Supersaturable self-microemulsifying delivery systems: an approach to enhance oral bioavailability of benzimidazole anticancer drugs

[1]  Y. Chevalier,et al.  Development and structural characterization of a novel nanoemulsion for oral drug delivery , 2020, Colloids and Surfaces A: Physicochemical and Engineering Aspects.

[2]  Min-Soo Kim,et al.  Current Status of Supersaturable Self-Emulsifying Drug Delivery Systems , 2020, Pharmaceutics.

[3]  V. Préat,et al.  Design and evaluation of self-nanoemulsifying drug delivery systems (SNEDDSs) for senicapoc. , 2020, International journal of pharmaceutics.

[4]  S. Safe,et al.  The role of Self Nano Emulsifying drug delivery systems of CDODA-Me in sensitizing Erlotinib resistant Nonsmall cell lung cancer. , 2020, Journal of pharmaceutical sciences.

[5]  Y. Aktaş,et al.  Development and characterization of exendin-4 loaded self-nanoemulsifying system and in vitro evaluation on Caco-2 cell line , 2019, Journal of microencapsulation.

[6]  Christel A. S. Bergström,et al.  Successful oral delivery of poorly water-soluble drugs both depends on the intraluminal behavior of drugs and of appropriate advanced drug delivery systems. , 2019, European journal of pharmaceutical sciences : official journal of the European Federation for Pharmaceutical Sciences.

[7]  Clive G. Wilson,et al.  Impact of regional differences along the gastrointestinal tract of healthy adults on oral drug absorption: An UNGAP review. , 2019, European journal of pharmaceutical sciences : official journal of the European Federation for Pharmaceutical Sciences.

[8]  P. Desai,et al.  Loratadine self-microemulsifying drug delivery systems (SMEDDS) in combination with sulforaphane for the synergistic chemoprevention of pancreatic cancer , 2019, Drug Delivery and Translational Research.

[9]  P. Patel,et al.  Quality by Design Approach for Developing Lipid-Based Nanoformulations of Gliclazide to Improve Oral Bioavailability and Anti-Diabetic Activity , 2019, AAPS PharmSciTech.

[10]  T. Rades,et al.  Exploring the utility of the Chasing Principle: influence of drug-free SNEDDS composition on solubilization of carvedilol, cinnarizine and R3040 in aqueous suspension , 2018, Acta pharmaceutica Sinica. B.

[11]  Gye-Won Lee,et al.  Development and Evaluation of Raloxifene-Hydrochloride-Loaded Supersaturatable SMEDDS Containing an Acidifier , 2018, Pharmaceutics.

[12]  Brian P. Regler,et al.  Drug solubility in fatty acids as a formulation design approach for lipid-based formulations: a technical note , 2018, Drug development and industrial pharmacy.

[13]  H. Fessi,et al.  Lipid-based nanosuspensions for oral delivery of peptides, a critical review. , 2018, International journal of pharmaceutics.

[14]  S. Onoue,et al.  Enhanced pharmacokinetic behavior and hepatoprotective function of ginger extract-loaded supersaturable self-emulsifying drug delivery systems , 2018 .

[15]  Chuan-Yu Wu,et al.  Supersaturable solid self-microemulsifying drug delivery system: precipitation inhibition and bioavailability enhancement , 2017, International journal of nanomedicine.

[16]  P. Graidist,et al.  Enhanced Oral Bioavailability of Curcumin Using a Supersaturatable Self-Microemulsifying System Incorporating a Hydrophilic Polymer; In Vitro and In Vivo Investigations , 2017, AAPS PharmSciTech.

[17]  Y. Choi,et al.  A Polyvinylpyrrolidone-Based Supersaturable Self-Emulsifying Drug Delivery System for Enhanced Dissolution of Cyclosporine A , 2017, Polymers.

[18]  M. Garcia‐Fuentes,et al.  Polyarginine Nanocapsules as a Potential Oral Peptide Delivery Carrier. , 2017, Journal of pharmaceutical sciences.

