Generation of free radicals results in increased rates of protein degradation in human erythrocytes.

[1]  K. R. Maples,et al.  In vivo thiyl free radical formation from hemoglobin following administration of hydroperoxides. , 1990, Archives of biochemistry and biophysics.

[2]  R. Novak,et al.  Differential effects of organic hydroperoxides and hydrogen peroxide on proteolysis in human erythrocytes. , 1989, Chemical research in toxicology.

[3]  R. Novak,et al.  Nitrofurantoin-stimulated proteolysis in human erythrocytes: a novel index of toxic insult by nitroaromatics. , 1988, The Journal of pharmacology and experimental therapeutics.

[4]  R. Novak,et al.  Characterization of hydrazine-stimulated proteolysis in human erythrocytes. , 1988, Toxicology and applied pharmacology.

[5]  B. Taffe,et al.  Generation of free radicals from organic hydroperoxide tumor promoters in isolated mouse keratinocytes. Formation of alkyl and alkoxyl radicals from tert-butyl hydroperoxide and cumene hydroperoxide. , 1987, The Journal of biological chemistry.

[6]  A. Goldberg,et al.  Proteins damaged by oxygen radicals are rapidly degraded in extracts of red blood cells. , 1987, The Journal of biological chemistry.

[7]  A. Goldberg,et al.  Oxygen radicals stimulate intracellular proteolysis and lipid peroxidation by independent mechanisms in erythrocytes. , 1987, The Journal of biological chemistry.

[8]  A. De Flora,et al.  Oxidative inactivation of the calcium-stimulated neutral proteinase from human red blood cells by divicine and intracellular protection by reduced glutathione. , 1986, Archives of biochemistry and biophysics.

[9]  J. Chang,et al.  Liquid chromatographic determination of amino acids after gas-phase hydrolysis and derivatization with (dimethylamino)azobenzenesulfonyl chloride. , 1986, Analytical chemistry.

[10]  A. Goldberg,et al.  Red blood cells contain a pathway for the degradation of oxidant-damaged hemoglobin that does not require ATP or ubiquitin. , 1986, The Journal of biological chemistry.

[11]  Paul J Thornalley,et al.  Free radical involvement in the oxidative phenomena induced by tert-butyl hydroperoxide in erythrocytes. , 1983, Biochimica et biophysica acta.

[12]  P. Ortiz de Montellano,et al.  Carbon radicals in the metabolism of alkyl hydrazines. , 1983, The Journal of biological chemistry.

[13]  A. Stern,et al.  Lipid peroxidation and haemoglobin degradation in red blood cells exposed to t-butyl hydroperoxide. The relative roles of haem- and glutathione-dependent decomposition of t-butyl hydroperoxide and membrane lipid hydroperoxides in lipid peroxidation and haemolysis. , 1983, The Biochemical journal.

[14]  R. Novak,et al.  Studies on the mechanism of nitrofurantoin-mediated red cell toxicity. , 1982, The Journal of pharmacology and experimental therapeutics.

[15]  P. Ortiz de Montellano,et al.  N-Phenylprotoporphyrin IX formation in the hemoglobin-phenylhydrazine reaction. Evidence for a protein-stabilized iron-phenyl intermediate. , 1982, The Journal of biological chemistry.

[16]  A. Goldberg,et al.  Oxidized proteins in erythrocytes are rapidly degraded by the adenosine triphosphate-dependent proteolytic system. , 1982, Science.

[17]  H. Itano,et al.  beta-meso-Phenylbiliverdin IX alpha and N-phenylprotoporphyrin IX, products of the reaction of phenylhydrazine with oxyhemoproteins. , 1981, Proceedings of the National Academy of Sciences of the United States of America.

[18]  C. Winterbourn,et al.  Free-Radical Production from Acetylphenylhydrazine and Haemoglobin , 1977 .

[19]  U. K. Laemmli,et al.  Cleavage of Structural Proteins during the Assembly of the Head of Bacteriophage T4 , 1970, Nature.

[20]  Oliver H. Lowry,et al.  Protein measurement with the Folin phenol reagent. , 1951, The Journal of biological chemistry.