Nanotechnology: A Tool for Improved Performance on Electrochemical Screen-Printed (Bio)Sensors

Screen-printing technology is a low-cost process, widely used in electronics production, especially in the fabrication of disposable electrodes for (bio)sensor applications. The pastes used for deposition of the successive layers are based on a polymeric binder with metallic dispersions or graphite, and can also contain functional materials such as cofactors, stabilizers and mediators. More recently metal nanoparticles, nanowires and carbon nanotubes have also been included either in these pastes or as a later stage on the working electrode. This review will summarize the use of nanomaterials to improve the electrochemical sensing capability of screen-printed sensors. It will cover mainly disposable sensors and biosensors for biomedical interest and toxicity monitoring, compiling recent examples where several types of metallic and carbon-based nanostructures are responsible for enhancing the performance of these devices.

[1]  Joseph Wang Nanomaterial-based electrochemical biosensors. , 2005, The Analyst.

[2]  Yuehe Lin,et al.  Solubilization of carbon nanotubes by Nafion toward the preparation of amperometric biosensors. , 2003, Journal of the American Chemical Society.

[3]  J Emnéus,et al.  Multienzyme electrochemical array sensor for determination of phenols and pesticides. , 2005, Talanta.

[4]  J. Hart,et al.  Amperometric, screen-printed, glucose biosensor for analysis of human plasma samples using a biocomposite water-based carbon ink incorporating glucose oxidase. , 2005, Analytical biochemistry.

[5]  W. Shih,et al.  Development of disposable lipid biosensor for the determination of total cholesterol. , 2009, Biosensors & bioelectronics.

[6]  R. Pemberton,et al.  Fabrication of microband glucose biosensors using a screen-printing water-based carbon ink and their application in serum analysis. , 2009, Biosensors & bioelectronics.

[7]  Lúcio Angnes,et al.  Eletrodos fabricados por "silk-screen" , 1998 .

[8]  Wen-Jun Guan,et al.  Glucose biosensor based on multi-wall carbon nanotubes and screen printed carbon electrodes. , 2005, Biosensors & bioelectronics.

[9]  Lauro T. Kubota,et al.  Determination of nitrite in food samples by anodic voltammetry using a modified electrode , 2009 .

[10]  Jean-Louis Marty,et al.  Twenty years research in cholinesterase biosensors: from basic research to practical applications. , 2006, Biomolecular engineering.

[11]  I. Tothill,et al.  Development of urease and glutamic dehydrogenase amperometric assay for heavy metals screening in polluted samples. , 2004, Biosensors & bioelectronics.

[12]  O. Renedo,et al.  A novel method for the anodic stripping voltammetry determination of Sb(III) using silver nanoparticle-modified screen-printed electrodes , 2007 .

[13]  Shu-Hua Chien,et al.  Copper-palladium alloy nanoparticle plated electrodes for the electrocatalytic determination of hydrazine , 2005 .

[14]  A. Merkoçi Electrochemical biosensing with nanoparticles , 2007, The FEBS journal.

[15]  Daren J. Caruana,et al.  Enzyme-amplified amperometric detection of hybridization and of a single base pair mutation in an 18-base oligonucleotide on a 7-μm-diameter microelectrode , 1999 .

[16]  C. Liu,et al.  An iridium nanoparticles dispersed carbon based thick film electrochemical biosensor and its application for a single use, disposable glucose biosensor , 2007 .

[17]  Itamar Willner,et al.  Integrated nanoparticle-biomolecule systems for biosensing and bioelectronics. , 2007, Biosensors & bioelectronics.

[18]  Delia B. Rodriguez-Amaya,et al.  Simultaneous determination of total lipid, cholesterol and fatty acids in meat and backfat of suckling and adult pigs , 2002 .

[19]  M. Pumera,et al.  Electrochemical genosensors for biomedical applications based on gold nanoparticles. , 2007, Biosensors & bioelectronics.

[20]  Camelia Bala,et al.  Biosensors based on screen-printing technology, and their applications in environmental and food analysis , 2007, Analytical and bioanalytical chemistry.

[21]  P R Fielden,et al.  A microband lactate biosensor fabricated using a water-based screen-printed carbon ink. , 2009, Talanta.

[22]  Danila Moscone,et al.  Detection of carbamic and organophosphorous pesticides in water samples using a cholinesterase biosensor based on Prussian Blue-modified screen-printed electrode. , 2006, Analytica chimica acta.

