A gp130–Src–YAP module links inflammation to epithelial regeneration
暂无分享,去创建一个
John T. Chang | J. Zucman‐Rossi | Y. Maehara | M. Karin | G. Hardiman | A. Yoshimura | K. Guan | E. Raz | K. Taniguchi | W. Sandborn | S. Grivennikov | S. Ho | B. Boland | Li‐Wha Wu | Fa-Xing Yu | Ian Y. Lian | Kepeng Wang | P. R. D. Jong | J. Chang | Li‐Wha Wu | John T. Chang | Li‐Wha Wu
[1] Giuseppe Basso,et al. YAP/TAZ Incorporation in the β-Catenin Destruction Complex Orchestrates the Wnt Response , 2014, Cell.
[2] M. Karin,et al. Liver damage, inflammation, and enhanced tumorigenesis after persistent mTORC1 inhibition. , 2014, Cell metabolism.
[3] Julia B. Cordero,et al. c-Src drives intestinal regeneration and transformation , 2014, The EMBO journal.
[4] A. Elfiky,et al. The role of Src in colon cancer and its therapeutic implications. , 2014, Clinical colorectal cancer.
[5] M. Karin,et al. IL-6 and related cytokines as the critical lynchpins between inflammation and cancer. , 2014, Seminars in immunology.
[6] G. Halder,et al. The two faces of Hippo: targeting the Hippo pathway for regenerative medicine and cancer treatment , 2013, Nature Reviews Drug Discovery.
[7] M F Neurath,et al. New targets for mucosal healing and therapy in inflammatory bowel diseases , 2013, Mucosal Immunology.
[8] S. Baksh,et al. The Tumor Suppressor Gene, RASSF1A, Is Essential for Protection against Inflammation -Induced Injury , 2013, PloS one.
[9] Y. Fujii,et al. YAP and TAZ, Hippo signaling targets, act as a rheostat for nuclear SHP2 function. , 2013, Developmental cell.
[10] W. Freeman,et al. A Degenerative Retinal Process in HIV-Associated Non-Infectious Retinopathy , 2013, PloS one.
[11] H. Clevers,et al. Growing Self-Organizing Mini-Guts from a Single Intestinal Stem Cell: Mechanism and Applications , 2013, Science.
[12] Frank Bergmann,et al. Yes-associated protein up-regulates Jagged-1 and activates the Notch pathway in human hepatocellular carcinoma. , 2013, Gastroenterology.
[13] K. Guan,et al. The Hippo pathway: regulators and regulations. , 2013, Genes & development.
[14] Jill P. Mesirov,et al. β-Catenin-Driven Cancers Require a YAP1 Transcriptional Complex for Survival and Tumorigenesis , 2012, Cell.
[15] Xiang-Dong Fu,et al. Regulation of the Hippo-YAP Pathway by G-Protein-Coupled Receptor Signaling , 2012, Cell.
[16] H. Hermanns,et al. Plasticity and cross-talk of interleukin 6-type cytokines. , 2012, Cytokine & growth factor reviews.
[17] Matthew A. Hibbs,et al. Genome‐Wide Analysis of N1ICD/RBPJ Targets In Vivo Reveals Direct Transcriptional Regulation of Wnt, SHH, and Hippo Pathway Effectors by Notch1 , 2012, Stem cells.
[18] Konstantinos Sousounis,et al. Organ repair and regeneration: an overview. , 2012, Birth defects research. Part C, Embryo today : reviews.
[19] Toshio Tanaka,et al. Therapeutic targeting of the interleukin-6 receptor. , 2012, Annual review of pharmacology and toxicology.
[20] Hans Clevers,et al. Long-term expansion of epithelial organoids from human colon, adenoma, adenocarcinoma, and Barrett's epithelium. , 2011, Gastroenterology.
[21] F. Camargo,et al. Mst1 and Mst2 protein kinases restrain intestinal stem cell proliferation and colonic tumorigenesis by inhibition of Yes-associated protein (Yap) overabundance , 2011, Proceedings of the National Academy of Sciences.
[22] M. Karin,et al. Saturated Fatty Acids Induce c-Src Clustering within Membrane Subdomains, Leading to JNK Activation , 2011, Cell.
[23] M. Karin,et al. Constitutive intestinal NF-κB does not trigger destructive inflammation unless accompanied by MAPK activation , 2011, The Journal of experimental medicine.
[24] Michael Karin,et al. Inflammation meets cancer, with NF-κB as the matchmaker , 2011, Nature Immunology.
[25] J. Zucman‐Rossi,et al. Somatic mutations activating STAT3 in human inflammatory hepatocellular adenomas , 2011, The Journal of experimental medicine.
[26] C. Tamm,et al. Regulation of mouse embryonic stem cell self-renewal by a Yes–YAP–TEAD2 signaling pathway downstream of LIF , 2011, Journal of Cell Science.
[27] Hans Clevers,et al. Paneth cells constitute the niche for Lgr5 stem cells in intestinal crypts , 2011, Nature.
[28] T. Putoczki,et al. More than a sidekick: the IL‐6 family cytokine IL‐11 links inflammation to cancer , 2010, Journal of leukocyte biology.
