Enhanced caspase-8 recruitment to and activation at the DISC is critical for sensitisation of human hepatocellular carcinoma cells to TRAIL-induced apoptosis by chemotherapeutic drugs
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W. Stremmel | P. Krammer | A. Krueger | A. Grosse-Wilde | M. Weigand | H. Walczak | H. Stahl | M. Sprick | T. Haas | J. Sykora | T. Ganten | S. Fas | W. Stremmel | A. Grosse‐Wilde
[1] D. Waisman,et al. RNA Interference-mediated Silencing of the S100A10 Gene Attenuates Plasmin Generation and Invasiveness of Colo 222 Colorectal Cancer Cells* , 2004, Journal of Biological Chemistry.
[2] E. Bröcker,et al. Proteasome Inhibition Results in TRAIL Sensitization of Primary Keratinocytes by Removing the Resistance-Mediating Block of Effector Caspase Maturation , 2003, Molecular and Cellular Biology.
[3] H. Wajant,et al. Selective Inhibition of FLICE-like Inhibitory Protein (FLIP) Expression With Small Interfering RNA Oligonucleotides (siRNAs) Is Sufficient to Sensitize Tumor Cells for TRAIL-Induced Apoptosis , 2002 .
[4] G. Cohen,et al. Mechanisms of resistance to TRAIL-induced apoptosis in primary B cell chronic lymphocytic leukaemia , 2002, Oncogene.
[5] A. Grosse-Wilde,et al. Caspase‐10 is recruited to and activated at the native TRAIL and CD95 death‐inducing signalling complexes in a FADD‐dependent manner but can not functionally substitute caspase‐8 , 2002, The EMBO journal.
[6] E. Borden,et al. Identification of X-linked Inhibitor of Apoptosis-associated Factor-1 as an Interferon-stimulated Gene That Augments TRAIL Apo2L-induced Apoptosis* , 2002, The Journal of Biological Chemistry.
[7] Xiaolu Yang,et al. c‐FLIPL is a dual function regulator for caspase‐8 activation and CD95‐mediated apoptosis , 2002, The EMBO journal.
[8] Sunshin Kim,et al. Resistance of mitochondrial DNA-deficient cells to TRAIL: role of Bax in TRAIL-induced apoptosis , 2002, Oncogene.
[9] S. Fulda,et al. Inhibition of TRAIL-induced apoptosis by Bcl-2 overexpression , 2002, Oncogene.
[10] J. Herman,et al. Tumor-specific down-regulation of the tumor necrosis factor-related apoptosis-inducing ligand decoy receptors DcR1 and DcR2 is associated with dense promoter hypermethylation. , 2002, Cancer research.
[11] K. Tyler,et al. TRAIL and inhibitors of apoptosis are opposing determinants for NF-κB-dependent, genotoxin-induced apoptosis of cancer cells , 2002, Oncogene.
[12] H. Shu,et al. The short splice form of Casper/c‐FLIP is a major cellular inhibitor of TRAIL‐induced apoptosis , 2002, FEBS letters.
[13] J. Blenis,et al. Death Receptor Recruitment of Endogenous Caspase-10 and Apoptosis Initiation in the Absence of Caspase-8* , 2001, The Journal of Biological Chemistry.
[14] G. Gores,et al. The Bile Acid Glycochenodeoxycholate Induces TRAIL-Receptor 2/DR5 Expression and Apoptosis* , 2001, The Journal of Biological Chemistry.
[15] P. Hersey,et al. Tumor necrosis factor-related apoptosis-inducing ligand-induced apoptosis of human melanoma is regulated by smac/DIABLO release from mitochondria. , 2001, Cancer research.
[16] G. Cohen,et al. Modulation of Tumor Necrosis Factor Apoptosis-inducing Ligand- induced NF-κB Activation by Inhibition of Apical Caspases* , 2001, The Journal of Biological Chemistry.
[17] Z. Wang,et al. Tumoricidal activity of a novel anti-human DR5 monoclonal antibody without hepatocyte cytotoxicity , 2001, Nature Medicine.
[18] B. Vandenbunder,et al. Rel/NF-κB Transcription Factors Protect against Tumor Necrosis Factor (TNF)-related Apoptosis-inducing Ligand (TRAIL)-induced Apoptosis by Up-regulating the TRAIL Decoy Receptor DcR1* , 2001, The Journal of Biological Chemistry.
[19] Shi-Yong Sun,et al. Evidence that the death receptor DR4 is a DNA damage‐inducible, p53‐regulated gene , 2001, Journal of cellular physiology.
[20] G. Gores,et al. Is TRAIL hepatotoxic? , 2001, Hepatology.