[23]  Zhiqiang Gao,et al.  A disposable glucose biosensor based on diffusional mediator dispersed in nanoparticulate membrane on screen-printed carbon electrode , 2005 .

[24]  Jianfu Zhao,et al.  A novel nitrite biosensor based on conductometric electrode modified with cytochrome c nitrite reductase composite membrane. , 2009, Biosensors & bioelectronics.

[25]  Jing‐Juan Xu,et al.  Multilayer membranes via layer-by-layer deposition of organic polymer protected Prussian blue nanoparticles and glucose oxidase for glucose biosensing. , 2005, Langmuir : the ACS journal of surfaces and colloids.

[26]  김병홍 Biosensor의 원리와 응용 , 1990 .

[27]  M. A. Alonso-Lomillo,et al.  CYP450 2B4 covalently attached to carbon and gold screen printed electrodes by diazonium salt and thiols monolayers. , 2009, Analytica chimica acta.

[28]  Olga Domínguez-Renedo,et al.  Electrochemical determination of chromium(VI) using metallic nanoparticle-modified carbon screen-printed electrodes. , 2008, Talanta.

[29]  Liang Ding,et al.  Development of an amperometric biosensor based on glucose oxidase immobilized through silica sol–gel film onto Prussian Blue modified electrode , 2004 .

[30]  Joseph Wang,et al.  Glucose microsensors based on carbon paste enzyme electrodes modified with cupric hexacyanoferrate , 1999 .

[31]  Umasankar Yogeswaran,et al.  A Review on the Electrochemical Sensors and Biosensors Composed of Nanowires as Sensing Material , 2008, Sensors.

[32]  Ronen Polsky,et al.  Magnetically-induced solid-state electrochemical detection of DNA hybridization. , 2002, Journal of the American Chemical Society.

[33]  S J Kim,et al.  A disposable amperometric sensor screen printed on a nitrocellulose strip: a glucose biosensor employing lead oxide as an interference-removing agent. , 2000, Analytical chemistry.

[34]  A. Salimi,et al.  Electrochemical properties and electrocatalytic activity of FAD immobilized onto cobalt oxide nanoparticles : Application to nitrite detection , 2008 .

[35]  Kagan Kerman,et al.  Electrochemical genosensor for the detection of interaction between methylene blue and DNA , 2002 .

[36]  Saverio Mannino,et al.  Adaptive nanowire-nanotube bioelectronic system for on-demand bioelectrocatalytic transformations. , 2007, Chemical communications.

[37]  Ladislav Novotný,et al.  Label-free determination of picogram quantities of DNA by stripping voltammetry with solid copper amalgam or mercury electrodes in the presence of copper. , 2002, Analytical chemistry.

[38]  Arben Merkoçi,et al.  Configurations used in the design of screen-printed enzymatic biosensors. A review , 2000 .

[39]  John P. Hart,et al.  Some Recent Designs and Developments of Screen‐Printed Carbon Electrochemical Sensors/Biosensors for Biomedical, Environmental, and Industrial Analyses , 2004 .

[40]  Ulla Wollenberger,et al.  Cytochrome P450 biosensors-a review. , 2005, Biosensors & bioelectronics.

[41]  Ronen Polsky,et al.  Electrochemical detection of DNA hybridization based on DNA-templated assembly of silver cluster , 2003 .

[42]  Joseph Wang,et al.  "Nanofingers" based on binary gold-polypyrrole nanowires. , 2008, Small.

[43]  John P. Hart,et al.  Screen-printed electrochemical sensors for monitoring metal pollutants , 2003 .

[44]  F Ricci,et al.  Sensor and biosensor preparation, optimisation and applications of Prussian Blue modified electrodes. , 2005, Biosensors & bioelectronics.

[45]  Daren J. Caruana,et al.  Enzyme-amplified amperometric detection of hybridization and of a single base pair mutation in an 18-base oligonucleotide on a 7-mu m-diameter microelectrode (vol 121, pg 769, 1999) , 1999 .

[46]  Thomas J. Morrow,et al.  Nanowire sensors for multiplexed detection of biomolecules. , 2008, Current opinion in chemical biology.

[47]  J. Hart,et al.  Development of a disposable ethanol biosensor based on a chemically modified screen-printed electrode coated with alcohol oxidase for the analysis of beer. , 2000, Biosensors & bioelectronics.

[48]  William R. Heineman,et al.  Nanotube electrodes and biosensors , 2007 .

[49]  A. Erdem,et al.  Nanomaterial-based electrochemical DNA sensing strategies. , 2007, Talanta.

