Multimodal exercise intervention improves frontal cognitive functions and gait in Alzheimer's disease: A controlled trial

Aim:  The objective of the present study was to investigate the effect of a multimodal exercise intervention on frontal cognitive functions and kinematic gait parameters in patients with Alzheimer's disease.

[1]  D. Royall,et al.  The FAB: A frontal assessment battery at bedside , 2001, Neurology.

[2]  E. Scherder,et al.  Exercise, cognition and Alzheimer's disease: More is not necessarily better , 2006, Neuroscience & Biobehavioral Reviews.

[3]  S. Gobbi,et al.  Atividade física sistematizada e desempenho cognitivo em idosos com demência de Alzheimer: uma revisão sistemática , 2009 .

[4]  G. Salem,et al.  American College of Sports Medicine position stand. Exercise and physical activity for older adults. , 2009, Medicine and science in sports and exercise.

[5]  M. Woollacott,et al.  Attention and the control of posture and gait: a review of an emerging area of research. , 2002, Gait & posture.

[6]  G. Sorrentino,et al.  Biological Mechanisms of Physical Activity in Preventing Cognitive Decline , 2010, Cellular and Molecular Neurobiology.

[7]  S. Folstein,et al.  "Mini-mental state". A practical method for grading the cognitive state of patients for the clinician. , 1975, Journal of psychiatric research.

[8]  P. Heyn.  The effect of a multisensory exercise program on engagement, behavior, and selected physiological indexes in persons with dementia , 2003, American journal of Alzheimer's disease and other dementias.

[9]  I Litvan,et al.  The FAB: A frontal assessment battery at bedside , 2000, Neurology.

[10]  E. Salmon,et al.  Gait analysis in elderly adult patients with mild cognitive impairment and patients with mild Alzheimer’s disease: simple versus dual task: a preliminary report , 2010, Clinical physiology and functional imaging.

[11]  Xiaonan Xue,et al.  Quantitative gait dysfunction and risk of cognitive decline and dementia , 2007, Journal of Neurology, Neurosurgery & Psychiatry.

[12]  V. Leirer,et al.  Development and validation of a geriatric depression screening scale: a preliminary report. , 1982, Journal of psychiatric research.

[13]  Jeffrey M. Hausdorff,et al.  The Role of Higher-Level Cognitive Function in Gait: Executive Dysfunction Contributes to Fall Risk in Alzheimer’s Disease , 2007, Dementia and Geriatric Cognitive Disorders.

[14]  Xiaonan Xue,et al.  Cognitive processes related to gait velocity: results from the Einstein Aging Study. , 2006, Neuropsychology.

[15]  R. Nitrini,et al.  Brazilian version of the Frontal Assessment Battery (FAB): Preliminary data on administration to healthy elderly , 2007, Dementia & neuropsychologia.

[16]  S. Gobbi,et al.  Efeitos de um programa de atividade física nas funções cognitivas, equilíbrio e risco de quedas em idosos com demência de Alzheimer , 2010 .

[17]  P. Thompson,et al.  Progressive frontal gait disturbance with atypical Alzheimer’s disease and corticobasal degeneration , 1999, Journal of neurology, neurosurgery, and psychiatry.

[18]  Jeffrey M. Hausdorff,et al.  Influence of Executive Function on Locomotor Function: Divided Attention Increases Gait Variability in Alzheimer's Disease , 2003, Journal of the American Geriatrics Society.

[19]  A. Schultz,et al.  Maintenance of balance, gait patterns, and obstacle clearance in Alzheimer's disease , 1995, Neurology.

[20]  Jeffrey M. Hausdorff,et al.  Dual‐tasking effects on gait variability: The role of aging, falls, and executive function , 2006, Movement disorders : official journal of the Movement Disorder Society.

[21]  A M Jette,et al.  Moderate exercise improves gait stability in disabled elders. , 1998, Archives of physical medicine and rehabilitation.

[22]  G. Borm,et al.  The effect of cognitive dual tasks on balance during walking in physically fit elderly people. , 2007, Archives of physical medicine and rehabilitation.

[23]  Sharon Arkin,et al.  Language-Enriched Exercise Plus Socialization Slows Cognitive Decline in Alzheimer’s Disease , 2007, American journal of Alzheimer's disease and other dementias.

[24]  Olivier Beauchet,et al.  Changes in gait while backward counting in demented older adults with frontal lobe dysfunction. , 2007, Gait & posture.

[25]  J. Judge,et al.  Exercise to improve gait velocity in older persons. , 1993, Archives of physical medicine and rehabilitation.

[26]  E. Walker,et al.  Diagnostic and Statistical Manual of Mental Disorders , 2013 .

[27]  José Luiz Riani Costa,et al.  Gait and risk of falls associated with frontal cognitive functions at different stages of Alzheimer's disease , 2012, Neuropsychology, development, and cognition. Section B, Aging, neuropsychology and cognition.

[28]  Jeffrey M. Hausdorff,et al.  The role of executive function and attention in gait , 2008, Movement disorders : official journal of the Movement Disorder Society.

[29]  R H Logie,et al.  Dual task effects of walking when talking in Alzheimer's disease. , 2004, Revue neurologique.

[30]  J. Grafman,et al.  Clock Drawing in Alzheimer's Disease , 1989, Journal of the American Geriatrics Society.

[31]  P. Eslinger,et al.  Improving cognition and function through exercise intervention in Alzheimer's disease. , 2006, Journal of nursing scholarship : an official publication of Sigma Theta Tau International Honor Society of Nursing.

[32]  Sebastião Gobbi,et al.  [Systematized physical activity and cognitive performance in elderly with Alzheimer's dementia: a systematic review]. , 2009, Revista brasileira de psiquiatria.

[33]  R. Tappen,et al.  The Effect of Planned Walking on Communication in Alzheimer's Disease , 1991, Journal of the American Geriatrics Society.

[34]  G. Jarnlo,et al.  Lower Gait Speed in Older Women with Dementia Compared with Controls , 2005, Dementia and Geriatric Cognitive Disorders.

[35]  Arthur F. Kramer,et al.  Capitalizing on cortical plasticity: influence of physical activity on cognition and brain function , 2007, Trends in Cognitive Sciences.

[36]  F. Stella,et al.  [Effects of physical activity on cognitive functions, balance and risk of falls in elderly patients with Alzheimer's dementia]. , 2010, Revista brasileira de fisioterapia (Sao Carlos (Sao Paulo, Brazil)).