Lymphoid enhancer-binding factor 1, a representative of vertebrate-specific Lef1/Tcf1 sub-family, is a Wnt-beta-catenin pathway target gene in human endothelial cells which regulates matrix metalloproteinase-2 expression and promotes endothelial cell invasion

[1]  Stefan Liebner,et al.  Wnt signaling in the vasculature. , 2013, Experimental cell research.

[2]  T. Holstein,et al.  Subfunctionalization and neofunctionalization of vertebrate Lef/Tcf transcription factors. , 2012, Developmental biology.

[3]  Manisha Sharma,et al.  Regulation of β‐Catenin Nuclear Dynamics by GSK‐3β Involves a LEF‐1 Positive Feedback Loop , 2011, Traffic.

[4]  Costin M. Gherghe,et al.  Wnt1 is a proangiogenic molecule, enhances human endothelial progenitor function, and increases blood flow to ischemic limbs in a HGF‐dependent manner , 2011, FASEB journal : official publication of the Federation of American Societies for Experimental Biology.

[5]  Elisabetta Dejana,et al.  The Role of Wnt Signaling in Physiological and Pathological Angiogenesis , 2010, Circulation research.

[6]  C. Crews,et al.  Activation of the planar cell polarity formin DAAM1 leads to inhibition of endothelial cell proliferation, migration, and angiogenesis , 2010, Proceedings of the National Academy of Sciences.

[7]  T. Schlange,et al.  Wnt3a regulates proliferation and migration of HUVEC via canonical and non-canonical Wnt signaling pathways. , 2009, Biochemical and biophysical research communications.

[8]  B. Olsen,et al.  Snail and Slug promote epithelial-mesenchymal transition through beta-catenin-T-cell factor-4-dependent expression of transforming growth factor-beta3. , 2008, Molecular biology of the cell.

[9]  F. Pépin,et al.  Stromal gene expression predicts clinical outcome in breast cancer , 2008, Nature Medicine.

[10]  J. Kitajewski,et al.  Wnt/Frizzled signaling in angiogenesis , 2008, Angiogenesis.

[11]  R. Holcombe,et al.  Regulation of norrin receptor frizzled-4 by Wnt2 in colon-derived cells , 2007, BMC Cell Biology.

[12]  Beibei Wu,et al.  Wnt signaling induces matrix metalloproteinase expression and regulates T cell transmigration. , 2007, Immunity.

[13]  J. Kitajewski,et al.  Wnt1 and Wnt5a affect endothelial proliferation and capillary length; Wnt2 does not , 2007, Growth factors.

[14]  B. Tycko,et al.  Wnt5a signaling induces proliferation and survival of endothelial cells in vitro and expression of MMP-1 and Tie-2. , 2006, Molecular biology of the cell.

[15]  A. M. Goodwin,et al.  Cultured endothelial cells display endogenous activation of the canonical Wnt signaling pathway and express multiple ligands, receptors, and secreted modulators of Wnt signaling , 2006, Developmental dynamics : an official publication of the American Association of Anatomists.

[16]  M. Ueno,et al.  Wnt5a expression is associated with the tumor proliferation and the stromal vascular endothelial growth factor--an expression in non-small-cell lung cancer. , 2005, Journal of clinical oncology : official journal of the American Society of Clinical Oncology.

[17]  G. Davis,et al.  Biosynthesis, Remodeling, and Functions During Vascular Morphogenesis and Neovessel Stabilization , 2005 .

[18]  R. Holcombe,et al.  Expression of Frzb/secreted Frizzled-related protein 3, a secreted Wnt antagonist, in human androgen-independent prostate cancer PC-3 cells suppresses tumor growth and cellular invasiveness. , 2005, Cancer research.

[19]  R. Holcombe,et al.  Wnt pathway component LEF1 mediates tumor cell invasion and is expressed in human and murine breast cancers lacking ErbB2 (her-2/neu) overexpression. , 2005, International journal of oncology.