[29] A. Maitra,et al. The Hippo signaling pathway restricts the oncogenic potential of an intestinal regeneration program. , 2010, Genes & development.
[30] M. Giovannini,et al. The Merlin/NF2 tumor suppressor functions through the YAP oncoprotein to regulate tissue homeostasis in mammals. , 2010, Developmental cell.
[31] T. Kishimoto. IL-6: from its discovery to clinical applications. , 2010, International immunology.
[32] Jongdae Lee,et al. ERK activation drives intestinal tumorigenesis in Apcmin/+ mice , 2010, Nature Medicine.
[33] M. Karin,et al. Immunity, Inflammation, and Cancer , 2010, Cell.
[34] Hua Yu,et al. The JAK2 inhibitor AZD1480 potently blocks Stat3 signaling and oncogenesis in solid tumors. , 2009, Cancer cell.
[35] Jianmin Zhang,et al. YAP-dependent induction of amphiregulin identifies a non-cell-autonomous component of the Hippo pathway , 2009, Nature Cell Biology.
[36] Calvin J Kuo,et al. Sustained in vitro intestinal epithelial culture within a Wnt-dependent stem cell niche , 2009, Nature Medicine.
[37] J. Scheller,et al. Interleukin-6 trans-signaling and colonic cancer associated with inflammatory bowel disease. , 2009, Current pharmaceutical design.
[38] H. Clevers,et al. Single Lgr5 stem cells build cryptvillus structures in vitro without a mesenchymal niche , 2009, Nature.
[39] Janet Rossant,et al. The Hippo signaling pathway components Lats and Yap pattern Tead4 activity to distinguish mouse trophectoderm from inner cell mass. , 2009, Developmental cell.
[40] M. Karin,et al. IL-6 and Stat3 are required for survival of intestinal epithelial cells and development of colitis-associated cancer. , 2009, Cancer cell.
[41] S. Imbeaud,et al. Frequent in-frame somatic deletions activate gp130 in inflammatory hepatocellular tumours , 2009, Nature.
[42] Tetsuya Nakamura,et al. Requirement of Notch activation during regeneration of the intestinal epithelia. , 2009, American journal of physiology. Gastrointestinal and liver physiology.
[43] Li‐Wha Wu,et al. Tie2-R849W mutant in venous malformations chronically activates a functional STAT1 to modulate gene expression. , 2008, The Journal of investigative dermatology.
[44] R. Medzhitov. Origin and physiological roles of inflammation , 2008, Nature.
[45] Y. Shaul,et al. Yap1 phosphorylation by c-Abl is a critical step in selective activation of proapoptotic genes in response to DNA damage. , 2008, Molecular cell.
[46] H. Willenbring,et al. A reproducible and well-tolerated method for 2/3 partial hepatectomy in mice , 2008, Nature Protocols.
[47] R. Jaenisch,et al. YAP1 Increases Organ Size and Expands Undifferentiated Progenitor Cells , 2007, Current Biology.
[48] H. Clevers,et al. Identification of stem cells in small intestine and colon by marker gene Lgr5 , 2007, Nature.
[49] Masato Kubo,et al. SOCS proteins, cytokine signalling and immune regulation , 2007, Nature Reviews Immunology.
[50] S. Bray. Notch signalling: a simple pathway becomes complex , 2006, Nature Reviews Molecular Cell Biology.
[51] Hans Clevers,et al. Notch/γ-secretase inhibition turns proliferative cells in intestinal crypts and adenomas into goblet cells , 2005, Nature.
[52] S. Artavanis-Tsakonas,et al. Notch signals control the fate of immature progenitor cells in the intestine , 2005, Nature.
[53] L. Eckmann,et al. Amendment history : Corrigendum ( April 2005 ) Toll-like receptor 9 – induced type I IFN protects mice from experimental colitis , 2018 .
[54] B. Strooper,et al. Presenilin-dependent γ-secretase activity mediates the intramembranous cleavage of CD44 , 2003, Oncogene.
[55] D. Gumucio,et al. cis Elements of the Villin Gene Control Expression in Restricted Domains of the Vertical (Crypt) and Horizontal (Duodenum, Cecum) Axes of the Intestine* , 2002, The Journal of Biological Chemistry.
[56] S. Hirohashi,et al. Src family kinase inhibitor PP2 restores the E-cadherin/catenin cell adhesion system in human cancer cells and reduces cancer metastasis. , 2002, Clinical cancer research : an official journal of the American Association for Cancer Research.
[57] G. Mills,et al. In vivo and in vitro ovarian carcinoma growth inhibition by a phosphatidylinositol 3-kinase inhibitor (LY294002). , 2000, Clinical cancer research : an official journal of the American Association for Cancer Research.
[58] P. D’Eustachio,et al. Essential role of STAT3 for embryonic stem cell pluripotency. , 1999, Proceedings of the National Academy of Sciences of the United States of America.
[59] S. Akira,et al. Enhanced Th1 activity and development of chronic enterocolitis in mice devoid of Stat3 in macrophages and neutrophils. , 1999, Immunity.
[60] M. Sudol,et al. Yes-associated protein (YAP65) is a proline-rich phosphoprotein that binds to the SH3 domain of the Yes proto-oncogene product. , 1994, Oncogene.