[50]  Wen‐Chang Chen,et al.  A disposable glucose biosensor based on drop-coating of screen-printed carbon electrodes with magnetic nanoparticles , 2006 .

[51]  G. Sergeev,et al.  Nanoparticles in Science and Technology , 2006 .

[52]  Thomas J. Morrow,et al.  Programmed Assembly of DNA-Coated Nanowire Devices , 2009, Science.

[53]  Federica Valentini,et al.  Magnetic tuning of the electrochemical reactivity through controlled surface orientation of catalytic nanowires. , 2006, Journal of the American Chemical Society.

[54]  Sandro Carrara,et al.  Cholesterol amperometric biosensor based on cytochrome P450scc. , 2004, Biosensors & bioelectronics.

[55]  Jean-Louis Marty,et al.  A Screen‐Printed, Amperometric, Biosensor Array for the Detection of Organophosphate Pesticides Based on Inhibition of Wild Type, and Mutant Acetylcholinesterases, from Drosophila melanogaster , 2004 .

[56]  Yang-Kyu Choi,et al.  Chemical sensors based on nanostructured materials , 2007 .

[57]  Joseph Wang Carbon‐Nanotube Based Electrochemical Biosensors: A Review , 2005 .

[58]  Wen-Chang Chen,et al.  A disposable amperometric ethanol biosensor based on screen-printed carbon electrodes mediated with ferricyanide-magnetic nanoparticle mixture , 2006 .

[59]  Julio Raba,et al.  Screen-printed enzymatic biosensor modified with carbon nanotube for the methimazole determination in pharmaceuticals formulations , 2008 .

[60]  J. Moura,et al.  Biosensing nitrite using the system nitrite redutase/Nafion/methyl viologen--a voltammetric study. , 2007, Biosensors & bioelectronics.

[61]  Marco Mascini,et al.  Planar electrochemical sensors for biomedical applications. , 2006, Medical engineering & physics.

[62]  Ilaria Palchetti,et al.  Disposable electrodes modified with multi-wall carbon nanotubes for biosensor applications , 2008 .

[63]  G. Marrazza,et al.  Development of disposable low density screen-printed electrode arrays for simultaneous electrochemical measurements of the hybridisation reaction , 2006 .

[64]  Sandro Carrara,et al.  Screen-printed electrodes based on carbon nanotubes and cytochrome P450scc for highly sensitive cholesterol biosensors. , 2008, Biosensors & bioelectronics.

[65]  A. Archakov,et al.  Au-nanoparticles as an electrochemical sensing platform for aptamer-thrombin interaction. , 2008, Biosensors & bioelectronics.

[66]  Martin Pumera,et al.  Electrochemical nanobiosensors , 2007 .

[67]  I. Tothill,et al.  Urease–glutamic dehydrogenase biosensor for screening heavy metals in water and soil samples , 2004, Analytical and bioanalytical chemistry.

[68]  Tautgirdas Ruzgas,et al.  Sensor and biosensor based on Prussian Blue modified gold and platinum screen printed electrodes. , 2003, Biosensors & bioelectronics.

[69]  Joseph Wang,et al.  Adaptive orientation of multifunctional nanowires for magnetic control of bioelectrocatalytic processes. , 2007, Angewandte Chemie.

[70]  Giuseppe Palleschi,et al.  Screen-printed enzyme electrodes for the detection of marker analytes during winemaking , 2004 .

[71]  Sachin R. Jadhav,et al.  Functional characterization of PorB class II porin from Neisseria meningitidis using a tethered bilayer lipid membrane. , 2008, Biosensors & bioelectronics.

[72]  M. Martínez,et al.  Anodic stripping voltammetry of antimony using gold nanoparticle-modified carbon screen-printed electrodes. , 2007 .

[73]  A. Turner,et al.  Home blood glucose biosensors: a commercial perspective. , 2005, Biosensors & bioelectronics.

[74]  Dan Du,et al.  A disposable sensor based on immobilization of acetylcholinesterase to multiwall carbon nanotube modified screen-printed electrode for determination of carbaryl , 2008 .

[75]  S. Kuwabata,et al.  Electrochemical oxidation of cholesterol catalyzed by cholesterol oxidase with use of an artificial electron mediator. , 1997, Analytical chemistry.

[76]  J. Hart,et al.  A novel, disposable, screen-printed amperometric biosensor for glucose in serum fabricated using a water-based carbon ink. , 2005, Biosensors & bioelectronics.

