Heterogeneous Loss of Connexin43 Protein in Nonischemic Dilated Cardiomyopathy with Ventricular Tachycardia

Connexin43 Expression in DCM. Introduction: Gap junction alterations recently have been implicated in chronic heart failure, but direct evidence between gap junction manifestation in nonischemic dilated cardiomyopathy (DCM) is lacking. The current study examines whether qualitative changes or altered distribution of gap junctional connexin43 (Cx43) are related to global ventricular function and ventricular arrhythmia in DCM.

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