论文信息 - Complete reversal of enantioselectivity of an enzyme-catalyzed reaction by directed evolution - 字舞流文

Complete reversal of enantioselectivity of an enzyme-catalyzed reaction by directed evolution

The combination of error prone PCR at high mutation rate and DNA shuffling can be used to invert the direction of enantioselectivity of a lipase-catalyzed hydrolytic kinetic resolution involving a chiral ester.

Manfred T. Reetz | Karl-Erich Jaeger | M. Reetz | K. Jaeger | Stephanie Wilensek | Dongxing Zha | Dongxing Zha | Markus Hermes | Stephanie Wilensek | Markus Hermes

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