[20]  S. Aaronson,et al.  Prostate cancer cells promote osteoblastic bone metastases through Wnts. , 2005, Cancer research.

[21]  Thierry Couffinhal,et al.  FrzA/sFRP-1, a secreted antagonist of the Wnt-Frizzled pathway, controls vascular cell proliferation in vitro and in vivo. , 2004, Cardiovascular research.

[22]  D. Charnock-Jones,et al.  Wnt-1 signaling inhibits human umbilical vein endothelial cell proliferation and alters cell morphology. , 2003, Experimental cell research.

[23]  Hans Clevers,et al.  Caught up in a Wnt storm: Wnt signaling in cancer. , 2003, Biochimica et biophysica acta.

[24]  I. Weissman,et al.  Wnt proteins are lipid-modified and can act as stem cell growth factors , 2003, Nature.

[25]  Karine Hovanes,et al.  A New β-Catenin-dependent Activation Domain in T Cell Factor* 210 , 2003, The Journal of Biological Chemistry.

[26]  M. Buendia,et al.  Transcriptional Activation of Interleukin-8 by β-Catenin-Tcf4* , 2002, The Journal of Biological Chemistry.

[27]  R. Holcombe,et al.  Expression of Wnt ligands and Frizzled receptors in colonic mucosa and in colon carcinoma , 2002, Molecular pathology : MP.

[28]  V. Sukhatme,et al.  Endostatin Causes G1 Arrest of Endothelial Cells through Inhibition of Cyclin D1* , 2002, The Journal of Biological Chemistry.

[29]  D. Gradl,et al.  Functional Diversity of Xenopus Lymphoid Enhancer Factor/T-cell Factor Transcription Factors Relies on Combinations of Activating and Repressing Elements* , 2002, The Journal of Biological Chemistry.

[30]  Karine Hovanes,et al.  β-catenin–sensitive isoforms of lymphoid enhancer factor-1 are selectively expressed in colon cancer , 2001, Nature Genetics.

[31]  J. Papkoff,et al.  Identification of a Wnt-responsive signal transduction pathway in primary endothelial cells. , 1999, Biochemical and biophysical research communications.

[32]  H. Clevers,et al.  Synergy between tumor suppressor APC and the beta-catenin-Tcf4 target Tcf1. , 1999, Science.

[33]  D. Ribatti,et al.  Bone marrow neovascularization, plasma cell angiogenic potential, and matrix metalloproteinase-2 secretion parallel progression of human multiple myeloma. , 1999, Blood.

[34]  C. Edgell,et al.  Permanent cell line expressing human factor VIII-related antigen established by hybridization. , 1983, Proceedings of the National Academy of Sciences of the United States of America.

[35]  E. B. Wilson.  PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES. , 1919, Science.

[36]  R. Holcombe,et al.  Coculture methodologies for the study of Wnt signals. , 2008, Methods in molecular biology.

[37]  A. Albini,et al.  The chemoinvasion assay: a method to assess tumor and endothelial cell invasion and its modulation , 2007, Nature Protocols.

[38]  Jan Kitajewski,et al.  Wnt/beta-catenin signaling induces proliferation, survival and interleukin-8 in human endothelial cells. , 2005, Angiogenesis.

[39]  Jan Kitajewski,et al.  Wnt/β-Catenin Signaling Induces Proliferation, Survival and Interleukin-8 in Human Endothelial Cells , 2005, Angiogenesis.

[40]  M. Waterman,et al.  Lymphoid enhancer factor/T cell factor expression in colorectal cancer , 2004, Cancer and Metastasis Reviews.

[41]  Karine Hovanes,et al.  A new beta-catenin-dependent activation domain in T cell factor. , 2003, The Journal of biological chemistry.

[42]  M. Buendia,et al.  Transcriptional activation of interleukin-8 by beta-catenin-Tcf4. , 2002, The Journal of biological chemistry.