The influence of environment and origin on brain resident macrophages and implications for therapy
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[1] L. Clarke. Mucopolysaccharidosis Type I , 2016, Definitions.
[2] F. Ginhoux,et al. Fate Mapping via Ms4a3-Expression History Traces Monocyte-Derived Cells , 2019, Cell.
[3] Brian J Cummings,et al. Development of a Chimeric Model to Study and Manipulate Human Microglia In Vivo , 2019, Neuron.
[4] I. Amit,et al. Deletion of a Csf1r enhancer selectively impacts CSF1R expression and development of tissue macrophage populations , 2019, Nature Communications.
[5] F. Ginhoux,et al. Fate Mapping via Ms4a3-Expression History Traces Monocyte-Derived Cells , 2019, Cell.
[6] I. Weissman,et al. Anti-human CD117 antibody-mediated bone marrow niche clearance in nonhuman primates and humanized NSG mice. , 2019, Blood.
[7] Yvan Saeys,et al. A single-cell atlas of mouse brain macrophages reveals unique transcriptional identities shaped by ontogeny and tissue environment , 2019, Nature Neuroscience.
[8] G. Feng,et al. Tmem119-EGFP and Tmem119-CreERT2 Transgenic Mice for Labeling and Manipulating Microglia , 2019, eNeuro.
[9] A. Singleton,et al. Bi-allelic CSF1R Mutations Cause Skeletal Dysplasia of Dysosteosclerosis-Pyle Disease Spectrum and Degenerative Encephalopathy with Brain Malformation. , 2019, American journal of human genetics.
[10] Jeroen A. A. Demmers,et al. Homozygous Mutations in CSF1R Cause a Pediatric-Onset Leukoencephalopathy and Can Result in Congenital Absence of Microglia. , 2019, American journal of human genetics.
[11] E. Huang,et al. Impaired αVβ8 and TGFβ signaling lead to microglial dysmaturation and neuromotor dysfunction , 2019, The Journal of experimental medicine.
[12] J. N. Kay,et al. Microglial Function Is Distinct in Different Anatomical Locations during Retinal Homeostasis and Degeneration , 2019, Immunity.
[13] R. Perlis,et al. Increased synapse elimination by microglia in schizophrenia patient-derived models of synaptic pruning , 2019, Nature Neuroscience.
[14] Tuan Leng Tay,et al. Single-cell profiling identifies myeloid cell subsets with distinct fates during neuroinflammation , 2019, Science.
[15] M. Monje,et al. Methotrexate Chemotherapy Induces Persistent Tri-glial Dysregulation that Underlies Chemotherapy-Related Cognitive Impairment , 2019, Cell.
[16] Evan Z. Macosko,et al. Single‐Cell RNA Sequencing of Microglia throughout the Mouse Lifespan and in the Injured Brain Reveals Complex Cell‐State Changes , 2019, Immunity.
[17] N. Neff,et al. Developmental Heterogeneity of Microglia and Brain Myeloid Cells Revealed by Deep Single-Cell RNA Sequencing , 2018, Neuron.
[18] Tuan Leng Tay,et al. Engrafted parenchymal brain macrophages differ from microglia in transcriptome, chromatin landscape and response to challenge , 2018, Nature Communications.
[19] J. Troy,et al. Long-Term Functional Outcomes after Hematopoietic Stem Cell Transplant for Early Infantile Krabbe Disease. , 2018, Biology of blood and marrow transplantation : journal of the American Society for Blood and Marrow Transplantation.
[20] M. Jagodic,et al. Competitive repopulation of an empty microglial niche yields functionally distinct subsets of microglia-like cells , 2018, Nature Communications.
[21] R. Kahn,et al. Microglia innately develop within cerebral organoids , 2018, Nature Communications.
[22] B. Stevens,et al. Microglia and the Brain: Complementary Partners in Development and Disease. , 2018, Annual review of cell and developmental biology.
[23] J. Pollard,et al. Erythro-myeloid progenitors contribute endothelial cells to blood vessels , 2018, Nature.
[24] J. Pollard,et al. Erythro-myeloid progenitors contribute endothelial cells to blood vessels , 2018, Nature.
[25] S. Hickman,et al. Microglia in neurodegeneration , 2018, Nature Neuroscience.
[26] J. Pocock,et al. Modelling microglial function with induced pluripotent stem cells: an update , 2018, Nature Reviews Neuroscience.