[21] H. Walczak,et al. Biochemistry and function of the DISC. , 2001, Trends in biochemical sciences.
[22] P. Krammer,et al. Cellular FLICE-inhibitory Protein Splice Variants Inhibit Different Steps of Caspase-8 Activation at the CD95 Death-inducing Signaling Complex* , 2001, The Journal of Biological Chemistry.
[23] M. Nau,et al. Synergistic induction of apoptosis by the combination of trail and chemotherapy in chemoresistant ovarian cancer cells. , 2001, Gynecologic oncology.
[24] R. K Srivastava,et al. Intracellular mechanisms of TRAIL: apoptosis through mitochondrial-dependent and -independent pathways , 2001, Oncogene.
[25] C. Belka,et al. Sensitization of resistant lymphoma cells to irradiation-induced apoptosis by the death ligand TRAIL , 2001, Oncogene.
[26] S. S. Strom,et al. Differential hepatocyte toxicity of recombinant Apo2L/TRAIL versions , 2001, Nature Medicine.
[27] Erwin G. Van Meir,et al. Induction and intracellular regulation of tumor necrosis factor-related apoptosis-inducing ligand (TRAIL) mediated apotosis in human malignant glioma cells. , 2001, Cancer research.
[28] L. Corcos,et al. Anticancer agents sensitize tumor cells to tumor necrosis factor-related apoptosis-inducing ligand-mediated caspase-8 activation and apoptosis. , 2001, Cancer research.
[29] K. Bhalla,et al. Antileukemic drugs increase death receptor 5 levels and enhance Apo-2L-induced apoptosis of human acute leukemia cells. , 2000, Blood.
[30] P. Krammer,et al. TCR-Mediated Up-Regulation of c-FLIPshort Correlates with Resistance Toward CD95-Mediated Apoptosis by Blocking Death-Inducing Signaling Complex Activity1 , 2000, The Journal of Immunology.
[31] P. Hersey,et al. TNF-Related Apoptosis-Inducing Ligand-Induced Apoptosis of Melanoma Is Associated with Changes in Mitochondrial Membrane Potential and Perinuclear Clustering of Mitochondria1 , 2000, The Journal of Immunology.
[32] J. Soria,et al. TRAIL-R2 is not correlated with p53 status and is rarely mutated in non-small cell lung cancer. , 2000, Anticancer research.
[33] P. Krammer,et al. CD95's deadly mission in the immune system , 2000, Nature.
[34] P. Hersey,et al. Mechanisms of resistance of normal cells to TRAIL induced apoptosis vary between different cell types , 2000, FEBS letters.
[35] A. Fornace,et al. Death and decoy receptors and p53-mediated apoptosis , 2000, Leukemia.
[36] R. K Srivastava. Intracellular mechanisms of TRAIL and its role in cancer therapy. , 2000, Molecular cell biology research communications : MCBRC.
[37] D. Lawrence,et al. Apo2L/TRAIL-dependent recruitment of endogenous FADD and caspase-8 to death receptors 4 and 5. , 2000, Immunity.
[38] J. Blenis,et al. FADD/MORT1 and caspase-8 are recruited to TRAIL receptors 1 and 2 and are essential for apoptosis mediated by TRAIL receptor 2. , 2000, Immunity.
[39] P. Krammer,et al. Tumor necrosis factor-related apoptosis-inducing ligand retains its apoptosis-inducing capacity on Bcl-2- or Bcl-xL-overexpressing chemotherapy-resistant tumor cells. , 2000, Cancer research.
[40] S. Strom,et al. Apoptosis induced in normal human hepatocytes by tumor necrosis factor-related apoptosis-inducing ligand , 2000, Nature Medicine.
[41] J. Tschopp,et al. TRAIL receptor-2 signals apoptosis through FADD and caspase-8 , 2000, Nature Cell Biology.
[42] W. Cavenee,et al. Increased death receptor 5 expression by chemotherapeutic agents in human gliomas causes synergistic cytotoxicity with tumor necrosis factor-related apoptosis-inducing ligand in vitro and in vivo. , 2000, Cancer research.
[43] E. Bröcker,et al. Regulation of tumor necrosis factor-related apoptosis-inducing ligand sensitivity in primary and transformed human keratinocytes. , 2000, Cancer research.
[44] B. Gliniak,et al. Tumor necrosis factor-related apoptosis-inducing ligand's antitumor activity in vivo is enhanced by the chemotherapeutic agent CPT-11. , 1999, Cancer research.
[45] J. Houghton. Apoptosis and drug response. , 1999, Current opinion in oncology.
