Numerical characterization of DNA sequences in a 2-D graphical representation scheme of low degeneracy

Abstract Some 2-D and 3-D graphical representations of DNA sequences have been given by Gate, Nandy, Leong, Randic, and Guo et al. Based on 2-D graphical representation of DNA sequences, Raychaudhury and Nandy introduced the first-order moments of the x and y coordinates and the radius of the plot of a DNA sequence for indexing scheme and similarity measures of DNA sequences. In this Letter, based on Guo’s novel 2-D graphical representation of DNA sequences of low degeneracy, we introduce the improved first-order moments of the x and y coordinates and the radius of DNA sequences, and the distance of two DNA sequences. The new descriptors of DNA sequences give a good numerical characterization of DNA sequences, which have lower degeneracy.

[1]  Milan Randic,et al.  On the Similarity of DNA Primary Sequences , 2000, J. Chem. Inf. Comput. Sci..

[2]  H. J. Jeffrey Chaos game representation of gene structure. , 1990, Nucleic acids research.

[3]  A. Nandy A new graphical representation and analysis of DNA sequence structure. I: Methodology and application to globin genes , 1994 .

[4]  C. Peng,et al.  Long-range correlations in nucleotide sequences , 1992, Nature.

[5]  Subhash C. Basak,et al.  Simple Numerical Descriptor for Quantifying Effect of Toxic Substances on DNA Sequences , 2000, J. Chem. Inf. Comput. Sci..

[6]  Jin Xu,et al.  Some Notes on 2-D Graphical Representation of DNA Sequence , 2002, J. Chem. Inf. Comput. Sci..

[7]  Jun Wang,et al.  Characteristic Sequences for DNA Primary Sequence , 2002, J. Chem. Inf. Comput. Sci..

[8]  Milan Randić,et al.  On characterization of DNA primary sequences by a condensed matrix , 2000 .

[9]  M. Gates A simple way to look at DNA. , 1986, Journal of theoretical biology.

[10]  Chandan Raychaudhury,et al.  Indexing Scheme and Similarity Measures for Macromolecular Sequences , 1999, J. Chem. Inf. Comput. Sci..

[11]  Milan Randic,et al.  On 3-D Graphical Representation of DNA Primary Sequences and Their Numerical Characterization , 2000, J. Chem. Inf. Comput. Sci..

[12]  Milan Randic,et al.  A novel 2-D graphical representation of DNA sequences of low degeneracy , 2001 .

[13]  M. Randic,et al.  On the Characterization of DNA Primary Sequences by Triplet of Nucleic Acid Bases , 2001, J. Chem. Inf. Comput. Sci..