[19]  Senshang Lin,et al.  Effect of ionization of drug on drug solubilization in SMEDDS prepared using Capmul MCM and caprylic acid , 2016, Asian journal of pharmaceutical sciences.

[20]  V. Préat,et al.  A comparative study of curcumin-loaded lipid-based nanocarriers in the treatment of inflammatory bowel disease. , 2016, Colloids and surfaces. B, Biointerfaces.

[21]  Zhonggui He,et al.  Enhanced oral bioavailability of felodipine by novel solid self-microemulsifying tablets , 2016, Drug development and industrial pharmacy.

[22]  A. Joshi,et al.  Self-microemulsifying drug delivery system (SMEDDS) – challenges and road ahead , 2015, Drug delivery.

[23]  E. Atef,et al.  Using in situ Raman spectroscopy to study the drug precipitation inhibition and supersaturation mechanism of Vitamin E TPGS from self-emulsifying drug delivery systems (SEDDS). , 2015, Journal of pharmaceutical and biomedical analysis.

[24]  A. Bernkop‐Schnürch,et al.  Combining two technologies: multifunctional polymers and self-nanoemulsifying drug delivery system (SNEDDS) for oral insulin administration. , 2013, International Journal of Biological Macromolecules.

[25]  Wei-guo Dai,et al.  Drug precipitation inhibitors in supersaturable formulations. , 2013, International journal of pharmaceutics.

[26]  Wei-xin Ren,et al.  Novel albendazole-chitosan nanoparticles for intestinal absorption enhancement and hepatic targeting improvement in rats. , 2013, Journal of biomedical materials research. Part B, Applied biomaterials.

[27]  V. Stella.  Chemical Drug Stability in Lipids, Modified Lipids, and Polyethylene Oxide-Containing Formulations , 2013, Pharmaceutical Research.

[28]  L. Puskás,et al.  Kinetic analysis of the toxicity of pharmaceutical excipients Cremophor EL and RH40 on endothelial and epithelial cells. , 2013, Journal of pharmaceutical sciences.

[29]  T. Goosen,et al.  Intestinal targeting of drugs: rational design approaches and challenges. , 2013, Current topics in medicinal chemistry.

[30]  B. Abrahamsson,et al.  Oral bioavailability of cinnarizine in dogs: relation to SNEDDS droplet size, drug solubility and in vitro precipitation. , 2013, European journal of pharmaceutical sciences : official journal of the European Federation for Pharmaceutical Sciences.

[31]  K. Kohli,et al.  Study of cosurfactant effect on nanoemulsifying area and development of lercanidipine loaded (SNEDDS) self nanoemulsifying drug delivery system. , 2011, Colloids and surfaces. B, Biointerfaces.

[32]  F. Plakogiannis,et al.  Development and oral bioavailability assessment of a supersaturated self‐microemulsifying drug delivery system (SMEDDS) of albendazole , 2010, The Journal of pharmacy and pharmacology.

[33]  A. Stammati,et al.  The Caco-2 cell line as a model of the intestinal barrier: influence of cell and culture-related factors on Caco-2 cell functional characteristics , 2005, Cell Biology and Toxicology.

[34]  P. Gao,et al.  Development of a supersaturable SEDDS (S-SEDDS) formulation of paclitaxel with improved oral bioavailability. , 2003, Journal of pharmaceutical sciences.

[35]  C. Pouton,et al.  Lipid formulations for oral administration of drugs: non-emulsifying, self-emulsifying and 'self-microemulsifying' drug delivery systems. , 2000, European journal of pharmaceutical sciences : official journal of the European Federation for Pharmaceutical Sciences.

[36]  P. Constantinides,et al.  Formulation and physical characterization of water-in-oil microemulsions containing long- versus medium-chain glycerides , 1997 .

[37]  R. Oberle,et al.  Evaluation of mucosal damage of surfactants in rat jejunum and colon. , 1995, Journal of pharmacological and toxicological methods.

[38]  Eli Ruckenstein,et al.  The origin of thermodynamic stability of microemulsions , 1978 .