The broad-spectrum antiemetic effects ETI-385 result from stimulation of 5-HT1A and 5-HT1D receptors

[1]  J. Rudd,et al.  Looking beyond 5-HT(3) receptors: a review of the wider role of serotonin in the pharmacology of nausea and vomiting. , 2014, European journal of pharmacology.

[2]  Joanna L. Sharman,et al.  IUPHAR-DB: updated database content and new features , 2012, Nucleic Acids Res..

[3]  P. Kranke,et al.  Intravenous buspirone for the prevention of postoperative nausea and vomiting , 2012, European Journal of Clinical Pharmacology.

[4]  J. Lucot,et al.  Guamanian Suncus murinus responsiveness to emetic stimuli and the antiemetic effects of 8-OH-DPAT , 2011, Pharmacology Biochemistry and Behavior.

[5]  R. Naylor,et al.  The effect of the 5-HT1A receptor agonist, 8-OH-DPAT, on motion-induced emesis in Suncus murinus , 2006, Pharmacology Biochemistry and Behavior.

[6]  Michal Brylinski,et al.  Stereoselectivity of 8-OH-DPAT toward the serotonin 5-HT1A receptor: biochemical and molecular modeling study. , 2006, Biochemical pharmacology.

[7]  H. Lutsep Repinotan, A 5-HT1A agonist, in the treatment of acute ischemic stroke. , 2005, Current Drug Targets - CNS & Neurological Disorders.

[8]  Y. Gupta,et al.  Involvement of 5-HT1A and 5-HT2 receptor in cisplatin induced emesis in dogs. , 2002, Indian journal of physiology and pharmacology.

[9]  J. Greuel,et al.  Characterization of the aminomethylchroman derivative BAY x 3702 as a highly potent 5-hydroxytryptamine1A receptor agonist. , 1998, The Journal of pharmacology and experimental therapeutics.

[10]  J. Gidda,et al.  Pharmacological profile of LY301317, a potent and selective 5‐HT1A agonist , 1997 .

[11]  N. Matsuki,et al.  Ethanol-induced emesis in the house musk shrew, Suncus murinus. , 1996, Life sciences.

[12]  N. Matsuki,et al.  The pharmacology of the emetic response to upper gastrointestinal tract stimulation in Suncus murinus. , 1996, European journal of pharmacology.

[13]  H. Westenberg,et al.  Effects of the 5-HT1A receptor agonist flesinoxan in panic disorder , 1996, Psychopharmacology.

[14]  J. Leander,et al.  Comparison of the antiemetic effects of a 5-HT1A agonist, LY228729, and 5-HT3 antagonists in the pigeon , 1995, Pharmacology Biochemistry and Behavior.

[15]  A. Alfieri,et al.  Comparative efficacy of a single oral dose of ondansetron and of buspirone against cisplatin-induced emesis in cancer patients. , 1995, British Journal of Cancer.

[16]  J. Leander,et al.  Antiemetic effects of 5-HT1A agonists in the pigeon , 1994, Pharmacology Biochemistry and Behavior.

[17]  R. Naylor,et al.  Profiles of emetic action of cisplatin in the ferret: a potential model of acute and delayed emesis. , 1994, European journal of pharmacology.

[18]  J. Lucot Antiemetic effects of flesinoxan in cats: comparisons with 8-hydroxy-2-(di-n-propylamino)tetralin. , 1994, European journal of pharmacology.

[19]  D. Wong,et al.  Preclinical studies on LY228729: a potent and selective serotonin1A agonist. , 1993, The Journal of pharmacology and experimental therapeutics.

[20]  L. Arvidsson,et al.  Intrinsic activity of enantiomers of 8-hydroxy-2-(di-n-propylamino)tetralin and its analogs at 5-hydroxytryptamine1A receptors that are negatively coupled to adenylate cyclase. , 1991, Molecular pharmacology.

[21]  G. H. Crampton,et al.  Habituation of motion sickness in the cat. , 1991, Aviation, space, and environmental medicine.

[22]  J. Lucot Effects of serotonin antagonists on motion sickness and its suppression by 8-OH-DPAT in cats , 1990, Pharmacology Biochemistry and Behavior.

[23]  G. H. Crampton,et al.  8-OH-DPAT suppresses vomiting in the cat elicited by motion, cisplatin or xylazine , 1989, Pharmacology Biochemistry and Behavior.

[24]  J. Fozard,et al.  Antihypertensive effects of 8-hydroxy-2-(di-n-propylamino)tetralin (8-OH-DPAT) in conscious dogs. , 1988, European journal of pharmacology.

[25]  G. H. Crampton,et al.  Buspirone blocks motion sickness and xylazine-induced emesis in the cat. , 1987, Aviation, space, and environmental medicine.

[26]  G. H. Crampton,et al.  Buspirone Blocks Cisplatin‐Induced Emesis in Cats , 1987, Journal of clinical pharmacology.

[27]  G. H. Crampton,et al.  Xylazine emesis, yohimbine and motion sickness susceptibility in the cat. , 1986, The Journal of pharmacology and experimental therapeutics.

[28]  G. H. Crampton,et al.  A stimulator for laboratory studies of motion sickness in cats. , 1985, Aviation, space, and environmental medicine.

[29]  H. L. Borison,et al.  A new concept of organization of the central emetic mechanism: recent studies on the sites of action of apomorphine, copper sulfate and cardiac glycosides. , 1952, Gastroenterology.

[30]  M. Simoons,et al.  5-Hydroxytryptamine-induced contractions of the human isolated saphenous vein: involvement of 5-HT2 and 5-HT1D-like receptors, and a comparison with grafted veins , 2004, Naunyn-Schmiedeberg's Archives of Pharmacology.

[31]  N. Matsuki,et al.  Antiemetic effects of serotonergic 5-HT1A-receptor agonists in Suncus murinus. , 1994, Japanese journal of pharmacology.