CCAAT/Enhancer Binding Protein β Controls Androgen Deprivation-Induced Senescence in Prostate Cancer Cells

[1]  C. Collins,et al.  REST mediates androgen receptor actions on gene repression and predicts early recurrence of prostate cancer , 2013, Nucleic acids research.

[2]  H. Gatla,et al.  Proteasome Inhibition by Bortezomib Increases IL-8 Expression in Androgen-Independent Prostate Cancer Cells: The Role of IKKα , 2013, The Journal of Immunology.

[3]  M. Jordá,et al.  Androgen Deprivation-Induced Senescence Promotes Outgrowth of Androgen-Refractory Prostate Cancer Cells , 2013, PloS one.

[4]  Octavio A. Quiñones,et al.  C/EBPγ Suppresses Senescence and Inflammatory Gene Expression by Heterodimerizing with C/EBPβ , 2013, Molecular and Cellular Biology.

[5]  Wei Huang,et al.  Androgen deprivation induces senescence characteristics in prostate cancer cells in vitro and in vivo , 2013, The Prostate.

[6]  I. Mills,et al.  The androgen receptor induces a distinct transcriptional program in castration-resistant prostate cancer in man. , 2013, Cancer cell.

[7]  B. Sola,et al.  Senescence-associated secretory phenotype favors the emergence of cancer stem-like cells , 2012, Cell Death and Disease.

[8]  Colby G Starker,et al.  In vivo Genome Editing Using High Efficiency TALENs , 2012, Nature.

[9]  Benjamin J. Raphael,et al.  The Mutational Landscape of Lethal Castrate Resistant Prostate Cancer , 2016 .

[10]  J.,et al.  The New England Journal of Medicine , 2012 .

[11]  P. Nelson,et al.  Androgen receptor gene expression in prostate cancer is directly suppressed by the androgen receptor through recruitment of lysine-specific demethylase 1. , 2011, Cancer cell.

[12]  Erin L. Doyle,et al.  Efficient design and assembly of custom TALEN and other TAL effector-based constructs for DNA targeting , 2011, Nucleic Acids Research.

[13]  C. Galet,et al.  IGFBP-3 is a metastasis suppression gene in prostate cancer. , 2011, Cancer research.

[14]  A. Kozubík,et al.  Androgen depletion induces senescence in prostate cancer cells through down-regulation of Skp2. , 2011, Neoplasia.

[15]  T. Oka,et al.  Up-regulation of insulin-like growth factor-binding protein 3 by 5-fluorouracil (5-FU) leads to the potent anti-proliferative effect of androgen deprivation therapy combined with 5-FU in human prostate cancer cell lines. , 2011, International journal of oncology.

[16]  A. Friedman,et al.  C/ebp␣ and C/ebp␣ Oncoproteins Regulate Nfkb1 and Displace Histone Deacetylases from Nf-␬b P50 Homodimers to Induce Nf-␬b Target Genes , 2022 .

[17]  Erin L. Doyle,et al.  Efficient design and assembly of custom TALEN and other TAL effector-based constructs for DNA targeting , 2011, Nucleic acids research.

[18]  T. Oka,et al.  Hydroxyflutamide enhances cellular sensitivity to 5-fluorouracil by suppressing thymidylate synthase expression in bicalutamide-resistant human prostate cancer cells. , 2011, International journal of oncology.

[19]  A. Bradley,et al.  A hyperactive piggyBac transposase for mammalian applications , 2011, Proceedings of the National Academy of Sciences.

[20]  R. Sen,et al.  Faculty Opinions recommendation of Cell surface-bound IL-1alpha is an upstream regulator of the senescence-associated IL-6/IL-8 cytokine network. , 2010 .

[21]  R. Trumbly,et al.  C/EBPα redirects androgen receptor signaling through a unique bimodal interaction , 2010, Oncogene.

[22]  J. Campisi,et al.  The senescence-associated secretory phenotype: the dark side of tumor suppression. , 2010, Annual review of pathology.

[23]  M. Serrano,et al.  Senescence in tumours: evidence from mice and humans , 2010, Nature Reviews Cancer.

[24]  J. Campisi,et al.  Protocols to detect senescence-associated beta-galactosidase (SA-βgal) activity, a biomarker of senescent cells in culture and in vivo , 2009, Nature Protocols.

