Chromosome survey of new patients admitted to the four maximum security hospitals in the United Kingdom

In a survey of male patients admitted to the four maximum security hospitals in the United Kingdom during 1972 and 1973, 26 out of 611 (4.26 %) karyotyped were found to have chromosome abnormalities. Of these, 13 (2.13 %) had a 47,XYY abnormality; 5 (0.8 %) were chromatin positive but two of these had cell lines that included an extra Y chromosome, one being a 48,XXYY male and the other a mosaic 48,XXYY/47,XYY. Eight patients with autosomal abnormalities included two with Down's syndrome and a 47,XY,+21 karyotype, two with small supernumerary chromosomes, 47,XY + mar, and two with inherited balanced translocation.

[1]  I. Lauder,et al.  The electrocardiogram and sex chromosome aneuploidy , 1974, Clinical genetics.

[2]  I. Lauder,et al.  Anthropometry in sex chromosome abnormality , 1974, Clinical genetics.

[3]  E. Hook.  Behavioral implications of the human XYY genotype. , 1973, Science.

[4]  C. Blank,et al.  Male patients with chromosome abnormality in two State hospitals. , 2008, Journal of mental deficiency research.

[5]  J. Nielsen.  Prevalence and a 2½ Years Incidence of Chromosome Abnormalities Among all Males in a Forensic Psychiatric Clinic , 1971, British Journal of Psychiatry.

[6]  H. Zellweger,et al.  The syndrome of the metacentric microchromosome. , 1970, Helvetica paediatrica acta.

[7]  J. Nielsen,et al.  PREVALENCE AND INCIDENCE OF THE XYY SYNDROME AND KLINEFELTER'S SYNDROME I N AN INSTITUTION FOR CRIMINAL PSYCHO PATHS , 1969 .

[8]  J. Nielsen,et al.  PREVALENCE OF THE XYY SYNDROME I N AN INSTITUTION FOR PSYCHOLOGICALLY ABN 0 RMAL CRIMINALS , 1969, Acta psychiatrica Scandinavica.

[9]  R. Daly.  Neurological Abnormalities in XYY Males , 1969, Nature.

[10]  W. M. Court-Brown,et al.  Human population cytogenetics. , 1969, British medical bulletin.

[11]  W. Price.  The electrocardiogram in males with extra Y chromosomes. , 1968, Lancet.

[12]  P. Jacobs,et al.  Chromosome studies on men in a Maximum Security Hospital , 1968 .

[13]  C. Blank,et al.  YY CHROMOSOMES AND ANTISOCIAL BEHAVIOUR , 1966 .

[14]  J. A. Strong,et al.  Criminal patients with XYY sex-chromosome complement. , 1966, Lancet.

[15]  M. Fraccaro,et al.  CHROMOSOMES IN COLOBOMA AND ANAL ATRESIA. , 1965, Lancet.

[16]  J. Pearce.  The Primitive Catatonic Psychosis of Idiocy. (Brit. Journ. Med. Psych., vol. xiv, p. 230, Oct., 1934.) Earl, C. J. C. , 1935 .

[17]  C. Earl.  THE PRIMITIVE CATATONIC PSYCHOSIS OF IDIOCY1 , 1934 .