The RECAP Test Rapidly and Reliably Identifies Homologous Recombination-Deficient Ovarian Carcinomas
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T. van Wezel | T. Bosse | H. Vrieling | D. V. van Gent | N. T. Ter Haar | Lise M van Wijk | K. Gaarenstroom | M. Vreeswijk | J. Kroep | N. Solleveld-Westerink | M. Meijers | S. Vermeulen | M. M. de Jonge | Manuela F van Diest | M. V. van Diest
[1] F. Marmé,et al. Olaparib plus Bevacizumab as First-Line Maintenance in Ovarian Cancer. , 2019, The New England journal of medicine.
[2] B. Monk,et al. Niraparib in Patients with Newly Diagnosed Advanced Ovarian Cancer. , 2019, The New England journal of medicine.
[3] M. Morgan,et al. Veliparib with First-Line Chemotherapy and as Maintenance Therapy in Ovarian Cancer. , 2019, The New England journal of medicine.
[4] Lauren L. Ritterhouse,et al. Germline BRCA-Associated Endometrial Carcinoma Is a Distinct Clinicopathologic Entity , 2019, Clinical Cancer Research.
[5] L. Saal,et al. Whole-genome-sequencing of triple negative breast cancers in a population-based clinical study , 2019, Nature Medicine.
[6] J. Ledermann,et al. ESGO consensus conference recommendations on ovarian cancer : pathology and molecular biology , early and advanced stages , borderline tumours and recurrent disease , 2019 .
[7] A. Jager,et al. Direct Ex Vivo Observation of Homologous Recombination Defect Reversal After DNA-Damaging Chemotherapy in Patients With Metastatic Breast Cancer. , 2019, JCO precision oncology.
[8] A. Oza,et al. Epithelial ovarian cancer , 2019, The Lancet.
[9] D. G. Evans,et al. Epithelial ovarian cancer risk: A review of the current genetic landscape , 2019, Clinical genetics.
[10] B. Job,et al. Frequent Homologous Recombination Deficiency in High-grade Endometrial Carcinomas , 2018, Clinical Cancer Research.
[11] C. Caldas,et al. A RAD51 assay feasible in routine tumor samples calls PARP inhibitor response beyond BRCA mutation , 2018, EMBO molecular medicine.
[12] Gabe S. Sonke,et al. Maintenance Olaparib in Patients with Newly Diagnosed Advanced Ovarian Cancer , 2018, The New England journal of medicine.
[13] D. Matei,et al. Long-term efficacy, tolerability and overall survival in patients with platinum-sensitive, recurrent high-grade serous ovarian cancer treated with maintenance olaparib capsules following response to chemotherapy , 2018, British Journal of Cancer.
[14] Sarah Keegan,et al. Spatiotemporal dynamics of homologous recombination repair at single collapsed replication forks , 2018, Nature Communications.
[15] C. V. van Asperen,et al. Validation and Implementation of BRCA1/2 Variant Screening in Ovarian Tumor Tissue. , 2018, The Journal of molecular diagnostics : JMD.
[16] A. Sieuwerts,et al. Functional Ex Vivo Assay Reveals Homologous Recombination Deficiency in Breast Cancer Beyond BRCA Gene Defects , 2018, Clinical Cancer Research.
[17] L. Kauppi,et al. A Functional Homologous Recombination Assay Predicts Primary Chemotherapy Response and Long-Term Survival in Ovarian Cancer Patients , 2018, Clinical Cancer Research.
[18] A. Jemal,et al. Ovarian cancer statistics, 2018 , 2018, CA: a cancer journal for clinicians.
[19] P. Kristel,et al. RAD51 foci as a functional biomarker of homologous recombination repair and PARP inhibitor resistance in germline BRCA-mutated breast cancer , 2018, Annals of oncology : official journal of the European Society for Medical Oncology.
[20] James X. Sun,et al. Rucaparib maintenance treatment for recurrent ovarian carcinoma after response to platinum therapy (ARIEL3): a randomised, double-blind, placebo-controlled, phase 3 trial , 2017, The Lancet.
[21] Val Gebski,et al. Olaparib tablets as maintenance therapy in patients with platinum-sensitive, relapsed ovarian cancer and a BRCA1/2 mutation (SOLO2/ENGOT-Ov21): a double-blind, randomised, placebo-controlled, phase 3 trial. , 2017, The Lancet. Oncology.
[22] E. Birney,et al. HRDetect is a predictor of BRCA1 and BRCA2 deficiency based on mutational signatures , 2017, Nature Medicine.
[23] Kenneth D. Doig,et al. Reversion of BRCA1/2 Germline Mutations Detected in Circulating Tumor DNA From Patients With High-Grade Serous Ovarian Cancer. , 2017, Journal of clinical oncology : official journal of the American Society of Clinical Oncology.
[24] Ignace Vergote,et al. Niraparib Maintenance Therapy in Platinum-Sensitive, Recurrent Ovarian Cancer. , 2016, The New England journal of medicine.
[25] Yu Zhang,et al. TP53 mutations in epithelial ovarian cancer. , 2016, Translational cancer research.
[26] Erich P Huang,et al. RECIST 1.1-Update and clarification: From the RECIST committee. , 2016, European journal of cancer.
