Segmentation of X-ray Images by 3D-2D Registration Based on Multibody Physics

X-ray imaging is commonly used in clinical routine. In radiotherapy, spatial information is extracted from X-ray images to correctly position patients before treatment. Similarly, orthopedic surgeons assess the positioning and migration of implants after Total Hip Replacement (THR) with X-ray images. However, the projective nature of X-ray imaging hinders the reliable extraction of rigid structures in X-ray images, such as bones or metallic components. We developed an approach based on multibody physics that simultaneously registers multiple 3D shapes with one or more 2D X-ray images. Considered as physical bodies, shapes are driven by image forces, which exploit image gradient, and constraints, which enforce spatial dependencies between shapes. Our method was tested on post-operative radiographs of THR and thoroughly validated with gold standard datasets. The final target registration error was in average \(0.3\pm 0.16\) mm and the capture range improved more than 40 % with respect to reference registration methods.

[1]  L. Joskowicz,et al.  Gradient-based 2-D/3-D rigid registration of fluoroscopic X-ray to CT , 2003, IEEE Transactions on Medical Imaging.

[2]  Leo Joskowicz,et al.  Registration of a CT-like atlas to fluoroscopic X-ray images using intensity correspondences , 2008, International Journal of Computer Assisted Radiology and Surgery.

[3]  Frédéric Truchetet,et al.  Mesh Comparison Using Attribute Deviation Metric , 2004, Int. J. Image Graph..

[4]  Bostjan Likar,et al.  3-D/2-D registration by integrating 2-D information in 3-D , 2006, IEEE Transactions on Medical Imaging.

[5]  D. Murray The definition and measurement of acetabular orientation. , 1993, The Journal of bone and joint surgery. British volume.

[6]  Mohamed R Mahfouz,et al.  Effect of segmentation errors on 3D-to-2D registration of implant models in X-ray images. , 2005, Journal of biomechanics.

[7]  Josien P. W. Pluim,et al.  Evaluation of optimization methods for intensity-based 2D-3D registration in x-ray guided interventions , 2011, Medical Imaging.

[8]  Graeme P. Penney,et al.  Standardized evaluation methodology for 2-D-3-D registration , 2005, IEEE Transactions on Medical Imaging.

[9]  D. Paulus,et al.  2D/3D image registration on the GPU , 2008, Pattern Recognition and Image Analysis.

[10]  Sébastien Ourselin,et al.  Block Matching: A General Framework to Improve Robustness of Rigid Registration of Medical Images , 2000, MICCAI.

[11]  Max Mignotte,et al.  3D/2D registration and segmentation of scoliotic vertebrae using statistical models. , 2003, Computerized medical imaging and graphics : the official journal of the Computerized Medical Imaging Society.

[12]  Bostjan Likar,et al.  A review of 3D/2D registration methods for image-guided interventions , 2012, Medical Image Anal..

[13]  Nassir Navab,et al.  2D/3D registration based on volume gradients , 2005, SPIE Medical Imaging.

[14]  Tomaz Slivnik,et al.  3-D/2-D registration of CT and MR to X-ray images , 2003, IEEE Transactions on Medical Imaging.

[15]  Jürgen Weese,et al.  A comparison of similarity measures for use in 2-D-3-D medical image registration , 1998, IEEE Transactions on Medical Imaging.

[16]  G. Kuduvalli,et al.  A fast, accurate, and automatic 2D-3D image registration for image-guided cranial radiosurgery. , 2008, Medical physics.

[17]  Guoyan Zheng,et al.  Validation of a statistical shape model-based 2D/3D reconstruction method for determination of cup orientation after THA , 2012, International Journal of Computer Assisted Radiology and Surgery.

[18]  Nadia Magnenat-Thalmann,et al.  MRI Bone Segmentation Using Deformable Models and Shape Priors , 2008, MICCAI.

[19]  Bostjan Likar,et al.  Robust Gradient-Based 3-D/2-D Registration of CT and MR to X-Ray Images , 2008, IEEE Transactions on Medical Imaging.

[20]  Ryo Kurazume,et al.  3D reconstruction of a femoral shape using a parametric model and two 2D fluoroscopic images , 2007, Proceedings 2007 IEEE International Conference on Robotics and Automation.

[21]  Hideki Yoshikawa,et al.  In vivo kinematic analysis of squatting after total hip arthroplasty. , 2011, Clinical biomechanics.