A systematic approach to vaccine complexity using an automaton model of the cellular and humoral immune system. I. Viral characteristics and polarized responses.

[1]  Stefania Gallucci,et al.  Natural adjuvants: Endogenous activators of dendritic cells , 1999, Nature Medicine.

[2]  F. Sallusto,et al.  Two subsets of memory T lymphocytes with distinct homing potentials and effector functions , 1999, Nature.

[3]  N. Sheikh,et al.  Novel aggregate structure adjuvants modulate lymphocyte proliferation and Th1 and Th2 cytokine profiles in ovalbumin immunized mice. , 1999, Vaccine.

[4]  N. Kadowaki,et al.  Reciprocal control of T helper cell and dendritic cell differentiation. , 1999, Science.

[5]  T. Baldwin,et al.  Vaccination with recombinant Parasite Surface Antigen 2 from Leishmania major induces a Th1 type of immune response but does not protect against infection. , 1998, Vaccine.

[6]  Franco Celada,et al.  Modeling immune cognition , 1998, SMC'98 Conference Proceedings. 1998 IEEE International Conference on Systems, Man, and Cybernetics (Cat. No.98CH36218).

[7]  J. Haddad,et al.  Humoral and cell-mediated immunopotentiation in vaccinated chicken layers by thymic hormones and zinc. , 1998, Vaccine.

[8]  R. Murray,et al.  Vaccination with glutaraldehyde-fixed bovine respiratory syncytial virus (BRSV)-infected cells stimulates a better immune response in lambs than vaccination with heat-inactivated cell-free BRSV. , 1998, Vaccine.

[9]  S. Constant,et al.  Strength of TCR signal determines the costimulatory requirements for Th1 and Th2 CD4+ T cell differentiation. , 1997, Journal of immunology.

[10]  G. Weisbuch,et al.  Immunology for physicists , 1997 .

[11]  P E Seiden,et al.  A solution to the rheumatoid factor paradox: pathologic rheumatoid factors can be tolerized by competition with natural rheumatoid factors. , 1997, Journal of immunology.

[12]  R. Zinkernagel,et al.  Neutralizing antiviral B cell responses. , 1997, Annual review of immunology.

[13]  Franco Celada,et al.  Affinity maturation and hypermutation in a simulation of the humoral immune response , 1996, European journal of immunology.

[14]  R. Brines.  Two hundred years on: Jenner and the discovery of vaccination. , 1996, Immunology today.

[15]  Rolf M. Zinkernagel,et al.  Immunology Taught by Viruses , 1996, Science.

[16]  P E Seiden,et al.  Modelling thymic functions in a cellular automaton. , 1995, International immunology.

[17]  B. Golding,et al.  The potential for recruiting immune responses toward type 1 or type 2 T cell help. , 1994, The American journal of tropical medicine and hygiene.

[18]  R. Rappuoli.  Toxin inactivation and antigen stabilization: two different uses of formaldehyde. , 1994, Vaccine.

[19]  P. Matzinger.  Tolerance, danger, and the extended family. , 1994, Annual review of immunology.

[20]  P E Seiden,et al.  A model for simulating cognate recognition and response in the immune system. , 1992, Journal of theoretical biology.

[21]  Jacek Waniewski,et al.  Mathematical Modeling of the Immune Response , 1992 .

[22]  P E Seiden,et al.  A computer model of cellular interactions in the immune system. , 1992, Immunology today.

[23]  D. Gray,et al.  Population kinetics of rat peripheral B cells , 1988, The Journal of experimental medicine.

[24]  A. McMichael,et al.  Cytotoxic T-cell immunity to influenza. , 1983, The New England journal of medicine.

[25]  E. Unanue.  The regulatory role of macrophages in antigenic stimulation. Part Two: symbiotic relationship between lymphocytes and macrophages. , 1981, Advances in immunology.

[26]  J. Sissons,et al.  Antibody-Mediated Destruction of Virus-Infected Cells , 1980, Advances in Immunology.

[27]  F Celada,et al.  The cellular basis of immunologic memory. , 1971, Progress in allergy.