Organic synthesis with enzymes in non-aqueous media
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Introduction (G. Carrea and S. Riva) PART I: BIOCATALYSIS IN NEAT ORGANIC SOLVENTS - FUNDAMENTALS Fundamentals of biocatalysis in neat organic solvents (Patrick Adlercreutz) Effects of organic solvents on enzyme selectivity (Jaap Jongejan) Activating enzymes for use in organic solvents (Anne Serdakowski and Jonathan Dordick) PART II: BIOCATALYSIS IN NEAT ORGANIC SOLVENTS - SYNTHETIC APPLICATIONS Exploiting enantioselectivity of hydrolases in organic solvents (Hans-Erik Hogberg) Enzymatic dynamic kinetic resolution processes (Jan Backvall) Exploiting enzyme regioselectivity and chemoselectivity (Sergio Riva) Industrial scale applications of enzymes in non aqueous solvents (David Pollard and Birgit Kosjek) PART III: BIOCATALYSIS IN BIPHASIC AND NEW REACTION MEDIA Biocatalysis in biphasic systems: general (Pedro Fernandes and Joaquim Cabral) Biocatalysis in biphasic systems: oxynitrilases (Manuela Avi and Herfried Griengl Ionic liquids as media for enzymatic transformations (Roger Sheldon and Fred van Rantwijk) Solid/gas biocatalysis (Isabelle Goubet, Marianne Graber, Sylvain Lamare, Thierry Maugard and Marie-Dominique Legoy) Biocatalysis with undissolved solid substrates and products (Alessandra Basso, Sara Cantone, Cynthia Ebert, Peter Halling and Lucia Gardossi)