Cloning and Expression of a Rat Brain Interleukin-1 b-Converting Enzyme ( ICE )-Related Protease ( IRP ) and Its Possible Role in Apoptosis of Cultured Cerebellar Granule Neurons

1Lilly Research Laboratories, Eli Lilly and Company, Indianapolis, Indiana 46285, 2Poly (ADP-Ribose) Polymerase Metabolism Group, Laboratory of Molecular Endocrinology, Centre Hospitalier de l’Université Laval Research Center and Laval University, Sainte-Foy, Québec, Canada, G1V 4G2, and Departments of 3Pharmacology and Toxicology and 4Psychiatry, School of Medicine, Indiana University, Indianapolis, Indiana 46202

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