[46] D. Lawrence,et al. Safety and antitumor activity of recombinant soluble Apo2 ligand. , 1999, The Journal of clinical investigation.
[47] C. Rauch,et al. Tumoricidal activity of tumor necrosis factor–related apoptosis–inducing ligand in vivo , 1999, Nature Medicine.
[48] Ingo Schmitz,et al. The Role of c-FLIP in Modulation of CD95-induced Apoptosis* , 1999, The Journal of Biological Chemistry.
[49] P. Galle,et al. The role of p53 and the CD95 (APO-1/Fas) death system in chemotherapy-induced apoptosis. , 1999, European cytokine network.
[50] T. Griffith,et al. Intracellular regulation of TRAIL-induced apoptosis in human melanoma cells. , 1998, Journal of immunology.
[51] John C. Lee,et al. Osteoprotegerin Is a Receptor for the Cytotoxic Ligand TRAIL* , 1998, The Journal of Biological Chemistry.
[52] A. Fornace,et al. p53-dependent and -independent regulation of the death receptor KILLER/DR5 gene expression in response to genotoxic stress and tumor necrosis factor alpha. , 1998, Cancer research.
[53] V. Dixit,et al. TRUNDD, a new member of the TRAIL receptor family that antagonizes TRAIL signalling , 1998, FEBS letters.
[54] J. Bell,et al. Lymphocyte inhibitor of TRAIL (TNF-related apoptosis-inducing ligand): a new receptor protecting lymphocytes from the death ligand TRAIL. , 1998, Journal of immunology.
[55] C. Smith,et al. The novel receptor TRAIL-R4 induces NF-kappaB and protects against TRAIL-mediated apoptosis, yet retains an incomplete death domain. , 1997, Immunity.
[56] M. Peter,et al. FLICE Is Predominantly Expressed as Two Functionally Active Isoforms, Caspase-8/a and Caspase-8/b* , 1997, The Journal of Biological Chemistry.
[57] S. Srinivasula,et al. Identification and Molecular Cloning of Two Novel Receptors for the Cytotoxic Ligand TRAIL* , 1997, The Journal of Biological Chemistry.
[58] R. Dubose,et al. Cloning and Characterization of TRAIL-R3, a Novel Member of the Emerging TRAIL Receptor Family , 1997, The Journal of experimental medicine.
[59] M. Kastan. On the TRAIL from p53 to apoptosis? , 1997, Nature Genetics.
[60] J. Bell,et al. TRICK2, a new alternatively spliced receptor that transduces the cytotoxic signal from TRAIL , 1997, Current Biology.
[61] Henning Walczak,et al. TRAIL‐R2: a novel apoptosis‐mediating receptor for TRAIL , 1997, The EMBO journal.
[62] W I Wood,et al. Control of TRAIL-induced apoptosis by a family of signaling and decoy receptors. , 1997, Science.
[63] Margot Thome,et al. Inhibition of death receptor signals by cellular FLIP , 1997, Nature.
[64] Arul M. Chinnaiyan,et al. The Receptor for the Cytotoxic Ligand TRAIL , 1997, Science.
[65] J. Tschopp,et al. Viral FLICE-inhibitory proteins (FLIPs) prevent apoptosis induced by death receptors , 1997, Nature.
[66] C A Smith,et al. Identification and characterization of a new member of the TNF family that induces apoptosis. , 1995, Immunity.
[67] I Nicoletti,et al. A rapid and simple method for measuring thymocyte apoptosis by propidium iodide staining and flow cytometry. , 1991, Journal of immunological methods.
[68] Michael Weller,et al. Smac agonists sensitize for Apo2L/TRAIL- or anticancer drug-induced apoptosis and induce regression of malignant glioma in vivo , 2002, Nature Medicine.
[69] H. Wajant,et al. Selective inhibition of FLICE-like inhibitory protein expression with small interfering RNA oligonucleotides is sufficient to sensitize tumor cells for TRAIL-induced apoptosis. , 2002, Molecular medicine.
[70] Yahong Lin,et al. TRAIL-induced apoptosis requires Bax-dependent mitochondrial release of Smac/DIABLO. , 2002, Genes & development.
[71] 山中 猛成. Chemotherapeutic Agents Augment TRAIL-Induced Apoptosis in Human Hepatocellular Carcinoma Cell Lines , 2001 .
[72] M. Peter,et al. The death receptors. , 1999, Results and problems in cell differentiation.
[73] I. Krantz,et al. KILLER/DR5 is a DNA damage–inducible p53–regulated death receptor gene , 1997, Nature Genetics.
[74] J. Tschopp,et al. Characterization of two receptors for TRAIL. , 1997, FEBS letters.