[27] G. Shapiro,et al. Homologous Recombination Deficiency: Exploiting the Fundamental Vulnerability of Ovarian Cancer. , 2015, Cancer discovery.
[28] B. Gilks,et al. Candidate biomarkers of PARP inhibitor sensitivity in ovarian cancer beyond the BRCA genes , 2015, British Journal of Cancer.
[29] Joshy George,et al. Whole–genome characterization of chemoresistant ovarian cancer , 2015, Nature.
[30] Nicolai J. Birkbak,et al. Pan-cancer analysis of genomic scar signatures associated with homologous recombination deficiency suggests novel indications for existing cancer drugs , 2015, Biomarker Research.
[31] Alexander Gutin,et al. Association of BRCA1/2defects with genomic scores predictive of DNA damage repair deficiency among breast cancer subtypes , 2014, Breast Cancer Research.
[32] E. Yang,et al. An ex vivo assay of XRT-induced Rad51 foci formation predicts response to PARP-inhibition in ovarian cancer. , 2014, Gynecologic oncology.
[33] R. Zeillinger,et al. BRCA1 gene promoter methylation status in high-grade serous ovarian cancer patients--a study of the tumour Bank ovarian cancer (TOC) and ovarian cancer diagnosis consortium (OVCAD). , 2014, European journal of cancer.
[34] Jianping Lu,et al. Correlation between gene expression and mutator phenotype predicts homologous recombination deficiency and outcome in ovarian cancer , 2014, Journal of Molecular Medicine.
[35] A. Sieuwerts,et al. Functional Ex Vivo Assay to Select Homologous Recombination–Deficient Breast Tumors for PARP Inhibitor Treatment , 2014, Clinical Cancer Research.
[36] N. Curtin,et al. Assessing the function of homologous recombination DNA repair in malignant pleural effusion (MPE) samples , 2014, British Journal of Cancer.
[37] Benjamin J. Raphael,et al. Integrated Analysis of Germline and Somatic Variants in Ovarian Cancer , 2014, Nature Communications.
[38] Jaime Prat,et al. Staging classification for cancer of the ovary, fallopian tube, and peritoneum , 2014, International journal of gynaecology and obstetrics: the official organ of the International Federation of Gynaecology and Obstetrics.
[39] Zoltan Szallasi,et al. Tumor Mutation Burden Forecasts Outcome in Ovarian Cancer with BRCA1 or BRCA2 Mutations , 2013, PloS one.
[40] P. Maxwell,et al. Clinicopathological features of homologous recombination-deficient epithelial ovarian cancers: sensitivity to PARP inhibitors, platinum, and survival. , 2012, Cancer research.
[41] A. Vincent-Salomon,et al. Ploidy and large-scale genomic instability consistently identify basal-like breast carcinomas with BRCA1/2 inactivation. , 2012, Cancer research.
[42] G. Mills,et al. Patterns of genomic loss of heterozygosity predict homologous recombination repair defects in epithelial ovarian cancer , 2012, British Journal of Cancer.
[43] The Cancer Genome Atlas Research Network. Erratum: Integrated genomic analyses of ovarian carcinoma , 2012, Nature.
[44] D. Matei,et al. Olaparib maintenance therapy in platinum-sensitive relapsed ovarian cancer. , 2012, The New England journal of medicine.
[45] Rochelle L. Garcia,et al. Mutations in 12 genes for inherited ovarian, fallopian tube, and peritoneal carcinoma identified by massively parallel sequencing , 2011, Proceedings of the National Academy of Sciences.
[46] Rochelle L. Garcia,et al. Secondary somatic mutations restoring BRCA1/2 predict chemotherapy resistance in hereditary ovarian carcinomas. , 2011, Journal of clinical oncology : official journal of the American Society of Clinical Oncology.
[47] Benjamin J. Raphael,et al. Integrated Genomic Analyses of Ovarian Carcinoma , 2011, Nature.
[48] Corneel Coens,et al. Early versus delayed treatment of relapsed ovarian cancer (MRC OV05/EORTC 55955): a randomised trial , 2010, The Lancet.
[49] A. Ashworth,et al. A Marker of Homologous Recombination Predicts Pathologic Complete Response to Neoadjuvant Chemotherapy in Primary Breast Cancer , 2010, Clinical Cancer Research.
[50] Y. Drew,et al. Development of a Functional Assay for Homologous Recombination Status in Primary Cultures of Epithelial Ovarian Tumor and Correlation with Sensitivity to Poly(ADP-Ribose) Polymerase Inhibitors , 2010, Clinical Cancer Research.
[51] D. Sgroi,et al. Utility of DNA Repair Protein Foci for the Detection of Putative BRCA1 Pathway Defects in Breast Cancer Biopsies , 2009, Molecular Cancer Research.
[52] A. Spurdle,et al. Sequence variant classification and reporting: recommendations for improving the interpretation of cancer susceptibility genetic test results , 2008, Human mutation.
[53] F. Couch,et al. Secondary mutations as a mechanism of cisplatin resistance in BRCA2-mutated cancers , 2008, Nature.
[54] Anne Floquet,et al. Rucaparib in relapsed, platinum-sensitive high-grade ovarian carcinoma (ARIEL2 Part 1): an international, multicentre, open-label, phase 2 trial. , 2017, The Lancet. Oncology.