[77]  Jian Shen,et al.  A novel nitrite biosensor based on the direct electron transfer of hemoglobin immobilized on CdS hollow nanospheres. , 2008, Biosensors & bioelectronics.

[78]  Alfredo de la Escosura-Muñiz,et al.  Electrochemical analysis with nanoparticle-based biosystems , 2008 .

[79]  D. Andreescu,et al.  Biosensors designed for environmental and food quality control based on screen-printed graphite electrodes with different configurations , 2002, Analytical and bioanalytical chemistry.

[80]  Joseph Wang,et al.  Disposable Carbon Nanotube Modified Screen‐Printed Biosensor for Amperometric Detection of Organophosphorus Pesticides and Nerve Agents , 2004 .

[81]  Olga Domínguez-Renedo,et al.  Electrochemical determination of levetiracetam by screen-printed based biosensors. , 2009, Bioelectrochemistry.

[82]  Agustín Costa-García,et al.  Manufacture and evaluation of carbon nanotube modified screen-printed electrodes as electrochemical tools. , 2007, Talanta.

[83]  Sandro Carrara,et al.  Direct electron transfer between cytochrome P450scc and gold nanoparticles on screen-printed rhodium-graphite electrodes. , 2005, Biosensors & bioelectronics.

[84]  Serge Cosnier,et al.  A new approach for nitrite determination based on a HRP/catalase biosensor , 2008 .

[85]  N. Murr,et al.  Amperometric determination of cholesterol in serum with use of a renewable surface peroxidase electrode , 1995 .

[86]  Charlotte Carlsson,et al.  Amperometric screen-printed biosensor arrays with co-immobilised oxidoreductases and cholinesterases , 2005 .

[87]  Lun Wang,et al.  Electrochemical determination of nitrite and iodate by use of gold nanoparticles/poly(3-methylthiophene) composites coated glassy carbon electrode , 2008 .

[88]  G. Li,et al.  Study of carbon nanotube modified biosensor for monitoring total cholesterol in blood. , 2005, Biosensors & bioelectronics.

[89]  Shaohua Zuo,et al.  Development of a Novel Silver Nanoparticles-Enhanced Screen-Printed Amperometric Glucose Biosensor , 2008 .

[90]  P. A. Fiorito,et al.  Synthesis, characterization and immobilization of Prussian blue nanoparticles. A potential tool for biosensing devices. , 2005, Chemical communications.

[91]  Jaco Vangronsveld,et al.  Biosensors for detection of mercury in contaminated soils. , 2004, Environmental pollution.

[92]  John P. Hart,et al.  Screen-printed electrochemical (bio)sensors in biomedical, environmental and industrial applications , 2007 .

[93]  L. Authier,et al.  Gold nanoparticle-based quantitative electrochemical detection of amplified human cytomegalovirus DNA using disposable microband electrodes. , 2001, Analytical chemistry.

[94]  M. A. Alonso-Lomillo,et al.  Recent developments in the field of screen-printed electrodes and their related applications. , 2007, Talanta.

[95]  Saverio Mannino,et al.  On-demand protection of electrochemical sensors based on adaptive nanowires. , 2007, Journal of the American Chemical Society.

[96]  Gábor Harsányi,et al.  Amperometric uric acid biosensors fabricated of various types of uricase enzymes , 2003 .

[97]  Krzysztof Miecznikowski,et al.  Application of Prussian Blue Based Composite Film with Functionalized Organic Polymer to Construction of Enzymatic Glucose Biosensor , 2003 .

[98]  Eric Bakker,et al.  Electrochemical sensors. , 2002, Analytical chemistry.

[99]  Yuehe Lin,et al.  Carbon nanotube-based electrochemical sensor for assay of salivary cholinesterase enzyme activity: an exposure biomarker of organophosphate pesticides and nerve agents. , 2008, Environmental science & technology.

[100]  G. Rivas,et al.  Carbon nanotubes paste electrode , 2003 .

[101]  R. Compton,et al.  The use of nanoparticles in electroanalysis: a review , 2006, Analytical and bioanalytical chemistry.

[102]  Bao-Shyung Hwang,et al.  A simplified method for the quantification of total cholesterol in lipids using gas chromatography , 2003 .

[103]  Emanuel Carrilho,et al.  Adaptive nanowires for switchable microchip devices. , 2007, Analytical chemistry.

[104]  J Wang,et al.  Disposable screen-printed electrodes for monitoring hydrazines. , 1995, Talanta.

