Deferoxamine regulates neuroinflammation and iron homeostasis in a mouse model of postoperative cognitive dysfunction

[1]  T. Hökfelt,et al.  Orthopedic surgery modulates neuropeptides and BDNF expression at the spinal and hippocampal levels , 2016, Proceedings of the National Academy of Sciences.

[2]  A. Kraneveld,et al.  Postoperative cognitive dysfunction and neuroinflammation; Cardiac surgery and abdominal surgery are not the same , 2016, Brain, Behavior, and Immunity.

[3]  Hui Tang,et al.  NADPH oxidase 2-derived reactive oxygen species in the hippocampus might contribute to microglial activation in postoperative cognitive dysfunction in aged mice , 2016, Brain, Behavior, and Immunity.

[4]  Jeffrey N. Browndyke,et al.  Postoperative cognitive dysfunction , 2012 .

[5]  Xiaobo Wang,et al.  Bone morphogenic protein-2 regulates the myogenic differentiation of PMVECs in CBDL rat serum-induced pulmonary microvascular remodeling. , 2015, Experimental cell research.

[6]  O. Garaschuk,et al.  Neuroinflammation in Alzheimer's disease , 2015, The Lancet Neurology.

[7]  W. Mi,et al.  Deferoxamine attenuates lipopolysaccharide-induced neuroinflammation and memory impairment in mice , 2015, Journal of Neuroinflammation.

[8]  G. Mashour,et al.  Neurological complications of surgery and anaesthesia. , 2015, British journal of anaesthesia.

[9]  M. Maze,et al.  Stimulation of the α7 Nicotinic Acetylcholine Receptor Protects against Neuroinflammation after Tibia Fracture and Endotoxemia in Mice , 2014, Molecular medicine.

[10]  Jeff H Duyn,et al.  The role of iron in brain ageing and neurodegenerative disorders , 2014, The Lancet Neurology.

[11]  T. Ottens,et al.  Effects of Dexamethasone on Cognitive Decline after Cardiac Surgery: A Randomized Clinical Trial , 2014, Anesthesiology.

[12]  John H. Zhang,et al.  Acute and Delayed Deferoxamine Treatment Attenuates Long-Term Sequelae After Germinal Matrix Hemorrhage in Neonatal Rats , 2014, Stroke.

[13]  M. Baxter,et al.  Systemic Inflammation Impairs Attention and Cognitive Flexibility but Not Associative Learning in Aged Rats: Possible Implications for Delirium , 2014, Front. Aging Neurosci..

[14]  Z. Zuo,et al.  Critical role of inflammatory cytokines in impairing biochemical processes for learning and memory after surgery in rats , 2014, Journal of Neuroinflammation.

[15]  Lauren C Harte-Hargrove,et al.  proBDNF negatively regulates neuronal remodeling, synaptic transmission, and synaptic plasticity in hippocampus. , 2014, Cell reports.

[16]  J. Medina,et al.  BDNF and memory processing , 2014, Neuropharmacology.

[17]  L. Videla,et al.  Acute iron overload and oxidative stress in brain. , 2013, Toxicology.

[18]  W. Ouyang,et al.  Role of Peripheral Inflammatory Markers in Postoperative Cognitive Dysfunction (POCD): A Meta-Analysis , 2013, PloS one.

[19]  M. Lindskog,et al.  Aspirin‐triggered resolvin D1 prevents surgery‐induced cognitive decline , 2013, FASEB journal : official publication of the Federation of American Societies for Experimental Biology.

[20]  E. Marcantonio,et al.  Cerebrospinal Fluid A&bgr; to Tau Ratio and Postoperative Cognitive Change , 2013, Annals of surgery.

[21]  J. Sanchez-Ramos,et al.  Effects of psilocybin on hippocampal neurogenesis and extinction of trace fear conditioning , 2013, Experimental Brain Research.

[22]  M. Maze,et al.  The neuroinflammatory response of postoperative cognitive decline. , 2013, British medical bulletin.

[23]  O. Devinsky,et al.  Neuroinflammation and psychiatric illness , 2013, Journal of Neuroinflammation.

[24]  M. Maze,et al.  Depletion of Bone Marrow–derived Macrophages Perturbs the Innate Immune Response to Surgery and Reduces Postoperative Memory Dysfunction , 2013, Anesthesiology.

[25]  P. Pandharipande,et al.  Association between Endothelial Dysfunction and Acute Brain Dysfunction during Critical Illness , 2013, Anesthesiology.

[26]  Tao Wang,et al.  Intranasal deferoxamine reverses iron-induced memory deficits and inhibits amyloidogenic APP processing in a transgenic mouse model of Alzheimer's disease , 2013, Neurobiology of Aging.

[27]  W. Mi,et al.  Surgical Trauma Induces Iron Accumulation and Oxidative Stress in a Rodent Model of Postoperative Cognitive Dysfunction , 2013, Biological Trace Element Research.

[28]  N. Terrando,et al.  Surgery Upregulates High Mobility Group Box‐1 and Disrupts the Blood–Brain Barrier causing Cognitive Dysfunction in Aged Rats , 2012, CNS neuroscience & therapeutics.

[29]  S. Maier,et al.  Intracisternal Interleukin-1 Receptor Antagonist Prevents Postoperative Cognitive Decline and Neuroinflammatory Response in Aged Rats , 2012, The Journal of Neuroscience.

