1,2-Diarylimidazoles as inhibitors of cyclooxygenase-2: a quantitative structure-activity relationship study.
暂无分享,去创建一个
[1] L. Goodman,et al. The Pharmacological Basis of Therapeutics , 1941 .
[2] J. Vane,et al. Inhibition of prostaglandin synthesis as a mechanism of action for aspirin-like drugs. , 1971, Nature: New biology.
[3] T. Fujita,et al. Structure-activity study of phenethylamines as substrates of biosynthetic enzymes of sympathetic transmitters. , 1971, Journal of medicinal chemistry.
[4] J. Smith,et al. Aspirin selectively inhibits prostaglandin production in human platelets. , 1971, Nature: New biology.
[5] A. Leo,et al. Substituent constants for correlation analysis in chemistry and biology , 1979 .
[6] D M Clive,et al. Renal syndromes associated with nonsteroidal antiinflammatory drugs. , 1984, The New England journal of medicine.
[7] J. Lombardino. Nonsteroidal antiinflammatory drugs , 1985 .
[8] Y. Pirson,et al. Renal side effects of nonsteroidal antiinflammatory drugs: clinical relevance. , 1986, American journal of kidney diseases : the official journal of the National Kidney Foundation.
[9] R. Erikson,et al. Expression of a mitogen-responsive gene encoding prostaglandin synthase is regulated by mRNA splicing. , 1991, Proceedings of the National Academy of Sciences of the United States of America.
[10] B. Varnum,et al. TIS10, a phorbol ester tumor promoter-inducible mRNA from Swiss 3T3 cells, encodes a novel prostaglandin synthase/cyclooxygenase homologue. , 1991, The Journal of biological chemistry.
[11] C. Torrance,et al. Gastrointestinal damage associated with the use of nonsteroidal antiinflammatory drugs. , 1992, The New England journal of medicine.
[12] T. Hla,et al. Human cyclooxygenase-2 cDNA. , 1992, Proceedings of the National Academy of Sciences of the United States of America.
[13] K. Seibert,et al. Endogenous glucocorticoids regulate an inducible cyclooxygenase enzyme. , 1992, Proceedings of the National Academy of Sciences of the United States of America.
[14] K. Seibert,et al. Selective inhibition of inducible cyclooxygenase 2 in vivo is antiinflammatory and nonulcerogenic. , 1994, Proceedings of the National Academy of Sciences of the United States of America.
[15] C. Koboldt,et al. 1,2-Diarylimidazoles as potent, cyclooxygenase-2 selective, and orally active antiinflammatory agents. , 1997, Journal of medicinal chemistry.
[16] R. Kumar,et al. Novel inhibitors of cyclooxygenase-2: the sulfones and sulfonamides of 1,2-diaryl-4,5-difluorobenzene. Analysis of quantitative structure-activity relationship. , 1998, Journal of enzyme inhibition.