[27] M. Hockin,et al. Two distinct ontogenies confer heterogeneity to mouse brain microglia , 2018, Development.
[28] D. Traver,et al. Embryonic Microglia Derive from Primitive Macrophages and Are Replaced by cmyb-Dependent Definitive Microglia in Zebrafish. , 2018, Cell reports.
[29] Joseph R. Scarpa,et al. Epigenetic regulation of brain region-specific microglia clearance activity , 2018, Nature Neuroscience.
[30] Christopher C. Overall,et al. Peripherally derived macrophages can engraft the brain independent of irradiation and maintain an identity distinct from microglia , 2018, The Journal of experimental medicine.
[31] E. Marcello,et al. Sex-Specific Features of Microglia from Adult Mice , 2018, Cell reports.
[32] F. C. Bennett,et al. A Combination of Ontogeny and CNS Environment Establishes Microglial Identity , 2018, Neuron.
[33] A. Bigas,et al. Blood Development: Hematopoietic Stem Cell Dependence and Independence. , 2018, Cell stem cell.
[34] Z. Mari,et al. Block of A1 astrocyte conversion by microglia is neuroprotective in models of Parkinson’s disease , 2018, Nature Medicine.
[35] M. Jagodic,et al. Fatal demyelinating disease is induced by monocyte-derived macrophages in the absence of TGF-β signaling , 2018, Nature Immunology.
[36] Eyal David,et al. Re-evaluating Microglia Expression Profiles Using RiboTag and Cell Isolation Strategies , 2018, Nature Immunology.
[37] Tuan Leng Tay,et al. Histone Deacetylases 1 and 2 Regulate Microglia Function during Development, Homeostasis, and Neurodegeneration in a Context‐Dependent Manner , 2018, Immunity.
[38] W. Wong,et al. Repopulating retinal microglia restore endogenous organization and function under CX3CL1-CX3CR1 regulation , 2018, Science Advances.
[39] Bo Peng,et al. Repopulated microglia are solely derived from the proliferation of residual microglia after acute depletion , 2018, Nature Neuroscience.
[40] E. Giorgetti,et al. Brain region-specific enhancement of remyelination and prevention of demyelination by the CSF1R kinase inhibitor BLZ945 , 2018, Acta neuropathologica communications.
[41] Melanie A. Huntley,et al. Diverse Brain Myeloid Expression Profiles Reveal Distinct Microglial Activation States and Aspects of Alzheimer's Disease Not Evident in Mouse Models. , 2018, Cell reports.
[42] Z. Wszolek,et al. Diagnostic criteria for adult‐onset leukoencephalopathy with axonal spheroids and pigmented glia due to CSF1R mutation , 2018, European journal of neurology.
[43] B. Barres,et al. Microglia and macrophages in brain homeostasis and disease , 2017, Nature Reviews Immunology.
[44] F. Geissmann,et al. Yolk sac macrophage progenitors traffic to the embryo during defined stages of development , 2018, Nature Communications.
[45] A. Waisman,et al. A novel microglial subset plays a key role in myelinogenesis in developing brain , 2017, The EMBO journal.
[46] M. Rosenblum,et al. A somatic mutation in erythro-myeloid progenitors causes neurodegenerative disease , 2017, Nature.
[47] R. Feil,et al. Microglia turnover with aging and in an Alzheimer's model via long-term in vivo single-cell imaging , 2017, Nature Neuroscience.
[48] Jeff E. Mold,et al. The Lifespan and Turnover of Microglia in the Human Brain , 2017, Cell reports.
[49] Zheng-Xiong Xi,et al. Local Cues Establish and Maintain Region-Specific Phenotypes of Basal Ganglia Microglia , 2017, Neuron.
[50] F. Ginhoux,et al. Induced‐Pluripotent‐Stem‐Cell‐Derived Primitive Macrophages Provide a Platform for Modeling Tissue‐Resident Macrophage Differentiation and Function , 2017, Immunity.
[51] Baptiste N. Jaeger,et al. An environment-dependent transcriptional network specifies human microglia identity , 2017, Science.
[52] I. Amit,et al. A Unique Microglia Type Associated with Restricting Development of Alzheimer’s Disease , 2017, Cell.