[25]  Judith Campisi,et al.  Cell surface-bound IL-1α is an upstream regulator of the senescence-associated IL-6/IL-8 cytokine network , 2009, Proceedings of the National Academy of Sciences.

[26]  Myoung H. Kim,et al.  C/EBPβ regulates metastatic gene expression and confers TNF‐α resistance to prostate cancer cells , 2009, The Prostate.

[27]  G. Coetzee,et al.  Genomic Androgen Receptor-Occupied Regions with Different Functions, Defined by Histone Acetylation, Coregulators and Transcriptional Capacity , 2008, PloS one.

[28]  D. Terrian,et al.  Senescence-associated exosome release from human prostate cancer cells. , 2008, Cancer research.

[29]  Myoung H. Kim,et al.  Translationally regulated C/EBPβ isoform expression upregulates metastatic genes in hormone‐independent prostate cancer cells , 2008, The Prostate.

[30]  D. Peeper,et al.  Oncogene-Induced Senescence Relayed by an Interleukin-Dependent Inflammatory Network , 2008, Cell.

[31]  Jonathan Melamed,et al.  Chemokine Signaling via the CXCR2 Receptor Reinforces Senescence , 2008, Cell.

[32]  P. Johnston,et al.  Interleukin-8 signaling promotes androgen-independent proliferation of prostate cancer cells via induction of androgen receptor expression and activation. , 2008, Carcinogenesis.

[33]  P. Nelson,et al.  Profiling influences of senescent and aged fibroblasts on prostate carcinogenesis , 2008, British Journal of Cancer.

[34]  A. Bergh,et al.  Increased expression of CCAAT/enhancer‐binding protein beta in proliferative inflammatory atrophy of the prostate: Relation with the expression of COX‐2, the androgen receptor, and presence of focal chronic inflammation , 2007, The Prostate.

[35]  P. Johnston,et al.  Interleukin-8 Signaling Promotes Translational Regulation of Cyclin D in Androgen-Independent Prostate Cancer Cells , 2007, Molecular Cancer Research.

[36]  T. Barrette,et al.  Oncomine 3.0: genes, pathways, and networks in a collection of 18,000 cancer gene expression profiles. , 2007, Neoplasia.

[37]  Jiaoti Huang,et al.  Expression of p14ARF, p15INK4b, p16INK4a, and DCR2 increases during prostate cancer progression , 2006, Modern Pathology.

[38]  Srinivasa R. Mantena,et al.  Control of Uterine Cell Proliferation and Differentiation by C/EBPb: Functional Implications for Establishment of Early Pregnancy , 2006, Cell cycle.

[39]  Peter F. Johnson,et al.  C/EBPbeta is a critical mediator of steroid hormone-regulated cell proliferation and differentiation in the uterine epithelium and stroma. , 2006, Proceedings of the National Academy of Sciences of the United States of America.

[40]  P. Nelson,et al.  The gene expression program of prostate fibroblast senescence modulates neoplastic epithelial cell proliferation through paracrine mechanisms. , 2006, Cancer research.

[41]  Huaitian Liu,et al.  CCAAT/Enhancer Binding Protein α (C/EBPα) and C/EBPα Myeloid Oncoproteins Induce Bcl-2 via Interaction of Their Basic Regions with Nuclear Factor-κB p50 , 2005, Molecular Cancer Research.

[42]  J. Sage,et al.  C/EBPβ cooperates with RB:E2F to implement RasV12‐induced cellular senescence , 2005 .

[43]  Huiqing Yuan,et al.  Involvement of transcription factor Sp1 in quercetin-mediated inhibitory effect on the androgen receptor in human prostate cancer cells. , 2005, Carcinogenesis.

[44]  Julien Sage,et al.  C/EBPbeta cooperates with RB:E2F to implement Ras(V12)-induced cellular senescence. , 2005, The EMBO journal.

[45]  Huaitian Liu,et al.  CCAAT/enhancer binding protein alpha (C/EBPalpha) and C/EBPalpha myeloid oncoproteins induce bcl-2 via interaction of their basic regions with nuclear factor-kappaB p50. , 2005, Molecular cancer research : MCR.

[46]  S. Lowe,et al.  Rb-Mediated Heterochromatin Formation and Silencing of E2F Target Genes during Cellular Senescence , 2003, Cell.

[47]  E. Vazquez,et al.  p21 modulates threshold of apoptosis induced by DNA-damage and growth factor withdrawal in prostate cancer cells. , 2002, Carcinogenesis.

