TGF-β generates a population of cancer cells residing in G1 phase with high motility and metastatic potential via KRTAP2-3.
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K. Miyazono | Keita Iida | S. Iwabuchi | M. Miura | K. A. Podyma-Inoue | T. Watabe | A. Kaida | D. Koinuma | T. Uchihashi | Kazuki Takahashi | Mariko Okada | Shintaro Sakakitani | S. Hashimoto | Akinari Sugauchi | Susumu Tanaka | Maki Saito | Kyoko Kurioka | Toru Konishi
[1] K. Tomczak,et al. Identification of EMT signaling cross-talk and gene regulatory networks by single-cell RNA sequencing , 2021, Proceedings of the National Academy of Sciences.
[2] Ying Cui,et al. ENC1 Facilitates Colorectal Carcinoma Tumorigenesis and Metastasis via JAK2/STAT5/AKT Axis-Mediated Epithelial Mesenchymal Transition and Stemness , 2021, Frontiers in Cell and Developmental Biology.
[3] Xianghai Wang,et al. Ectodermal-neural cortex 1 affects the biological function of lung cancer through the MAPK pathway , 2021, International journal of molecular medicine.
[4] S. Sant,et al. Interplay between tumor microenvironment and partial EMT as the driver of tumor progression , 2021, iScience.
[5] B. Győrffy,et al. Pancancer survival analysis of cancer hallmark genes , 2020, Scientific Reports.
[6] M. Miura,et al. Visualization of Radiation-Induced Cell Cycle Kinetics with a Fluorescent Ubiquitination-Based Cell Cycle Indicator (Fucci). , 2021, Methods in molecular biology.
[7] Masayuki Yoshida,et al. Age-associated changes in the transcriptomes of non-cultured adipose-derived stem cells from young and old mice assessed via single-cell transcriptome analysis , 2020, PloS one.
[8] S. Zhuang,et al. New Insights Into the Role and Mechanism of Partial Epithelial-Mesenchymal Transition in Kidney Fibrosis , 2020, Frontiers in Physiology.
[9] K. Miyazono,et al. Targeting all transforming growth factor-β isoforms with an Fc chimeric receptor impairs tumor growth and angiogenesis of oral squamous cell cancer , 2020, The Journal of Biological Chemistry.
[10] Bin Wang,et al. Ectodermal‐neural cortex 1 as a novel biomarker predicts poor prognosis and induces metastasis in breast cancer by promoting Wnt/β‐catenin pathway , 2020, Journal of cellular and molecular medicine.
[11] T. Phan,et al. The dormant cancer cell life cycle , 2020, Nature Reviews Cancer.
[12] Peter K. Koo,et al. ZBED2 is an antagonist of interferon regulatory factor 1 and modifies cell identity in pancreatic cancer , 2020, Proceedings of the National Academy of Sciences.
[13] B. Vanderhyden,et al. Context specificity of the EMT transcriptional response , 2020, Nature Communications.
[14] Jeffrey S. Miller,et al. Mesenchymal stromal cells shape the MDS microenvironment by inducing suppressive monocytes that dampen NK cell function. , 2020, JCI insight.
[15] Wenhao Tang,et al. bayNorm: Bayesian gene expression recovery, imputation and normalization for single-cell RNA-sequencing data , 2019, Bioinform..
[16] Steven L Salzberg,et al. Graph-based genome alignment and genotyping with HISAT2 and HISAT-genotype , 2019, Nature Biotechnology.
[17] P. ten Dijke,et al. TGF-β-Mediated Epithelial-Mesenchymal Transition and Cancer Metastasis , 2019, International journal of molecular sciences.
[18] Jun S. Song,et al. Single-Cell Transcriptomics Reveals Spatial and Temporal Turnover of Keratinocyte Differentiation Regulators , 2019, Front. Genet..
[19] K. Shokat,et al. Chronic TGF-β exposure drives stabilized EMT, tumor stemness, and cancer drug resistance with vulnerability to bitopic mTOR inhibition , 2019, Science Signaling.
[20] K. Miyazono,et al. Intracellular and extracellular TGF-β signaling in cancer: some recent topics , 2018, Frontiers of Medicine.
[21] M. Miura,et al. DNA damage response following X-irradiation in oral cancer cell lines HSC3 and HSC4. , 2018, Archives of oral biology.
[22] Paul Hoffman,et al. Integrating single-cell transcriptomic data across different conditions, technologies, and species , 2018, Nature Biotechnology.
[23] B. Treutlein,et al. Reconstructing complex lineage trees from scRNA-seq data using MERLoT , 2018, bioRxiv.
[24] A. Tsirigos,et al. TGF-β-Induced Quiescence Mediates Chemoresistance of Tumor-Propagating Cells in Squamous Cell Carcinoma. , 2017, Cell stem cell.