[53] A. Andrews,et al. Antibody blockade of CLEC12A delays EAE onset and attenuates disease severity by impairing myeloid cell CNS infiltration and restoring positive immunity , 2017, Scientific Reports.
[54] F. C. Bennett,et al. Diverse Requirements for Microglial Survival, Specification, and Function Revealed by Defined-Medium Cultures , 2017, Neuron.
[55] K. Scearce-Levie,et al. Mice deficient in NRROS show abnormal microglial development and neurological disorders , 2017, Nature Immunology.
[56] Michael D. Cahalan,et al. iPSC-Derived Human Microglia-like Cells to Study Neurological Diseases , 2017, Neuron.
[57] Tuan Leng Tay,et al. A new fate mapping system reveals context-dependent random or clonal expansion of microglia , 2017, Nature Neuroscience.
[58] G. MacGregor,et al. Cell-specific deletion of C1qa identifies microglia as the dominant source of C1q in mouse brain , 2017, Journal of Neuroinflammation.
[59] D. Maric,et al. Differentiation of human and murine induced pluripotent stem cells to microglia-like cells , 2017, Nature Neuroscience.
[60] W. Westbroek,et al. The Complicated Relationship between Gaucher Disease and Parkinsonism: Insights from a Rare Disease , 2017, Neuron.
[61] Manoj Kumar,et al. INGE GRUNDKE-IQBAL AWARD FOR ALZHEIMER’S RESEARCH: NEUROTOXIC REACTIVE ASTROCYTES ARE INDUCED BY ACTIVATED MICROGLIA , 2019, Alzheimer's & Dementia.
[62] O. Garaschuk,et al. Coupled Proliferation and Apoptosis Maintain the Rapid Turnover of Microglia in the Adult Brain , 2017, Cell reports.
[63] B. Becher,et al. Sall1 is a transcriptional regulator defining microglia identity and function , 2016, Nature Immunology.
[64] Christoph Bock,et al. Specification of tissue-resident macrophages during organogenesis , 2016, Science.
[65] Li-Huei Tsai,et al. Efficient derivation of microglia-like cells from human pluripotent stem cells , 2016, Nature Medicine.
[66] I. Amit,et al. Microglia development follows a stepwise program to regulate brain homeostasis , 2016, Science.
[67] Steffen Jung,et al. Microglia contribute to circuit defects in Mecp2 null mice independent of microglia-specific loss of Mecp2 expression , 2016, eLife.
[68] J. Eilers,et al. Neurons exhibit Lyz2 promoter activity in vivo: Implications for using LysM‐Cre mice in myeloid cell research , 2016, European journal of immunology.
[69] M. Wasserstein,et al. Screening of Newborns for Disorders with High Benefit-Risk Ratios Should Be Mandatory , 2016, Journal of Law, Medicine & Ethics.
[70] S. Linnarsson,et al. Origin, fate and dynamics of macrophages at central nervous system interfaces , 2016, Nature Immunology.
[71] Y. Saeys,et al. Yolk Sac Macrophages, Fetal Liver, and Adult Monocytes Can Colonize an Empty Niche and Develop into Functional Tissue-Resident Macrophages. , 2016, Immunity.
[72] F. C. Bennett,et al. New tools for studying microglia in the mouse and human CNS , 2016, Proceedings of the National Academy of Sciences.
[73] E. Chang,et al. Purification and Characterization of Progenitor and Mature Human Astrocytes Reveals Transcriptional and Functional Differences with Mouse , 2016, Neuron.
[74] H. Mefford,et al. Arylsulfatase A Deficiency -- GeneReviews® , 2016 .
[75] K. Stephens,et al. Krabbe Disease -- GeneReviews(®) , 2016 .
[76] H. Mefford,et al. Mucopolysaccharidosis Type I -- GeneReviews(®) , 2016 .
[77] H. Mefford,et al. Gaucher Disease -- GeneReviews(®) , 2016 .
[78] B. Becher,et al. The Cytokine GM-CSF Drives the Inflammatory Signature of CCR2+ Monocytes and Licenses Autoimmunity. , 2015, Immunity.
[79] Jianpeng Sheng,et al. Most Tissue-Resident Macrophages Except Microglia Are Derived from Fetal Hematopoietic Stem Cells. , 2015, Immunity.
[80] Frauke Zipp,et al. Genetic Cell Ablation Reveals Clusters of Local Self-Renewing Microglia in the Mammalian Central Nervous System. , 2015, Immunity.
