β-Arrestin prevents cell apoptosis through pro-apoptotic ERK1/2 and p38 MAPKs and anti-apoptotic Akt pathways

[1]  A. Lymperopoulos,et al.  Pharmacogenomics of the heptahelical receptor regulators G-protein-coupled receptor kinases and arrestins: the known and the unknown. , 2012, Pharmacogenomics.

[2]  Xueqiao Liu,et al.  Varicella-Zoster Virus ORF12 Protein Triggers Phosphorylation of ERK1/2 and Inhibits Apoptosis , 2012, Journal of Virology.

[3]  J. Miao,et al.  Toll-Like Receptor 9 Is Required for Opioid-Induced Microglia Apoptosis , 2011, PloS one.

[4]  Z. Chi,et al.  Glycogen synthase kinase-3 and p38 MAPK are required for opioid-induced microglia apoptosis , 2010, Neuropharmacology.

[5]  Lihui Wei,et al.  Beta-arrestin 2 modulates resveratrol-induced apoptosis and regulation of Akt/GSK3ß pathways. , 2010, Biochimica et biophysica acta.

[6]  J. Chambard,et al.  ERK and cell death: Mechanisms of ERK‐induced cell death – apoptosis, autophagy and senescence , 2010, The FEBS journal.

[7]  R. Lefkowitz,et al.  Arrestin development: emerging roles for beta-arrestins in developmental signaling pathways. , 2009, Developmental cell.

[8]  R. Lefkowitz,et al.  β-Arrestin-2 Mediates Anti-apoptotic Signaling through Regulation of BAD Phosphorylation , 2009, Journal of Biological Chemistry.

[9]  D. Yin,et al.  Morphine promotes apoptosis via TLR2, and this is negatively regulated by beta-arrestin 2. , 2009, Biochemical and biophysical research communications.

[10]  K. Roth,et al.  Neural Precursor Cells Are Protected from Apoptosis Induced by Trophic Factor Withdrawal or Genotoxic Stress by Inhibitors of Glycogen Synthase Kinase 3* , 2007, Journal of Biological Chemistry.

[11]  R. Gainetdinov,et al.  The Akt-GSK-3 signaling cascade in the actions of dopamine. , 2007, Trends in pharmacological sciences.

[12]  S. Milano,et al.  Regulation of receptor trafficking by GRKs and arrestins. , 2007, Annual review of physiology.

[13]  Lan Ma,et al.  β-arrestin signaling and regulation of transcription , 2007, Journal of Cell Science.

[14]  R. DuBois,et al.  Emerging Roles of β-Arrestins , 2006 .

[15]  J. Blenis,et al.  MAPK signal specificity: the right place at the right time. , 2006, Trends in biochemical sciences.

[16]  M. Woodruff,et al.  Morphine promotes Jurkat cell apoptosis through pro-apoptotic FADD/P53 and anti-apoptotic PI3K/Akt/NF-κB pathways , 2006, Journal of Neuroimmunology.

[17]  Eric Reiter,et al.  GRKs and β-arrestins: roles in receptor silencing, trafficking and signaling , 2006, Trends in Endocrinology & Metabolism.

[18]  K. Al-Kuraya,et al.  JAK Family of Tyrosine Kinases: Its Functions and Alterations in Human Cancer , 2006 .

[19]  Jiuhong Kang,et al.  β‐Arrestin2 functions as a phosphorylation‐regulated suppressor of UV‐induced NF‐κB activation , 2005 .

[20]  T. Sotnikova,et al.  An Akt/β-Arrestin 2/PP2A Signaling Complex Mediates Dopaminergic Neurotransmission and Behavior , 2005, Cell.

[21]  M. Oshimura,et al.  PI3K-Akt pathway: Its functions and alterations in human cancer , 2004, Apoptosis.

[22]  G. Geisslinger,et al.  Opioids As Modulators of Cell Death and Survival—Unraveling Mechanisms and Revealing New Indications , 2004, Pharmacological Reviews.

[23]  D. Cimino,et al.  Arrestins Block G Protein-coupled Receptor-mediated Apoptosis* , 2004, Journal of Biological Chemistry.

[24]  T. Kohout,et al.  β-Arrestin1 Mediates Insulin-like Growth Factor 1 (IGF-1) Activation of Phosphatidylinositol 3-Kinase (PI3K) and Anti-apoptosis* , 2003, Journal of Biological Chemistry.

[25]  M. Benito,et al.  P38 alpha mitogen-activated protein kinase sensitizes cells to apoptosis induced by different stimuli. , 2003, Molecular biology of the cell.

[26]  Ping Wang,et al.  β-Arrestin 2 Functions as a G-Protein-coupled Receptor-activated Regulator of Oncoprotein Mdm2* , 2003, The Journal of Biological Chemistry.

[27]  T. Mak,et al.  ERK Activation Mediates Cell Cycle Arrest and Apoptosis after DNA Damage Independently of p53* , 2002, The Journal of Biological Chemistry.

[28]  P. Kang,et al.  Direct Activation of Mitochondrial Apoptosis Machinery by c-Jun N-terminal Kinase in Adult Cardiac Myocytes* , 2002, The Journal of Biological Chemistry.

[29]  J. Woodgett,et al.  PKB/AKT: functional insights from genetic models , 2001, Nature Reviews Molecular Cell Biology.

[30]  G. D. De Zutter,et al.  Pro-apoptotic gene expression mediated by the p38 mitogen-activated protein kinase signal transduction pathway , 2001, Proceedings of the National Academy of Sciences of the United States of America.

[31]  M. Cobb,et al.  Mitogen-activated protein (MAP) kinase pathways: regulation and physiological functions. , 2001, Endocrine reviews.

[32]  M. Karin,et al.  Mammalian MAP kinase signalling cascades , 2001, Nature.

[33]  D. Kimelman,et al.  Role of Glycogen Synthase Kinase-3β in Neuronal Apoptosis Induced by Trophic Withdrawal , 2000, The Journal of Neuroscience.

[34]  H. Ichijo,et al.  From receptors to stress-activated MAP kinases , 1999, Oncogene.

[35]  Jacques Landry,et al.  SAPK2/p38-dependent F-Actin Reorganization Regulates Early Membrane Blebbing during Stress-induced Apoptosis , 1998, The Journal of cell biology.

[36]  N. Holbrook,et al.  The cellular response to oxidative stress: influences of mitogen-activated protein kinase signalling pathways on cell survival. , 1998, The Biochemical journal.

[37]  A. Lymperopoulos Beta-arrestin biased agonism/antagonism at cardiovascular seven transmembrane-spanning receptors. , 2012, Current pharmaceutical design.

[38]  Ying Zhang,et al.  Toll-like receptor 2 is required for opioids-induced neuronal apoptosis. , 2010, Biochemical and biophysical research communications.

[39]  R. DuBois,et al.  Emerging roles of beta-arrestins. , 2006, Cell cycle.

[40]  Eric Reiter,et al.  GRKs and beta-arrestins: roles in receptor silencing, trafficking and signaling. , 2006, Trends in endocrinology and metabolism: TEM.

[41]  Jiuhong Kang,et al.  Beta-arrestin2 functions as a phosphorylation-regulated suppressor of UV-induced NF-kappaB activation. , 2005, The EMBO journal.