Origins and Mechanisms of miRNAs and siRNAs
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[1] Petra Schwille,et al. Importin 8 Is a Gene Silencing Factor that Targets Argonaute Proteins to Distinct mRNAs , 2009, Cell.
[2] H. Grosshans,et al. Repression of C. elegans microRNA targets at the initiation level of translation requires GW182 proteins , 2009, The EMBO journal.
[3] D. Moazed. Small RNAs in transcriptional gene silencing and genome defence , 2009, Nature.
[4] T. Tuschl,et al. Structure of an argonaute silencing complex with a seed-containing guide DNA and target RNA duplex , 2008, Nature.
[5] M. Zavolan,et al. Molecular characterization of human Argonaute-containing ribonucleoprotein complexes and their bound target mRNAs. , 2008, RNA.
[6] N. Rajewsky,et al. A human snoRNA with microRNA-like functions. , 2008, Molecular cell.
[7] C. Pikaard,et al. Noncoding Transcription by RNA Polymerase Pol IVb/Pol V Mediates Transcriptional Silencing of Overlapping and Adjacent Genes , 2008, Cell.
[8] T. Tuschl,et al. Structure of the guide-strand-containing argonaute silencing complex , 2008, Nature.
[9] C. Joo,et al. Lin28 mediates the terminal uridylation of let-7 precursor MicroRNA. , 2008, Molecular cell.
[10] G. Meister,et al. Fluorescence correlation spectroscopy and fluorescence cross-correlation spectroscopy reveal the cytoplasmic origination of loaded nuclear RISC in vivo in human cells , 2008, Nucleic acids research.
[11] E. Sontheimer,et al. An inside job for siRNAs. , 2008, Molecular cell.
[12] J. M. Thomson,et al. Lin-28 interaction with the Let-7 precursor loop mediates regulated microRNA processing. , 2008, RNA.
[13] L. Smirnova,et al. A feedback loop comprising lin-28 and let-7 controls pre-let-7 maturation during neural stem-cell commitment , 2008, Nature Cell Biology.
[14] Jack F Kirsch,et al. Autoinhibition of human dicer by its internal helicase domain. , 2008, Journal of molecular biology.
[15] A. F. Bochner,et al. An Argonaute Transports siRNAs from the Cytoplasm to the Nucleus , 2008, Science.
[16] L. Sieburth,et al. Widespread Translational Inhibition by Plant miRNAs and siRNAs , 2008, Science.
[17] U. A. Ørom,et al. MicroRNA-10a binds the 5'UTR of ribosomal protein mRNAs and enhances their translation. , 2008, Molecular cell.
[18] C. Novina,et al. MicroRNA-repressed mRNAs contain 40S but not 60S components , 2008, Proceedings of the National Academy of Sciences.
[19] G. Daley,et al. Selective Blockade of MicroRNA Processing by Lin28 , 2008, Science.
[20] Hong Duan,et al. The regulatory activity of microRNA* species has substantial influence on microRNA and 3′ UTR evolution , 2008, Nature Structural &Molecular Biology.
[21] E. Izaurralde,et al. GW182 interaction with Argonaute is essential for miRNA-mediated translational repression and mRNA decay , 2008, Nature Structural &Molecular Biology.
[22] Jian Lu,et al. The birth and death of microRNA genes in Drosophila , 2008, Nature Genetics.
[23] Jennifer A. Doudna,et al. In vitro reconstitution of the human RISC-loading complex , 2008, Proceedings of the National Academy of Sciences.
[24] J. Steitz,et al. Switching from Repression to Activation: MicroRNAs Can Up-Regulate Translation , 2007, Science.
[25] G. Meister,et al. Proteomic and functional analysis of Argonaute‐containing mRNA–protein complexes in human cells , 2007, EMBO reports.
[26] M. Hentze,et al. A conserved motif in Argonaute-interacting proteins mediates functional interactions through the Argonaute PIWI domain , 2007, Nature Structural &Molecular Biology.
[27] I. MacRae,et al. Structural determinants of RNA recognition and cleavage by Dicer , 2007, Nature Structural &Molecular Biology.