[81] F. Ginhoux,et al. C-Myb(+) erythro-myeloid progenitor-derived fetal monocytes give rise to adult tissue-resident macrophages. , 2015, Immunity.
[82] M. Scarpa. Mucopolysaccharidosis Type II , 2015 .
[83] T. Autti,et al. Polycystic Lipomembranous Osteodysplasia with Sclerosing Leukoencephalopathy (PLOSL) , 2015 .
[84] D. Holtzman,et al. TREM2 lipid sensing sustains microglia response in an Alzheimer’s disease model , 2015, Cell.
[85] J. Stender,et al. Environment Drives Selection and Function of Enhancers Controlling Tissue-Specific Macrophage Identities , 2015, Cell.
[86] F. Geissmann,et al. Tissue-resident macrophages originate from yolk-sac-derived erythro-myeloid progenitors , 2014, Nature.
[87] I. Amit,et al. Tissue-Resident Macrophage Enhancer Landscapes Are Shaped by the Local Microenvironment , 2014, Cell.
[88] J. Stender,et al. Environment Drives Selection and Function of Enhancers Controlling Tissue-Specific Macrophage Identities , 2014, Cell.
[89] F. Geissmann,et al. Constant replenishment from circulating monocytes maintains the macrophage pool in adult intestine , 2014, Nature Immunology.
[90] Brian L. West,et al. Colony-Stimulating Factor 1 Receptor Signaling Is Necessary for Microglia Viability, Unmasking a Microglia Progenitor Cell in the Adult Brain , 2014, Neuron.
[91] A. Fluharty. Arylsulfatase A Deficiency , 2014 .
[92] S. Gygi,et al. Identification of a Unique TGF-β Dependent Molecular and Functional Signature in Microglia , 2013, Nature Neuroscience.
[93] J. Yates,et al. Microglia Promote Learning-Dependent Synapse Formation through Brain-Derived Neurotrophic Factor , 2013, Cell.
[94] Toshiro K. Ohsumi,et al. The Microglial Sensome Revealed by Direct RNA Sequencing , 2013, Nature Neuroscience.
[95] T. Iwaki,et al. A case of hereditary diffuse leukoencephalopathy with axonal spheroids caused by a de novo mutation in CSF1R masquerading as primary progressive multiple sclerosis , 2013, Multiple sclerosis.
[96] A. Fischer,et al. Outcomes of transplantation using various hematopoietic cell sources in children with Hurler syndrome after myeloablative conditioning. , 2013, Blood.
[97] F. Ginhoux,et al. Tissue-resident macrophages self-maintain locally throughout adult life with minimal contribution from circulating monocytes. , 2013, Immunity.
[98] A. Mildner,et al. Fate mapping reveals origins and dynamics of monocytes and tissue macrophages under homeostasis. , 2013, Immunity.
[99] F. Rosenbauer,et al. Microglia emerge from erythromyeloid precursors via Pu.1- and Irf8-dependent pathways , 2013, Nature Neuroscience.
[100] J. Relton,et al. Colony-stimulating factor 1 receptor (CSF1R) signaling in injured neurons facilitates protection and survival , 2013, The Journal of experimental medicine.
[101] A. Singleton,et al. TREM2 variants in Alzheimer's disease. , 2013, The New England journal of medicine.
[102] A. Hofman,et al. Variant of TREM2 associated with the risk of Alzheimer's disease. , 2013, The New England journal of medicine.
[103] O. Garaschuk,et al. Microglial repopulation model reveals a robust homeostatic process for replacing CNS myeloid cells , 2012, Proceedings of the National Academy of Sciences.
[104] C. Di Serio,et al. Brain conditioning is instrumental for successful microglia reconstitution following hematopoietic stem cell transplantation , 2012, Proceedings of the National Academy of Sciences.
[105] F. Ginhoux,et al. Adult Langerhans cells derive predominantly from embryonic fetal liver monocytes with a minor contribution of yolk sac–derived macrophages , 2012, The Journal of experimental medicine.
[106] J. Pollard,et al. A Lineage of Myeloid Cells Independent of Myb and Hematopoietic Stem Cells , 2012, Science.
[107] T. Martin,et al. Wnt5a-Ror2 signaling between osteoblast-lineage cells and osteoclast precursors enhances osteoclastogenesis , 2012, Nature Medicine.
