in nephrology and hypertension.
[25] C. Dinney,et al. Bladder cancer angiogenesis and metastasis—translation from murine model to clinical trial , 2007, Cancer and Metastasis Reviews.
[26] L. Matrisian,et al. The other side of MMPs: Protective roles in tumor progression , 2007, Cancer and Metastasis Reviews.
[27] Wei-wei Su,et al. Bufalin induces apoptosis in human osteosarcoma U-2OS and U-2OS methotrexate300-resistant cell lines , 2007, Acta Pharmacologica Sinica.
[28] F. Hollande,et al. DNA-methylation-dependent alterations of claudin-4 expression in human bladder carcinoma. , 2007, Carcinogenesis.
[29] A. Newby,et al. Matrix metalloproteinases regulate migration, proliferation, and death of vascular smooth muscle cells by degrading matrix and non-matrix substrates. , 2006, Cardiovascular research.
[30] G. Daley,et al. Novel role for PDEF in epithelial cell migration and invasion. , 2005, Cancer research.
[31] P. Morin,et al. Claudin proteins in human cancer: promising new targets for diagnosis and therapy. , 2005, Cancer research.
[32] P. Morin,et al. Claudin-3 and claudin-4 expression in ovarian epithelial cells enhances invasion and is associated with increased matrix metalloproteinase-2 activity. , 2005, Cancer research.
[33] E. Lo,et al. Downregulation of matrix metalloproteinase-9 and attenuation of edema via inhibition of ERK mitogen activated protein kinase in traumatic brain injury. , 2002, Journal of neurotrauma.
[34] Z. Werb,et al. New functions for the matrix metalloproteinases in cancer progression , 2002, Nature Reviews Cancer.
[35] M. Birrer,et al. Alterations in differentiation and apoptosis induced by bufalin in cJun overexpressing U-937 cells. , 1998, International journal of oncology.
[36] R. Dickson,et al. Matrix metalloproteinase inhibitors , 1997, Investigational New Drugs.
[37] Y. Jing,et al. Differentiation of promyelocytic leukemia cells HL-60 induced by daidzein in vitro and in vivo. , 1993, Anticancer research.
[38] T. Yoshida,et al. Bufalin as a potent inducer of differentiation of human myeloid leukemia cells. , 1991, Biochemical and biophysical research communications.
[39] Abderrahman Ouban,et al. Claudins in human cancer: a review. , 2010, Histology and histopathology.
[40] I. Căruntu,et al. Matrix metalloproteinases involvement in pathologic conditions. , 2010, Romanian journal of morphology and embryology = Revue roumaine de morphologie et embryologie.
[41] Kyle J Hewitt,et al. The claudin gene family: expression in normal and neoplastic tissues , 2006, BMC Cancer.
[42] A. Nusrat,et al. Tight junctions and cell-cell interactions. , 2006, Methods in molecular biology.
[43] H. Klocker,et al. Type IV collagenase (matrix metalloproteinase-2 and -9) in prostate cancer , 2004, Prostate Cancer and Prostatic Diseases.
[44] X. Jin,et al. [Studies on the chemical constituents from the skin of Bufo bufo gargarizans Cantor]. , 1992, Yao xue xue bao = Acta pharmaceutica Sinica.
[45] R. Visse,et al. This Review Is Part of a Thematic Series on Matrix Metalloproteinases, Which Includes the following Articles: Matrix Metalloproteinase Inhibition after Myocardial Infarction: a New Approach to Prevent Heart Failure? Matrix Metalloproteinases in Vascular Remodeling and Atherogenesis: the Good, the Ba , 2022 .