[28] Takayuki Murata,et al. MicroRNA Inhibition of Translation Initiation in Vitro by Targeting the Cap-Binding Complex eIF4F , 2007, Science.
[29] Shigeyuki Yokoyama,et al. Let-7 microRNA-mediated mRNA deadenylation and translational repression in a mammalian cell-free system. , 2007, Genes & development.
[30] Phillip D. Zamore,et al. Sorting of Drosophila Small Silencing RNAs , 2007, Cell.
[31] Phillip D. Zamore,et al. Drosophila microRNAs Are Sorted into Functionally Distinct Argonaute Complexes after Production by Dicer-1 , 2007, Cell.
[32] E. Lai,et al. The Mirtron Pathway Generates microRNA-Class Regulatory RNAs in Drosophila , 2007, Cell.
[33] D. Bartel,et al. Intronic microRNA precursors that bypass Drosha processing , 2007, Nature.
[34] M. Kiriakidou,et al. An mRNA m7G Cap Binding-like Motif within Human Ago2 Represses Translation , 2007, Cell.
[35] A. Pasquinelli,et al. MicroRNA silencing through RISC recruitment of eIF6 , 2007, Nature.
[36] Matthias W. Hentze,et al. Drosophila miR2 induces pseudo-polysomes and inhibits translation initiation , 2007, Nature.
[37] J. Steitz,et al. Target mRNAs are repressed as efficiently by microRNA-binding sites in the 5′ UTR as in the 3′ UTR , 2007, Proceedings of the National Academy of Sciences.
[38] S. Grewal,et al. Transcription and RNA interference in the formation of heterochromatin , 2007, Nature.
[39] I. Henderson,et al. Epigenetic inheritance in plants , 2007, Nature.
[40] Isabelle Behm-Ansmant,et al. P-Body Formation Is a Consequence, Not the Cause, of RNA-Mediated Gene Silencing , 2007, Molecular and Cellular Biology.
[41] John G Doench,et al. Comparison of siRNA-induced off-target RNA and protein effects. , 2007, RNA.
[42] Titia Sijen,et al. Secondary siRNAs Result from Unprimed RNA Synthesis and Form a Distinct Class , 2007, Science.
[43] Andrew Fire,et al. Distinct Populations of Primary and Secondary Effectors During RNAi in C. elegans , 2007, Science.
[44] E. Wentzel,et al. A Hexanucleotide Element Directs MicroRNA Nuclear Import , 2007, Science.
[45] R. Carthew,et al. Conversion of pre-RISC to holo-RISC by Ago2 during assembly of RNAi complexes. , 2006, RNA.
[46] J. Richter,et al. Human let-7a miRNA blocks protein production on actively translating polyribosomes , 2006, Nature Structural &Molecular Biology.
[47] Anthony K. L. Leung,et al. Quantitative analysis of Argonaute protein reveals microRNA-dependent localization to stress granules , 2006, Proceedings of the National Academy of Sciences.
[48] Yang Yu,et al. Evidence that microRNAs are associated with translating messenger RNAs in human cells , 2006, Nature Structural &Molecular Biology.
[49] Pedro J. Batista,et al. Analysis of the C. elegans Argonaute Family Reveals that Distinct Argonautes Act Sequentially during RNAi , 2006, Cell.
[50] P. Bork,et al. mRNA degradation by miRNAs and GW182 requires both CCR4:NOT deadenylase and DCP1:DCP2 decapping complexes. , 2006, Genes & development.
[51] T. Rana,et al. Translation Repression in Human Cells by MicroRNA-Induced Gene Silencing Requires RCK/p54 , 2006, PLoS biology.
[52] Marc Bühler,et al. Tethering RITS to a Nascent Transcript Initiates RNAi- and Heterochromatin-Dependent Gene Silencing , 2006, Cell.
[53] Byoung-Tak Zhang,et al. Molecular Basis for the Recognition of Primary microRNAs by the Drosha-DGCR8 Complex , 2006, Cell.
