Laser-based ion doping is a suitable alternative to dope biologically active ions into colloidal bioglass nanoparticles

We show that pulsed laser doping is a promising technique to dope multiple ions in nBGs without negatively impacting their structure or size and that laser doping of FeSr into nBGs can improve the angiogenic properties of nBGs.

[1]  S. Barcikowski,et al.  Photomechanical Laser Fragmentation of IrO2 Microparticles for the Synthesis of Active and Redox-Sensitive Colloidal Nanoclusters. , 2023, Small.

[2]  M. Vallet‐Regí,et al.  Achievements in Mesoporous Bioactive Glasses for Biomedical Applications , 2022, Pharmaceutics.

[3]  A. Boccaccini,et al.  Zn-Loaded and Calcium Phosphate-Coated Degradable Silica Nanoparticles Can Effectively Promote Osteogenesis in Human Mesenchymal Stem Cells , 2022, Nanomaterials.

[4]  S. Barcikowski,et al.  Co-doping of iron and copper ions in nanosized bioactive glass by reactive laser fragmentation in liquids. , 2022, Journal of biomedical materials research. Part A.

[5]  K. de Groot,et al.  Calcium phosphate and silicate-based nanoparticles: history and emerging trends. , 2022, Tissue engineering. Part A.

[6]  P. Habibović,et al.  Peptide-Modified Nano-Bioactive Glass for Targeted Immobilization of Native VEGF , 2022, ACS applied materials & interfaces.

[7]  S. Barcikowski,et al.  Gradually Fe-doped Co3O4 nanoparticles in 2-propanol and water oxidation catalysis with single laser pulse resolution. , 2022, The Journal of Physical Chemistry C.

[8]  H. Kim,et al.  Iron ions-releasing mesoporous bioactive glass ultrasmall nanoparticles designed as ferroptosis-based bone cancer nanotherapeutics: Ultrasonic-coupled sol–gel synthesis, properties and iron ions release , 2021, Materials Letters.

[9]  J. Kolmas,et al.  The Influence of Strontium on Bone Tissue Metabolism and Its Application in Osteoporosis Treatment , 2021, International journal of molecular sciences.

[10]  A. A. Zadpoor,et al.  Inorganic Agents for Enhanced Angiogenesis of Orthopedic Biomaterials , 2021, Advanced healthcare materials.

[11]  A. Boccaccini,et al.  Multi-Functional Silica-Based Mesoporous Materials for Simultaneous Delivery of Biologically Active Ions and Therapeutic Biomolecules. , 2021, Acta biomaterialia.

[12]  Xi‐Wen Du,et al.  Oxidized Single Nickel Atoms Embedded in Ru Matrix for Highly Efficient Hydrogen Evolution Reaction , 2021 .

[13]  Xi‐Wen Du,et al.  Iridium Oxide Modified with Silver Single Atom for Boosting Oxygen Evolution Reaction in Acidic Media , 2021 .

[14]  X. Chatzistavrou,et al.  Bioactive Glass Nanoparticles for Tissue Regeneration , 2020, ACS omega.

[15]  Tao Yu,et al.  Enhanced angiogenesis of biodegradable iron-doped octacalcium phosphate/poly(lactic-co-glycolic acid) scaffold for potential cancerous bone regeneration , 2019, Applied Materials Today.

[16]  Xi‐Wen Du,et al.  Ruthenium‐Based Single‐Atom Alloy with High Electrocatalytic Activity for Hydrogen Evolution , 2019, Advanced Energy Materials.

[17]  Zhilong Shi,et al.  Development of mesoporous bioactive glass nanoparticles and its use in bone tissue engineering. , 2018, Journal of biomedical materials research. Part B, Applied biomaterials.

[18]  Xiaofeng Chen,et al.  Promoting in vivo early angiogenesis with sub-micrometer strontium-contained bioactive microspheres through modulating macrophage phenotypes. , 2018, Biomaterials.

[19]  Ashok Kumar,et al.  Effects of transition metal ion dopants (Ag, Cu and Fe) on the structural, mechanical and antibacterial properties of bioactive glass , 2018 .

[20]  Julian R. Jones,et al.  In vitro osteogenesis by intracellular uptake of strontium containing bioactive glass nanoparticles. , 2018, Acta biomaterialia.

[21]  Livia Visai,et al.  POLITECNICO DI TORINO Repository ISTITUZIONALE Copper-containing mesoporous bioactive glass nanoparticles as multifunctional agent for bone regeneration / , 2022 .

[22]  I. Cacciotti Bivalent cationic ions doped bioactive glasses: the influence of magnesium, zinc, strontium and copper on the physical and biological properties , 2017, Journal of Materials Science.

[23]  Kai Zheng,et al.  Sol-gel processing of bioactive glass nanoparticles: A review. , 2017, Advances in colloid and interface science.

[24]  M. Catauro,et al.  Chemical, biological, and antibacterial characterization of silica glass containing silver and gold nanoparticles , 2017 .

[25]  E. Tolnai,et al.  Iron overload inhibits osteogenic commitment and differentiation of mesenchymal stem cells via the induction of ferritin. , 2016, Biochimica et biophysica acta.

[26]  S. Barcikowski,et al.  Quantification of mass-specific laser energy input converted into particle properties during picosecond pulsed laser fragmentation of zinc oxide and boron carbide in liquids , 2015 .

[27]  M. Trincavelli,et al.  ♦Copper (II) ions modulate Angiogenin activity in human endothelial cells. , 2015, The international journal of biochemistry & cell biology.

[28]  X. Chen,et al.  Inhibition of osteogenic differentiation of mesenchymal stem cells by copper supplementation , 2014, Cell proliferation.

[29]  Youjia Xu,et al.  Iron Overload Inhibits Osteoblast Biological Activity Through Oxidative Stress , 2013, Biological Trace Element Research.

[30]  Laure Gambardella,et al.  A Computational Tool for Quantitative Analysis of Vascular Networks , 2011, PloS one.

[31]  S. Abramson,et al.  Inhibitory effects of iron on bone morphogenetic protein 2–induced osteoblastogenesis , 2011, Journal of bone and mineral research : the official journal of the American Society for Bone and Mineral Research.

[32]  Aldo R Boccaccini,et al.  A review of the biological response to ionic dissolution products from bioactive glasses and glass-ceramics. , 2011, Biomaterials.

[33]  Gavin Jell,et al.  The effects of strontium-substituted bioactive glasses on osteoblasts and osteoclasts in vitro. , 2010, Biomaterials.

[34]  Derek W. Smith Ionic hydration enthalpies , 1977 .

[35]  L. Sreebny,et al.  Demineralization of Hard Tissues by Organic Chelating Agents at Neutral pH , 1953, Journal of dental research.

[36]  Ashraf F. Ali,et al.  Synthesis, characterization and microbiological response of silver doped bioactive glass nanoparticles , 2012 .

[37]  R. Cabrini,et al.  Osteoconductivity of strontium-doped bioactive glass particles: a histomorphometric study in rats. , 2010, Journal of biomedical materials research. Part A.

[38]  S. Siekierski Ionic Radii: Effect of Shell Radius, Cation Charge and Lone Electron Pair , 1997 .