[48]  Y. Shang,et al.  Formation of the androgen receptor transcription complex. , 2002, Molecular cell.

[49]  S. Bulun,et al.  Malignant breast epithelial cells stimulate aromatase expression via promoter II in human adipose fibroblasts: an epithelial-stromal interaction in breast tumors mediated by CCAAT/enhancer binding protein beta. , 2001, Cancer research.

[50]  R. Sutherland,et al.  Overexpression of the cell cycle inhibitor p16INK4A in high-grade prostatic intraepithelial neoplasia predicts early relapse in prostate cancer patients. , 2001, Clinical cancer research : an official journal of the American Association for Cancer Research.

[51]  M. Imagawa,et al.  Gene expression of CCAAT/enhancer-binding protein delta mediated by autoregulation is repressed by related gene family proteins. , 2000, Biological & pharmaceutical bulletin.

[52]  D. Kurz,et al.  Senescence-associated (beta)-galactosidase reflects an increase in lysosomal mass during replicative ageing of human endothelial cells. , 2000, Journal of cell science.

[53]  D. Johnson,et al.  p21WAF1 Prevents Down-modulation of the Apoptotic Inhibitor Protein c-IAP1 and Inhibits Leukemic Apoptosis , 2000, Molecular medicine.

[54]  A. Leutz,et al.  Translational control of C/EBPalpha and C/EBPbeta isoform expression. , 2000, Genes & development.

[55]  G. Jenster,et al.  Androgen induction of cyclin-dependent kinase inhibitor p21 gene: role of androgen receptor and transcription factor Sp1 complex. , 2000, Molecular endocrinology.

[56]  A. Welm,et al.  CUG repeat binding protein (CUGBP1) interacts with the 5'''' region of C/EBPβ β β β mRNA and regulates translation of C/EBPβ , 1999 .

[57]  P. Johnson,et al.  CCAAT/Enhancer-binding Proteins Regulate Expression of the Human Steroidogenic Acute Regulatory Protein (StAR) Gene* , 1999, The Journal of Biological Chemistry.

[58]  E. Scott,et al.  C/EBP Bypasses Granulocyte Colony-Stimulating Factor Signals to Rapidly Induce PU.1 Gene Expression, Stimulate Granulocytic Differentiation, and Limit Proliferation in 32D cl3 Myeloblasts , 1999 .

[59]  C. Cordon-Cardo,et al.  Overexpression of the cyclin-dependent kinase inhibitor p16 is associated with tumor recurrence in human prostate cancer. , 1999, Clinical cancer research : an official journal of the American Association for Cancer Research.

[60]  G. Baretton,et al.  Proliferation- and apoptosis-associated factors in advanced prostatic carcinomas before and after androgen deprivation therapy: prognostic significance of p21/WAF1/CIP1 expression , 1999, British Journal of Cancer.

[61]  C. Sawyers,et al.  C/EBPalpha bypasses granulocyte colony-stimulating factor signals to rapidly induce PU.1 gene expression, stimulate granulocytic differentiation, and limit proliferation in 32D cl3 myeloblasts. , 1999, Blood.

[62]  A. Welm,et al.  CUG repeat binding protein (CUGBP1) interacts with the 5' region of C/EBPbeta mRNA and regulates translation of C/EBPbeta isoforms. , 1999, Nucleic acids research.

[63]  R. Haché,et al.  AF-2-dependent potentiation of CCAAT enhancer binding protein beta-mediated transcriptional activation by glucocorticoid receptor. , 1998, Molecular endocrinology.

[64]  J. Isaacs,et al.  Role of programmed (apoptotic) cell death during the progression and therapy for prostate cancer , 1996, The Prostate.

[65]  J. Isaacs,et al.  Activation of programmed (apoptotic) cell death for the treatment of prostate cancer. , 1996, Advances in pharmacology.

[66]  B Stein,et al.  Repression of the interleukin-6 promoter by estrogen receptor is mediated by NF-kappa B and C/EBP beta , 1995, Molecular and cellular biology.

[67]  T. Guthrie,et al.  Prostate cancer. , 2020, American family physician.

[68]  Y. Oshika,et al.  P-glycoprotein-mediated acquired multidrug resistance of human lung cancer cells in vivo. , 1996, British Journal of Cancer.

[69]  U. G. Dailey.  Cancer,Facts and Figures about. , 2022, Journal of the National Medical Association.