[108] James C. Cronk,et al. Wild type microglia arrest pathology in a mouse model of Rett syndrome , 2012, Nature.
[109] R. Ransohoff,et al. The Fractalkine Receptor but Not CCR2 Is Present on Microglia from Embryonic Development throughout Adulthood , 2012, The Journal of Immunology.
[110] F. Rossi,et al. Infiltrating monocytes trigger EAE progression, but do not contribute to the resident microglia pool , 2011, Nature Neuroscience.
[111] E. Forsberg,et al. All hematopoietic cells develop from hematopoietic stem cells through Flk2/Flt3-positive progenitor cells. , 2011, Cell stem cell.
[112] Nick C Fox,et al. Common variants in ABCA7, MS4A6A/MS4A4E, EPHA1, CD33 and CD2AP are associated with Alzheimer’s disease , 2011, Nature Genetics.
[113] F. Ginhoux,et al. Fate Mapping Analysis Reveals That Adult Microglia Derive from Primitive Macrophages , 2010, Science.
[114] R. Ransohoff,et al. Selective Chemokine Receptor Usage by Central Nervous System Myeloid Cells in CCR2-Red Fluorescent Protein Knock-In Mice , 2010, PloS one.
[115] H. Zeilhofer,et al. Hoxb8‐Cre mice: A tool for brain‐sparing conditional gene deletion , 2010, Genesis.
[116] L. Liaw,et al. The contribution of the Tie2+ lineage to primitive and definitive hematopoietic cells , 2010, Genesis.
[117] Petr Tvrdik,et al. Hematopoietic Origin of Pathological Grooming in Hoxb8 Mutant Mice , 2010, Cell.
[118] M. Vanier. Niemann-Pick disease type C , 2010, Orphanet journal of rare diseases.
[119] Manfred Schmidt,et al. Hematopoietic Stem Cell Gene Therapy with a Lentiviral Vector in X-Linked Adrenoleukodystrophy , 2009, Science.
[120] A. Mildner,et al. Microglia in the adult brain arise from Ly-6ChiCCR2+ monocytes only under defined host conditions , 2007, Nature Neuroscience.
[121] F. Rossi,et al. Local self-renewal can sustain CNS microglia maintenance and function throughout adult life , 2007, Nature Neuroscience.
[122] H. Moser,et al. Survival analysis of haematopoietic cell transplantation for childhood cerebral X-linked adrenoleukodystrophy: a comparison study , 2007, The Lancet Neurology.
[123] S. Nishikawa,et al. Cell tracing shows the contribution of the yolk sac to adult haematopoiesis , 2007, Nature.
[124] W. Gan,et al. The P2Y12 receptor regulates microglial activation by extracellular nucleotides , 2006, Nature Neuroscience.
[125] L. Naldini,et al. Gene therapy of metachromatic leukodystrophy reverses neurological damage and deficits in mice. , 2006, The Journal of clinical investigation.
[126] Steffen Jung,et al. Control of microglial neurotoxicity by the fractalkine receptor , 2006, Nature Neuroscience.
[127] H. Moser,et al. Cerebral X-linked adrenoleukodystrophy: the international hematopoietic cell transplantation experience from 1982 to 1999. , 2004, Blood.
[128] Gang Tao,et al. A Comparison Study , 2003 .
[129] D. Charnock-Jones,et al. vavCre Transgenic mice: A tool for mutagenesis in hematopoietic and endothelial lineages , 2002, Genesis.
[130] R. Russell,et al. Targeted disruption of the mouse colony-stimulating factor 1 receptor gene results in osteopetrosis, mononuclear phagocyte deficiency, increased primitive progenitor cell frequencies, and reproductive defects. , 2002, Blood.
[131] I. Jambaqué,et al. Long-term effect of bone-marrow transplantation for childhood-onset cerebral X-linked adrenoleukodystrophy , 2000, The Lancet.
[132] B. Pessac,et al. Microglia derive from progenitors, originating from the yolk sac, and which proliferate in the brain. , 1999, Brain research. Developmental brain research.
[133] J. Mandel,et al. Adrénoleucodystrophie liée à l'X , 2007 .
[134] V. Perry,et al. Turnover of resident microglia in the normal adult mouse brain , 1992, Neuroscience.
[135] K. Johnson. An Update. , 1984, Journal of food protection.