Immersive Virtual Environments in Cue Exposure

Cue reactivity to drug-related stimuli is a frequently observed phenomenon in drug addiction. Cue reactivity refers to a classical conditioned response pattern that occurs when an addicted subject is exposed to drug-related stimuli. This response consists of physiological and cognitive reactions. Craving, a subjective desire to use the drug of choice, is believed to play an important role in the occurrence of relapse in the natural setting. Besides craving, other subjective cue-elicited reactions have been reported, including withdrawal symptoms, drug-agonistic effects, and mood swings. Physiological reactions that have been investigated include skin conductance, heart rate, salivation, and body temperature. Conditioned reactivity to cues is an important factor in addiction to alcohol, nicotine, opiates, and cocaine. Cue exposure treatment (CET) refers to a manualized, repeated exposure to drug-related cues, aimed at the reduction of cue reactivity by extinction. In CET, different stimuli are presented, for example, slides, video tapes, pictures, or paraphernalia in nonrealistic, experimental settings. Most often assessments consist in subjective ratings by craving scales. Our pilot study will show that immersive virtual reality (IVR) is as good or even better in eliciting subjective and physiological craving symptoms as classical devices.

[1]  P Hajek,et al.  What do opiate addicts and cigarette smokers mean by "craving"? A pilot study. , 1990, Drug and alcohol dependence.

[2]  F. Müller-Spahn,et al.  Die Behandlung einer Posttraumatischen Belastungsstörung (PTSD) durch In-sensu-Exposition und kognitive Restrukturierung: ein Fallbericht , 1997 .

[3]  A H Bullinger,et al.  From toy to tool: the development of immersive virtual reality environments for psychotherapy of specific phobias. , 1998, Studies in health technology and informatics.

[4]  S. Siegel,et al.  Drug anticipation and drug addiction. The 1998 H. David Archibald Lecture. , 1999, Addiction.

[5]  C. Kouimtsidis,et al.  Role of craving in substance misuse , 2000 .

[6]  Andreas Rößler,et al.  A Rapid Prototyping Framework for the Development of Virtual Environments in Mental Health , 2000, Cyberpsychology Behav. Soc. Netw..

[7]  Andreas Rößler,et al.  Monitoring Human-Virtual Reality Interaction: A Time Series Analysis Approach , 2000, Cyberpsychology Behav. Soc. Netw..

[8]  B. Carter,et al.  Meta-analysis of cue-reactivity in addiction research. , 1999, Addiction.

[9]  P. Pauli,et al.  Modulation of craving by cues having differential overlap with pharmacological effect: evidence for cue approach in smokers and social drinkers , 1999, Psychopharmacology.

[10]  J. Deakin,et al.  Attentional bias for drug cues in opiate dependence , 2000, Psychological Medicine.

[11]  R. Hinson,et al.  Heroin "overdose" death: contribution of drug-associated environmental cues. , 1982, Science.

[12]  M E Hamilton,et al.  Money as a tool to extinguish conditioned responses to cocaine in addicts. , 1998, Journal of clinical psychology.

[13]  Andreas Rößler,et al.  Three-Dimensional Virtual Reality as a Tool in Cognitive-Behavioral Therapy of Claustrophobic Patients , 1998, Cyberpsychology Behav. Soc. Netw..

[14]  Alex H. Bullinger,et al.  3D virtual reality (VR) systems, cognition and creativity , 1998 .

[15]  I. Franken,et al.  Cue reactivity and effects of cue exposure in abstinent posttreatment drug users. , 1999, Journal of substance abuse treatment.

[16]  M. Hertzman,et al.  Clinical guide to alcohol treatment: The Community reinforcement approach , 1996 .

[17]  B. Carter,et al.  Is craving the source of compulsive drug use? , 1998, Journal of psychopharmacology.

[18]  W. Hall,et al.  Levels and correlates of polydrug use among heroin users and regular amphetamine users. , 1995, Drug and alcohol dependence.

[19]  P. Pauli,et al.  Conditioned responses elicited by experimentally produced cues for smoking. , 1998, Canadian journal of physiology and pharmacology.

[20]  A Malizia,et al.  Integrating the cognitive and physiological aspects of craving , 1998, Journal of psychopharmacology.

[21]  Robert J. Meyers,et al.  Clinical Guide to Alcohol Treatment: The Community Reinforcement Approach , 1995 .

[22]  W. van den Brink,et al.  A three-pathway psychobiological model of craving for alcohol. , 1999, Alcohol and alcoholism.

[23]  Louette R. Johnson Lutjens.  Research , 2006 .

[24]  K. Hugdahl,et al.  Selective processing of visual alcohol cues in abstinent alcoholics: an approach-avoidance conflict? , 1997, Addictive behaviors.

[25]  MARCUS F. KUNTZE,et al.  Ethical Codes and Values in a Virtual World , 2002, Cyberpsychology Behav. Soc. Netw..