A comparative study of the genetic components of three subcategories of autism spectrum disorder

[1]  Yi Jiang,et al.  VarCards: an integrated genetic and clinical database for coding variants in the human genome , 2017, Nucleic Acids Res..

[2]  Zhong Sheng Sun,et al.  Targeted sequencing and functional analysis reveal brain-size-related genes and their networks in autism spectrum disorders , 2017, Molecular Psychiatry.

[3]  Zhong Sheng Sun,et al.  Vitamin D‐related genes are subjected to significant de novo mutation burdens in autism spectrum disorder , 2017, American journal of medical genetics. Part B, Neuropsychiatric genetics : the official publication of the International Society of Psychiatric Genetics.

[4]  Bradley P. Coe,et al.  Hotspots of missense mutation identify novel neurodevelopmental disorder genes and functional domains , 2017, Nature Neuroscience.

[5]  R. Anney,et al.  Autism genetics: opportunities and challenges for clinical translation , 2017, Nature Reviews Genetics.

[6]  B. Frey,et al.  Whole genome sequencing resource identifies 18 new candidate genes for autism spectrum disorder , 2017, Nature Neuroscience.

[7]  Bradley P. Coe,et al.  Targeted sequencing identifies 91 neurodevelopmental disorder risk genes with autism and developmental disability biases , 2017, Nature Genetics.

[8]  Zev N. Kronenberg,et al.  De novo genic mutations among a Chinese autism spectrum disorder cohort , 2016, Nature Communications.

[9]  M. Suyama,et al.  CHD8 haploinsufficiency results in autistic-like phenotypes in mice , 2016, Nature.

[10]  Carol Y. B. Liu,et al.  Chd8 mediates cortical neurogenesis via transcriptional regulation of cell cycle and Wnt signaling , 2016, Nature Neuroscience.

[11]  Chandra L. Theesfeld,et al.  Genome-wide prediction and functional characterization of the genetic basis of autism spectrum disorder , 2016, Nature Neuroscience.

[12]  D. Geschwind,et al.  Advancing the understanding of autism disease mechanisms through genetics , 2016, Nature Medicine.

[13]  Bradley P. Coe,et al.  Disruption of POGZ Is Associated with Intellectual Disability and Autism Spectrum Disorders. , 2016, American journal of human genetics.

[14]  Tony Charman,et al.  Diagnosis of autism spectrum disorder: reconciling the syndrome, its diverse origins, and variation in expression , 2016, The Lancet Neurology.

[15]  Chunyu Liu,et al.  Genes with de novo mutations are shared by four neuropsychiatric disorders discovered from NPdenovo database , 2016, Molecular Psychiatry.

[16]  Kali T. Witherspoon,et al.  Disruptive de novo mutations of DYRK1A lead to a syndromic form of autism and ID , 2016, Molecular Psychiatry.

[17]  J Licinio,et al.  Serotonergic neurons derived from induced pluripotent stem cells (iPSCs): a new pathway for research on the biology and pharmacology of major depression , 2016, Molecular Psychiatry.

[18]  Andrew J Sharp,et al.  Back to the past in schizophrenia genomics , 2015, Nature Neuroscience.

[19]  P. Bolton,et al.  Heritability of Autism Spectrum Disorder in a UK Population-Based Twin Sample. , 2015, JAMA psychiatry.

[20]  Stephan J Sanders,et al.  The autism-associated chromatin modifier CHD8 regulates other autism risk genes during human neurodevelopment , 2015, Nature Communications.

[21]  S. Scherer,et al.  Whole-genome sequencing of quartet families with autism spectrum disorder , 2015, Nature Medicine.

[22]  Tao Wang,et al.  mirTrios: an integrated pipeline for detection of de novo and rare inherited mutations from trios-based next-generation sequencing , 2015, Journal of Medical Genetics.

[23]  J. Sebat,et al.  From de novo mutations to personalized therapeutic interventions in autism. , 2015, Annual review of medicine.

[24]  Elhanan Borenstein,et al.  The discovery of integrated gene networks for autism and related disorders , 2015, Genome research.