[54] Anton J. Enright,et al. Zebrafish MiR-430 Promotes Deadenylation and Clearance of Maternal mRNAs , 2006, Science.
[55] Ligang Wu,et al. MicroRNAs direct rapid deadenylation of mRNA. , 2006, Proceedings of the National Academy of Sciences of the United States of America.
[56] Jerry Pelletier,et al. Short RNAs repress translation after initiation in mammalian cells. , 2006, Molecular cell.
[57] Angela N. Brooks,et al. Structural Basis for Double-Stranded RNA Processing by Dicer , 2006, Science.
[58] Xin Li,et al. A microRNA Mediates EGF Receptor Signaling and Promotes Photoreceptor Differentiation in the Drosophila Eye , 2005, Cell.
[59] Z. Mourelatos,et al. A human, ATP-independent, RISC assembly machine fueled by pre-miRNA. , 2005, Genes & development.
[60] T. Tuschl,et al. Identification of Novel Argonaute-Associated Proteins , 2005, Current Biology.
[61] M. Siomi,et al. Slicer function of Drosophila Argonautes and its involvement in RISC formation. , 2005, Genes & development.
[62] David I. K. Martin,et al. MicroRNAs control translation initiation by inhibiting eukaryotic initiation factor 4E/cap and poly(A) tail function. , 2005, Proceedings of the National Academy of Sciences of the United States of America.
[63] R. Shiekhattar,et al. Human RISC Couples MicroRNA Biogenesis and Posttranscriptional Gene Silencing , 2005, Cell.
[64] Xiaodong Wang,et al. Argonaute2 Cleaves the Anti-Guide Strand of siRNA during RISC Activation , 2005, Cell.
[65] David P. Bartel,et al. Passenger-Strand Cleavage Facilitates Assembly of siRNA into Ago2-Containing RNAi Enzyme Complexes , 2005, Cell.
[66] J. Yates,et al. A role for the P-body component GW182 in microRNA function , 2005, Nature Cell Biology.
[67] E. Chan,et al. Disruption of GW bodies impairs mammalian RNA interference , 2005, Nature Cell Biology.
[68] C. Bonilla,et al. RNA Pol II subunit Rpb7 promotes centromeric transcription and RNAi-directed chromatin silencing. , 2005, Genes & development.
[69] W. Filipowicz,et al. Inhibition of Translational Initiation by Let-7 MicroRNA in Human Cells , 2005, Science.
[70] A. Pasquinelli,et al. Regulation by let-7 and lin-4 miRNAs Results in Target mRNA Degradation , 2005, Cell.
[71] Oliver H. Tam,et al. Characterization of Dicer-deficient murine embryonic stem cells. , 2005, Proceedings of the National Academy of Sciences of the United States of America.
[72] T. Tuschl,et al. Crystal structure of A. aeolicus argonaute, a site-specific DNA-guided endoribonuclease, provides insights into RISC-mediated mRNA cleavage. , 2005, Molecular cell.
[73] Qinghua Liu,et al. Dicer-1 and R3D1-L catalyze microRNA maturation in Drosophila. , 2005, Genes & development.
[74] R. Martienssen,et al. RNA Polymerase II Is Required for RNAi-Dependent Heterochromatin Assembly , 2005, Science.
[75] Gregory J. Hannon,et al. MicroRNA-dependent localization of targeted mRNAs to mammalian P-bodies , 2005, Nature Cell Biology.
[76] Kuniaki Saito,et al. Processing of Pre-microRNAs by the Dicer-1–Loquacious Complex in Drosophila Cells , 2005, PLoS biology.
[77] A. Denli,et al. Normal microRNA Maturation and Germ-Line Stem Cell Maintenance Requires Loquacious, a Double-Stranded RNA-Binding Domain Protein , 2005, PLoS biology.
[78] V. Kim. MicroRNA biogenesis: coordinated cropping and dicing , 2005, Nature Reviews Molecular Cell Biology.
[79] A. Reynolds,et al. The contributions of dsRNA structure to Dicer specificity and efficiency. , 2005, RNA.
