SBGN-ED – working with the Systems Biology Graphical Notation

References [1] N. Le Novère et. al: Systems Biology Graphical Notation. Nature Biotechnology, 27:735-741 (2009). [2] T. Czauderna, C. Klukas, F. Schreiber: Editing, Validating, and Translating of SBGN Maps. Bioinformatics, 26(18):2340-2341 (2010). The Systems Biology Graphical Notation (SBGN) [1] is a standard for the visual representation of biochemical and cellular processes and networks. Three different views (Process Description, Entity Relationship, and Activity Flow) cover several aspects of the biological system in different levels of detail. SBGN helps to communicate biological knowledge more efficient and accurate between different research communities. However, to work efficiently with SBGN, powerful and easy to use tools are necessary. Here we present methods for working with SBGN implemented in SBGN-ED [2], a tool which allows to create all types of SBGN maps from scratch, to validate these maps for syntactical and semantical correctness, to translate maps from the KEGG databases into SBGN, to explore SBGN maps, and to export them into several file and image formats.