论文信息 - The CIP sequence rules: Analysis and proposal for a revision

The CIP sequence rules: Analysis and proposal for a revision

Abstract In spite of their value and wide usage the Cahn, Ingold and Prelog (CIP) Sequence Rules have some deficiencies. In particular incompleteness, inconsistency and ambiguity can arise in their application to complex molecules. Therefore, a complete analysis of the CIP Sequence Rules has been made and modified rules are proposed.

[1] D. Seebach,et al. The Unambiguous Specification of the Steric Course of Asymmetric Syntheses , 1982 .

[2] Vladimir Prelog,et al. Specification of Molecular Chirality , 1966 .

[3] Günter Helmchen,et al. Basic Principles of the CIP-System and Proposals for a Revision† , 1982 .

[4] K. Hanson,et al. Prochiral and pseudoasymmetric centers: Implications of recent definitions , 1974 .

[5] Helena Dodziuk,et al. A proposal for a modification of the Cahn, Ingold and Prelog classification of chirality , 1990 .

[6] G. Lyle,et al. The Absolute Configuration of (+)-1-Methyl-2,6-diphenyl-4-piperidone Oxime1 , 1966 .