[80] Adam M. Gustafson,et al. microRNA-Directed Phasing during Trans-Acting siRNA Biogenesis in Plants , 2005, Cell.
[81] Elisa Izaurralde,et al. Decay of mRNAs targeted by RISC requires XRN1, the Ski complex, and the exosome. , 2005, RNA.
[82] D. Baulcombe,et al. RNA Polymerase IV Directs Silencing of Endogenous DNA , 2005, Science.
[83] Ji-Joon Song,et al. Purified Argonaute2 and an siRNA form recombinant human RISC , 2005, Nature Structural &Molecular Biology.
[84] Thomas Tuschl,et al. Structural basis for 5′-end-specific recognition of guide RNA by the A. fulgidus Piwi protein , 2005, Nature.
[85] D. Barford,et al. Structural insights into mRNA recognition from a PIWI domain–siRNA guide complex , 2005, Nature.
[86] C. Pikaard,et al. Plant Nuclear RNA Polymerase IV Mediates siRNA and DNA Methylation-Dependent Heterochromatin Formation , 2005, Cell.
[87] Phillip D Zamore,et al. Perspective: machines for RNAi. , 2005, Genes & development.
[88] J. Castle,et al. Microarray analysis shows that some microRNAs downregulate large numbers of target mRNAs , 2005, Nature.
[89] Shridar Ganesan,et al. Dicer-deficient mouse embryonic stem cells are defective in differentiation and centromeric silencing. , 2005, Genes & development.
[90] T. Rana,et al. Specific and potent RNAi in the nucleus of human cells , 2005, Nature Structural &Molecular Biology.
[91] T. Sugiyama,et al. RNA-dependent RNA polymerase is an essential component of a self-enforcing loop coupling heterochromatin assembly to siRNA production. , 2005, Proceedings of the National Academy of Sciences of the United States of America.
[92] D. Barford,et al. Crystal structure of a PIWI protein suggests mechanisms for siRNA recognition and slicer activity , 2004, The EMBO journal.
[93] G. Hannon,et al. Processing of primary microRNAs by the Microprocessor complex , 2004, Nature.
[94] H. Goodman,et al. Uridine Addition After MicroRNA-Directed Cleavage , 2004, Science.
[95] Franck Vazquez,et al. Endogenous trans-acting siRNAs regulate the accumulation of Arabidopsis mRNAs. , 2004, Molecular cell.
[96] W. Filipowicz,et al. Tethering of human Ago proteins to mRNA mimics the miRNA-mediated repression of protein synthesis. , 2004, RNA.
[97] R. Martienssen,et al. The role of RNA interference in heterochromatic silencing , 2004, Nature.
[98] T. Tuschl,et al. Mechanisms of gene silencing by double-stranded RNA , 2004, Nature.
[99] C. Mello,et al. Revealing the world of RNA interference , 2004, Nature.
[100] G. Hannon,et al. Crystal Structure of Argonaute and Its Implications for RISC Slicer Activity , 2004, Science.
[101] Eric Westhof,et al. Single Processing Center Models for Human Dicer and Bacterial RNase III , 2004, Cell.
[102] D. Bartel. MicroRNAs Genomics, Biogenesis, Mechanism, and Function , 2004, Cell.
[103] V. Kim,et al. The nuclear RNase III Drosha initiates microRNA processing , 2003, Nature.
[104] E. Moss,et al. Two genetic circuits repress the Caenorhabditis elegans heterochronic gene lin-28 after translation initiation. , 2002, Developmental biology.
[105] S. Hammond,et al. An RNA-directed nuclease mediates post-transcriptional gene silencing in Drosophila cells , 2000, Nature.
[106] P. Mantica,et al. The Decay of , 2000 .
[107] T. Hobman,et al. GERp95, a membrane-associated protein that belongs to a family of proteins involved in stem cell differentiation. , 1999, Molecular biology of the cell.
[108] S. B. Atienza-Samols,et al. With Contributions by , 1978 .
[109] W. J. Hadden,et al. A Comparison of , 1971 .