[30]  N. Andrews,et al.  Divalent metal transporter 1 regulates iron-mediated ROS and pancreatic β cell fate in response to cytokines. , 2012, Cell metabolism.

[31]  P. Kubes,et al.  Immune surveillance in the central nervous system , 2012, Nature Neuroscience.

[32]  M. Maze,et al.  Resolving postoperative neuroinflammation and cognitive decline , 2011, Annals of neurology.

[33]  M. Eckenhoff,et al.  Human Alzheimer and Inflammation Biomarkers after Anesthesia and Surgery , 2011, Anesthesiology.

[34]  M. Weiner,et al.  Perioperative cognitive decline in the aging population. , 2011, Mayo Clinic proceedings.

[35]  M. Maze,et al.  Heat Shock Protein 72 Overexpression Prevents Early Postoperative Memory Decline after Orthopedic Surgery under General Anesthesia in Mice , 2011, Anesthesiology.

[36]  S. Beggs,et al.  Brain-derived neurotrophic factor from microglia: a molecular substrate for neuropathic pain. , 2011, Neuron glia biology.

[37]  L. Della Corte,et al.  Clinically available iron chelators induce neuroprotection in the 6-OHDA model of Parkinson’s disease after peripheral administration , 2011, Journal of Neural Transmission.

[38]  M. Maze,et al.  Tumor necrosis factor-α triggers a cytokine cascade yielding postoperative cognitive decline , 2010, Proceedings of the National Academy of Sciences.

[39]  M. Wessling-Resnick,et al.  Iron homeostasis and the inflammatory response. , 2010, Annual review of nutrition.

[40]  D. Geschwind,et al.  Altered iron metabolism is part of the choroid plexus response to peripheral inflammation. , 2009, Endocrinology.

[41]  L. Rasmussen,et al.  Long-term Consequences of Postoperative Cognitive Dysfunction , 2009, Anesthesiology.

[42]  M. Lynch,et al.  The age‐related attenuation in long‐term potentiation is associated with microglial activation , 2006, Journal of neurochemistry.

[43]  C. Vorhees,et al.  Morris water maze: procedures for assessing spatial and related forms of learning and memory , 2006, Nature Protocols.

[44]  Jing Chen,et al.  Exaggerated neuroinflammation and sickness behavior in aged mice after activation of the peripheral innate immune system , 2005 .

[45]  K. Pantopoulos,et al.  Iron metabolism and toxicity. , 2005, Toxicology and applied pharmacology.

[46]  Elizabeta Nemeth,et al.  IL-6 mediates hypoferremia of inflammation by inducing the synthesis of the iron regulatory hormone hepcidin. , 2004, The Journal of clinical investigation.

[47]  J. Brock,et al.  Proinflammatory cytokines increase iron uptake into human monocytes and synovial fibroblasts from patients with rheumatoid arthritis. , 2004, Medical science monitor : international medical journal of experimental and clinical research.

[48]  Ya Ke,et al.  Iron misregulation in the brain: a primary cause of neurodegenerative disorders , 2003, The Lancet Neurology.

[49]  J. Eaton,et al.  Molecular bases of cellular iron toxicity. , 2002, Free radical biology & medicine.

[50]  M. V. van Eden,et al.  Deleterious iron-mediated oxidation of biomolecules. , 2002, Free radical biology & medicine.

[51]  Bruno Turlin,et al.  A New Mouse Liver-specific Gene, Encoding a Protein Homologous to Human Antimicrobial Peptide Hepcidin, Is Overexpressed during Iron Overload* , 2001, The Journal of Biological Chemistry.

[52]  N. Andrews,et al.  Disorders of iron metabolism. , 1999, The New England journal of medicine.

[53]  M. Lynch,et al.  Evidence That Increased Hippocampal Expression of the Cytokine Interleukin-1β Is a Common Trigger for Age- and Stress-Induced Impairments in Long-Term Potentiation , 1998, The Journal of Neuroscience.

[54]  P. Rabbitt,et al.  Long-term postoperative cognitive dysfunction in the elderly: ISPOCD1 study , 1998, The Lancet.

[55]  J. J. O'Connor,et al.  Interleukin-1β (IL-1β) and tumour necrosis factor (TNF) inhibit long-term potentiation in the rat dentate gyrus in vitro , 1996, Neuroscience Letters.

[56]  D. McLachlan,et al.  Intramuscular desferrioxamine in patients with Alzheimer's disease , 1991, The Lancet.

[57]  P. Ricciardi-Castagnoli,et al.  Monokine production by microglial cell clones , 1989, European journal of immunology.

[58]  Z. Zuo,et al.  Enriched Environment Attenuates Surgery-Induced Impairment of Learning, Memory, and Neurogenesis Possibly by Preserving BDNF Expression , 2014, Molecular Neurobiology.

[59]  A. A. Farooqui,et al.  Iron, neuroinflammation, and Alzheimer's disease. , 2005, Journal of Alzheimer's disease : JAD.

[60]  M. Lynch,et al.  Interleukin-1 beta (IL-1 beta) and tumour necrosis factor (TNF) inhibit long-term potentiation in the rat dentate gyrus in vitro. , 1996, Neuroscience letters.