[105]  Jean-Louis Marty,et al.  Immobilization of acetylcholinesterase on screen-printed electrodes: comparative study between three immobilization methods and applications to the detection of organophosphorus insecticides , 2002 .

[106]  R. R. Holman,et al.  PEN-SIZED DIGITAL 30-SECOND BLOOD GLUCOSE METER , 1987, The Lancet.

[107]  S. Adeloju,et al.  Electroimmobilization of nitrate reductase and nicotinamide adenine dinucleotide into polypyrrole films for potentiometric detection of nitrate , 2008 .

[108]  John P. Hart,et al.  Fabrication and characterization of a screen-printed, disposable, amperometric cholesterol biosensor , 1994 .

[109]  Kathryn L. Turner,et al.  “Electroactive Beads” for Ultrasensitive DNA Detection , 2003 .

[110]  M. Martínez,et al.  Determination of lamotrigine by adsorptive stripping voltammetry using silver nanoparticle-modified carbon screen-printed electrodes. , 2007 .

[111]  Michael Grätzel,et al.  A glucose biosensor based on enzyme entrapment within polypyrrole films electrodeposited on mesoporous titanium dioxide , 1999 .

[112]  Jyh-Myng Zen,et al.  Screen Printed Carbon Electrode Modified with Poly(L‐Lactide) Stabilized Gold Nanoparticles for Sensitive As(III) Detection , 2006 .

[113]  Ming-Chih Ho,et al.  A planar interdigitated ring electrode array via dielectrophoresis for uniform patterning of cells. , 2008, Biosensors & bioelectronics.

[114]  Enric Cabruja,et al.  Carbon nanotube/polysulfone composite screen-printed electrochemical enzyme biosensors. , 2007, In Analysis.

[115]  P. Alivisatos The use of nanocrystals in biological detection , 2004, Nature Biotechnology.

[116]  G. Rivas,et al.  Carbon nanotubes for electrochemical biosensing. , 2007, Talanta.

[117]  Javier Muñoz,et al.  Glucose biosensor strip in a three electrode configuration based on composite and biocomposite materials applied by planar thick film technology , 1998 .

[118]  Min Zhao,et al.  Carbon nanotube-enhanced DNA biosensor for DNA hybridization detection using rutin-Mn as electrochemical indicator , 2008 .

[119]  Zeev Rosenzweig,et al.  Glucose oxidase–magnetite nanoparticle bioconjugate for glucose sensing , 2004, Analytical and bioanalytical chemistry.

[120]  Bing Li,et al.  Disposable Nitrite Sensor Based on Hemoglobin-Colloidal Gold Nanoparticle Modified Screen-Printed Electrode , 2003 .

[121]  D Schomburg,et al.  Crystal structure of glucose oxidase from Aspergillus niger refined at 2.3 A resolution. , 1993, Journal of molecular biology.

[122]  Bansi D Malhotra,et al.  Recent advances in cholesterol biosensor. , 2008, Biosensors & bioelectronics.

[123]  Stanisław Głąb,et al.  Screen-printed disposable urease-based biosensors for inhibitive detection of heavy metal ions , 2005 .

[124]  Serge Cosnier,et al.  Highly sensitive nitrite biosensor based on the electrical wiring of nitrite reductase by [ZnCr-AQS] LDH , 2007 .

[125]  Xi Chen,et al.  CdTe nanocrystal-based electrochemical biosensor for the recognition of neutravidin by anodic stripping voltammetry at electrodeposited bismuth film. , 2008, Biosensors & bioelectronics.

[126]  Olga Domínguez Renedo,et al.  Anodic stripping voltammetry of antimony using gold nanoparticle-modified carbon screen-printed electrodes. , 2007, Analytica chimica acta.

[127]  N. Chaniotakis,et al.  Carbon nanostructures as transducers in biosensors , 2007 .

[128]  Hafedh Ben Ouada,et al.  Electrochemical sensor for nitrite determination based on thin films of sulfamic acid doped polyaniline deposited on Si/SiO2 structures in electrolyte/insulator/semiconductor (E.I.S.) configuration , 2008 .

[129]  S. Cosnier,et al.  Electrochemical nitrate biosensor based on poly(pyrrole-viologen) film-nitrate reductase-clay composite. , 2008, Bioelectrochemistry.

[130]  Jyh-Myng Zen,et al.  Trace analysis of hydrogen sulfide by monitoring As(III) at a poly(l-lactide) stabilized gold nanoparticles modified electrode , 2006 .