Longitudinal Change Detection on Chest X-rays Using Geometric Correlation Maps

The diagnostic decision for chest X-ray image generally considers a probable change in a lesion, compared to the previous examination. We propose a novel algorithm to detect the change in longitudinal chest X-ray images. We extract feature maps from a pair of input images through two streams of convolutional neural networks. Next we generate the geometric correlation map computing matching scores for every possible match of local descriptors in two feature maps. This correlation map is fed into a binary classifier to detect specific patterns of the map representing the change in the lesion. Since no public dataset offers proper information to train the proposed network, we also build our own dataset by analyzing reports in examinations at a tertiary hospital. Experimental results show our approach outperforms previous methods in quantitative comparison. We also provide various case examples visualizing the effect of the proposed geometric correlation map.

[1]  Josef Sivic,et al.  Convolutional Neural Network Architecture for Geometric Matching , 2019, IEEE Transactions on Pattern Analysis and Machine Intelligence.

[2]  Gang Sun,et al.  Squeeze-and-Excitation Networks , 2017, 2018 IEEE/CVF Conference on Computer Vision and Pattern Recognition.

[3]  P. Lakhani,et al.  Deep Learning at Chest Radiography: Automated Classification of Pulmonary Tuberculosis by Using Convolutional Neural Networks. , 2017, Radiology.

[4]  Bram van Ginneken,et al.  Pulmonary Nodule Detection in CT Images: False Positive Reduction Using Multi-View Convolutional Networks , 2016, IEEE Transactions on Medical Imaging.

[5]  Giovanni Montana,et al.  Longitudinal detection of radiological abnormalities with time-modulated LSTM , 2018, DLMIA/ML-CDS@MICCAI.

[6]  Tomas Mikolov,et al.  Bag of Tricks for Efficient Text Classification , 2016, EACL.

[7]  Stefan Jaeger,et al.  Two public chest X-ray datasets for computer-aided screening of pulmonary diseases. , 2014, Quantitative imaging in medicine and surgery.

[8]  Josef Sivic,et al.  End-to-End Weakly-Supervised Semantic Alignment , 2017, 2018 IEEE/CVF Conference on Computer Vision and Pattern Recognition.

[9]  Eui Jin Hwang,et al.  Development and Validation of Deep Learning-based Automatic Detection Algorithm for Malignant Pulmonary Nodules on Chest Radiographs. , 2019, Radiology.

[10]  Abhinav Gupta,et al.  Non-local Neural Networks , 2017, 2018 IEEE/CVF Conference on Computer Vision and Pattern Recognition.

[11]  Ramandeep Singh,et al.  Deep learning in chest radiography: Detection of findings and presence of change , 2018, PloS one.

[12]  Yifan Yu,et al.  CheXpert: A Large Chest Radiograph Dataset with Uncertainty Labels and Expert Comparison , 2019, AAAI.

[13]  Ronald M. Summers,et al.  ChestX-ray: Hospital-Scale Chest X-ray Database and Benchmarks on Weakly Supervised Classification and Localization of Common Thorax Diseases , 2019, Deep Learning and Convolutional Neural Networks for Medical Imaging and Clinical Informatics.