[25]  Stephan J. Sanders,et al.  Genotype to phenotype relationships in autism spectrum disorders , 2014, Nature Neuroscience.

[26]  Tomas W. Fitzgerald,et al.  Large-scale discovery of novel genetic causes of developmental disorders , 2014, Nature.

[27]  Jinchen Li,et al.  EpilepsyGene: a genetic resource for genes and mutations related to epilepsy , 2014, Nucleic Acids Res..

[28]  Michael Snyder,et al.  Integrated systems analysis reveals a molecular network underlying autism spectrum disorders , 2014, Molecular systems biology.

[29]  Boris Yamrom,et al.  The contribution of de novo coding mutations to autism spectrum disorder , 2014, Nature.

[30]  Christopher S. Poultney,et al.  Synaptic, transcriptional, and chromatin genes disrupted in autism , 2014, Nature.

[31]  Stephan J Sanders,et al.  A framework for the interpretation of de novo mutation in human disease , 2014, Nature Genetics.

[32]  Jay Shendure,et al.  Disruptive CHD8 Mutations Define a Subtype of Autism Early in Development , 2014, Cell.

[33]  Russell S Kirby,et al.  Potential impact of DSM-5 criteria on autism spectrum disorder prevalence estimates. , 2014, JAMA psychiatry.

[34]  Evan E. Eichler,et al.  A Genotype-First Approach to Defining the Subtypes of a Complex Disease , 2014, Cell.

[35]  Kali T. Witherspoon,et al.  A SWI/SNF related autism syndrome caused by de novo mutations in ADNP , 2014, Nature Genetics.

[36]  J. Shendure,et al.  A de novo convergence of autism genetics and molecular neuroscience , 2014, Trends in Neurosciences.

[37]  David R. O'Brien,et al.  Cell Type-Specific Expression Analysis to Identify Putative Cellular Mechanisms for Neurogenetic Disorders , 2014, The Journal of Neuroscience.

[38]  Wei Niu,et al.  Coexpression Networks Implicate Human Midfetal Deep Cortical Projection Neurons in the Pathogenesis of Autism , 2013, Cell.

[39]  S. Horvath,et al.  Integrative Functional Genomic Analyses Implicate Specific Molecular Pathways and Circuits in Autism , 2013, Cell.

[40]  L. Poustka,et al.  Impact of ADHD symptoms on autism spectrum disorder symptom severity. , 2013, Research in developmental disabilities.

[41]  Anirvan Ghosh,et al.  Drug discovery for autism spectrum disorder: challenges and opportunities , 2013, Nature Reviews Drug Discovery.

[42]  E. Ben-David,et al.  Combined analysis of exome sequencing points toward a major role for transcription regulation during brain development in autism , 2013, Molecular Psychiatry.

[43]  E. Boerwinkle,et al.  dbNSFP v2.0: A Database of Human Non‐synonymous SNVs and Their Functional Predictions and Annotations , 2013, Human mutation.

[44]  S. Scherer,et al.  Detection of clinically relevant genetic variants in autism spectrum disorder by whole-genome sequencing. , 2013, American journal of human genetics.

[45]  Kathryn Roeder,et al.  Integrated Model of De Novo and Inherited Genetic Variants Yields Greater Power to Identify Risk Genes , 2013, PLoS genetics.

[46]  D. Robins,et al.  Sensitivity and Specificity of Proposed DSM-5 Criteria for Autism Spectrum Disorder in Toddlers , 2013, Journal of autism and developmental disorders.

[47]  Michael E. Greenberg,et al.  Activity-dependent neuronal signalling and autism spectrum disorder , 2013, Nature.

[48]  Lydia Ng,et al.  Allen Brain Atlas: an integrated spatio-temporal portal for exploring the central nervous system , 2012, Nucleic Acids Res..

[49]  Bradley P. Coe,et al.  Multiplex Targeted Sequencing Identifies Recurrently Mutated Genes in Autism Spectrum Disorders , 2012, Science.

[50]  Lilia M. Iakoucheva,et al.  Whole-Genome Sequencing in Autism Identifies Hot Spots for De Novo Germline Mutation , 2012, Cell.

