Genetical genomics of Th1 and Th2 immune response in a baboon model of atherosclerosis risk factors.

[1]  P. Libby,et al.  T-cell activation leads to reduced collagen maturation in atherosclerotic plaques of Apoe(-/-) mice. , 2009, The American journal of pathology.

[2]  C. Ouyang,et al.  Evolutionary Signatures of Common Human Cis-Regulatory Haplotypes , 2008, PloS one.

[3]  L. Almasy,et al.  Discovery of expression QTLs using large-scale transcriptional profiling in human lymphocytes , 2007, Nature Genetics.

[4]  B. Nakken,et al.  Th1/Th2 Imbalance, Measured by Circulating and Intracytoplasmic Inflammatory Cytokines – Immunological Alterations in Acute Coronary Syndrome and Stable Coronary Artery Disease , 2006, Scandinavian journal of immunology.

[5]  J. Rogers,et al.  A second-generation genetic linkage map of the baboon (Papio hamadryas) genome. , 2006, Genomics.

[6]  G. Hansson,et al.  Inflammation and atherosclerosis. , 2006, Annual review of pathology.

[7]  E. Edelman,et al.  Enhanced T-helper-1 lymphocyte activation patterns in acute coronary syndromes. , 2005, Journal of the American College of Cardiology.

[8]  Tatiana Tatusova,et al.  NCBI Reference Sequence (RefSeq): a curated non-redundant sequence database of genomes, transcripts and proteins , 2004, Nucleic Acids Res..

[9]  Tatiana A. Tatusova,et al.  NCBI Reference Sequence (RefSeq): a curated non-redundant sequence database of genomes, transcripts and proteins , 2004, Nucleic Acids Res..

[10]  D. Broide,et al.  IL-5 links adaptive and natural immunity specific for epitopes of oxidized LDL and protects from atherosclerosis. , 2004, The Journal of clinical investigation.

[11]  M. D’Elios,et al.  T helper type 1 lymphocytes drive inflammation in human atherosclerotic lesions , 2003, Proceedings of the National Academy of Sciences of the United States of America.

[12]  Massimo Gadina,et al.  Cytokines and Transcription Factors That Regulate T Helper Cell Differentiation: New Players and New Insights , 2003, Journal of Clinical Immunology.

[13]  J. Piek,et al.  Increased expression of T cell activation markers (CD25, CD26, CD40L and CD69) in atherectomy specimens of patients with unstable angina and acute myocardial infarction. , 2003, Atherosclerosis.

[14]  M. Fishbein,et al.  Overexpression of Interleukin-10 by Activated T Lymphocytes Inhibits Atherosclerosis in LDL Receptor–Deficient Mice by Altering Lymphocyte and Macrophage Phenotypes , 2002, Circulation research.

[15]  R. Leboeuf,et al.  Loss of Lymphotoxin-α but Not Tumor Necrosis Factor-α Reduces Atherosclerosis in Mice* , 2002, The Journal of Biological Chemistry.

[16]  M. Yamaoka-Tojo,et al.  Circulating levels of interleukin 18 reflect etiologies of heart failure: Th1/Th2 cytokine imbalance exaggerates the pathophysiology of advanced heart failure. , 2002, Journal of cardiac failure.

[17]  James L. Young,et al.  Expression of Interleukin (IL)-18 and Functional IL-18 Receptor on Human Vascular Endothelial Cells, Smooth Muscle Cells, and Macrophages , 2002, The Journal of experimental medicine.

[18]  J Blangero,et al.  Large upward bias in estimation of locus-specific effects from genomewide scans. , 2001, American journal of human genetics.

[19]  G. Hansson,et al.  In vivo downregulation of T helper cell 1 immune responses reduces atherogenesis in apolipoprotein E-knockout mice. , 2001, Circulation.

[20]  M. Newell,et al.  T Helper—Cell Phenotype Regulates Atherosclerosis in Mice Under Conditions of Mild Hypercholesterolemia , 2001, Circulation.

[21]  R. Frye,et al.  Perturbation of the T-cell repertoire in patients with unstable angina. , 1999, Circulation.

[22]  U. Andersson,et al.  Cytokine expression in advanced human atherosclerotic plaques: dominance of pro-inflammatory (Th1) and macrophage-stimulating cytokines. , 1999, Atherosclerosis.

[23]  Tzong-Shyuan Lee,et al.  The role of interleukin 12 in the development of atherosclerosis in ApoE-deficient mice. , 1999, Arteriosclerosis, thrombosis, and vascular biology.

[24]  L. Almasy,et al.  Multipoint quantitative-trait linkage analysis in general pedigrees. , 1998, American journal of human genetics.

[25]  S. Heath Markov chain Monte Carlo segregation and linkage analysis for oligogenic models. , 1997, American journal of human genetics.

[26]  L. Demer,et al.  Cross-regulatory roles of interleukin (IL)-12 and IL-10 in atherosclerosis. , 1996, The Journal of clinical investigation.

[27]  R. Seder High-dose IL-2 and IL-15 enhance the in vitro priming of naive CD4+ T cells for IFN-gamma but have differential effects on priming for IL-4. , 1996, Journal of immunology.

[28]  E Feingold,et al.  Gaussian models for genetic linkage analysis using complete high-resolution maps of identity by descent. , 1993, American journal of human genetics.

[29]  G. Hansson,et al.  Detection of activated T lymphocytes in the human atherosclerotic plaque. , 1989, The American journal of pathology.

[30]  O. Kocher,et al.  Localization of T lymphocytes and macrophages in fibrous and complicated human atherosclerotic plaques. , 1988, Atherosclerosis.

[31]  L. Jonasson,et al.  Class II MHC antigen expression in the atherosclerotic plaque: smooth muscle cells express HLA-DR, HLA-DQ and the invariant gamma chain. , 1986, Clinical and experimental immunology.

[32]  G. Bondjers,et al.  Regional Accumulations of T Cells, Macrophages, and Smooth Muscle Cells in the Human Atherosclerotic Plaque , 1986, Arteriosclerosis.

[33]  J. Ott Analysis of Human Genetic Linkage , 1985 .

[34]  N. Mantel The detection of disease clustering and a generalized regression approach. , 1967, Cancer research.

[35]  L. Almasy,et al.  Variance component methods for detecting complex trait loci. , 2001, Advances in genetics.

[36]  B. Spellberg,et al.  Type 1/Type 2 immunity in infectious diseases. , 2001, Clinical infectious diseases : an official publication of the Infectious Diseases Society of America.

[37]  K. Nicholas,et al.  GeneDoc: Analysis and visualization of genetic variation , 1997 .

[38]  Y. Benjamini,et al.  Controlling the false discovery rate: a practical and powerful approach to multiple testing , 1995 .

[39]  A. Becker,et al.  Site of intimal rupture or erosion of thrombosed coronary atherosclerotic plaques is characterized by an inflammatory process irrespective of the dominant plaque morphology. , 1994, Circulation.