[25] M. Hattori,et al. Comprehensive single-cell transcriptome analysis reveals heterogeneity in endometrioid adenocarcinoma tissues , 2017, Scientific Reports.
[26] M. Miura,et al. Radiosensitivity of quiescent and proliferating cells grown as multicellular tumor spheroids , 2017, Cancer science.
[27] Xiao-Fan Wang,et al. TGF-β Family Signaling in the Control of Cell Proliferation and Survival. , 2017, Cold Spring Harbor perspectives in biology.
[28] Hye-Min Jeon,et al. MET: roles in epithelial-mesenchymal transition and cancer stemness. , 2017, Annals of translational medicine.
[29] Jeffrey T Leek,et al. Transcript-level expression analysis of RNA-seq experiments with HISAT, StringTie and Ballgown , 2016, Nature Protocols.
[30] A. Moustakas,et al. Transforming growth factor β as regulator of cancer stemness and metastasis , 2016, British Journal of Cancer.
[31] Xiao-Fan Wang,et al. TGF- b Family Signaling in the Control of Cell Proliferation and Survival , 2016 .
[32] Hidemasa Bono,et al. CRISPRdirect: software for designing CRISPR/Cas guide RNA with reduced off-target sites , 2014, Bioinform..
[33] S. O’Brien,et al. Mammalian keratin associated proteins (KRTAPs) subgenomes: disentangling hair diversity and adaptation to terrestrial and aquatic environments , 2014, BMC Genomics.
[34] Sarah A Heerboth,et al. Drug Resistance in Cancer: An Overview , 2014, Cancers.
[35] K. Uzawa,et al. Suppression of metastasis by mirtazapine via restoration of the Lin-7C/β-catenin pathway in human cancer cells , 2014, Scientific Reports.
[36] David A. Scott,et al. Genome engineering using the CRISPR-Cas9 system , 2013, Nature Protocols.
[37] L. Andersson,et al. ZBED Evolution: Repeated Utilization of DNA Transposons as Regulators of Diverse Host Functions , 2013, PloS one.
[38] Masaaki Ito,et al. Characterization of the human hair keratin-associated protein 2 (KRTAP2) gene family. , 2012, The Journal of investigative dermatology.
[39] Kevin W Eliceiri,et al. NIH Image to ImageJ: 25 years of image analysis , 2012, Nature Methods.
[40] Guangchuang Yu,et al. clusterProfiler: an R package for comparing biological themes among gene clusters. , 2012, Omics : a journal of integrative biology.
[41] R. Weinberg,et al. A Perspective on Cancer Cell Metastasis , 2011, Science.
[42] Wenjun Guo,et al. The Epithelial-Mesenchymal Transition Generates Cells with Properties of Stem Cells , 2008, Cell.
[43] Atsushi Miyawaki,et al. Visualizing Spatiotemporal Dynamics of Multicellular Cell-Cycle Progression , 2008, Cell.
[44] Masaaki Ito,et al. Human hair keratin-associated proteins. , 2005, The journal of investigative dermatology. Symposium proceedings.
[45] Pablo Tamayo,et al. Gene set enrichment analysis: A knowledge-based approach for interpreting genome-wide expression profiles , 2005, Proceedings of the National Academy of Sciences of the United States of America.
[46] Brad T. Sherman,et al. DAVID: Database for Annotation, Visualization, and Integrated Discovery , 2003, Genome Biology.
[47] M. Daly,et al. PGC-1α-responsive genes involved in oxidative phosphorylation are coordinately downregulated in human diabetes , 2003, Nature Genetics.
[48] T Tanaka,et al. Up-regulation of the ectodermal-neural cortex 1 (ENC1) gene, a downstream target of the beta-catenin/T-cell factor complex, in colorectal carcinomas. , 2001, Cancer research.
[49] K. Hashimoto. Regulation of keratinocyte function by growth factors. , 2000, Journal of dermatological science.
[50] Y. Nakabeppu,et al. Differential expression of cytokeratin after orthotopic implantation of newly established human tongue cancer cell lines of defined metastatic ability. , 2000, The American journal of pathology.
[51] Fred H. Gage,et al. Development of a Self-Inactivating Lentivirus Vector , 1998, Journal of Virology.
[52] M. Israel,et al. Cloning of human ENC-1 and evaluation of its expression and regulation in nervous system tumors. , 1998, Experimental cell research.
[53] A. Ohuchi,et al. Structure and hair follicle-specific expression of genes encoding the rat high sulfur protein B2 family. , 1998, Gene.
[54] J. Rubenstein,et al. ENC-1: A Novel MammalianKelch-Related Gene Specifically Expressed in the Nervous System Encodes an Actin-Binding Protein , 1997, The Journal of Neuroscience.