[51]  J. Veltman,et al.  De novo mutations in human genetic disease , 2012, Nature Reviews Genetics.

[52]  K. Smith,et al.  Brief Report: An Exploratory Study Comparing Diagnostic Outcomes for Autism Spectrum Disorders Under DSM-IV-TR with the Proposed DSM-5 Revision , 2012, Journal of autism and developmental disorders.

[53]  Kenny Q. Ye,et al.  De Novo Gene Disruptions in Children on the Autistic Spectrum , 2012, Neuron.

[54]  Michael F. Walker,et al.  De novo mutations revealed by whole-exome sequencing are strongly associated with autism , 2012, Nature.

[55]  Evan T. Geller,et al.  Patterns and rates of exonic de novo mutations in autism spectrum disorders , 2012, Nature.

[56]  Zachary Warren,et al.  A multisite study of the clinical diagnosis of different autism spectrum disorders. , 2012, Archives of general psychiatry.

[57]  Bradley P. Coe,et al.  Sporadic autism exomes reveal a highly interconnected protein network of de novo mutations , 2012, Nature.

[58]  Charis Eng,et al.  Validation of proposed DSM-5 criteria for autism spectrum disorder. , 2012, Journal of the American Academy of Child and Adolescent Psychiatry.

[59]  J. Kleinman,et al.  Spatiotemporal transcriptome of the human brain , 2011, Nature.

[60]  E. Walker,et al.  Diagnostic and Statistical Manual of Mental Disorders , 2013 .

[61]  Hanna Ebeling,et al.  Autism spectrum disorders according to DSM-IV-TR and comparison with DSM-5 draft criteria: an epidemiological study. , 2011, Journal of the American Academy of Child and Adolescent Psychiatry.

[62]  M. Rieder,et al.  Exome sequencing in sporadic autism spectrum disorders identifies severe de novo mutations , 2011, Nature Genetics.

[63]  M. Daly,et al.  Proteins Encoded in Genomic Regions Associated with Immune-Mediated Disease Physically Interact and Suggest Underlying Biology , 2011, PLoS genetics.

[64]  C. Lord,et al.  The Simons Simplex Collection: A Resource for Identification of Autism Genetic Risk Factors , 2010, Neuron.

[65]  Alexander R. Griffing,et al.  Direct measure of the de novo mutation rate in autism and schizophrenia cohorts. , 2010, American journal of human genetics.

[66]  Gary D Bader,et al.  Functional impact of global rare copy number variation in autism spectrum disorders , 2010, Nature.

[67]  H. Hakonarson,et al.  ANNOVAR: functional annotation of genetic variants from high-throughput sequencing data , 2010, Nucleic acids research.

[68]  M. Ghaziuddin,et al.  Brief Report: Should the DSM V Drop Asperger Syndrome? , 2010, Journal of autism and developmental disorders.

[69]  Robert T. Schultz,et al.  Autism genome-wide copy number variation reveals ubiquitin and neuronal genes , 2009, Nature.

[70]  Steve Horvath,et al.  WGCNA: an R package for weighted correlation network analysis , 2008, BMC Bioinformatics.

[71]  D. Pinto,et al.  Structural variation of chromosomes in autism spectrum disorder. , 2008, American journal of human genetics.

[72]  Kenny Q. Ye,et al.  Strong Association of De Novo Copy Number Mutations with Autism , 2007, Science.

[73]  Thomas Bourgeron,et al.  Mapping autism risk loci using genetic linkage and chromosomal rearrangements , 2007, Nature Genetics.

[74]  C. Dissanayake,et al.  Annotation: The similarities and differences between autistic disorder and Asperger's disorder: a review of the empirical evidence. , 2004, Journal of child psychology and psychiatry, and allied disciplines.

[75]  C. Bell Diagnostic and Statistical Manual of Mental Disorders, Fourth Edition, Text Revision: DSM-IV-TR Quick Reference to the Diagnostic Criteria from DSM-IV-TR , 2001 .

[76]  Dc Washington Diagnostic and Statistical Manual of Mental Disorders, 4th Ed. , 1994 .