Role of gremlin-1 in the pathophysiology of the adipose tissues.

[1]  S. Corvera,et al.  Angiogenesis in adipose tissue and obesity , 2022, Angiogenesis.

[2]  A. Flouris,et al.  The impact of adipokines on vascular networks in adipose tissue. , 2022, Cytokine & growth factor reviews.

[3]  Wei Xue,et al.  Gremlin1 is a therapeutically targetable FGFR1 ligand that regulates lineage plasticity and castration resistance in prostate cancer , 2022, Nature Cancer.

[4]  V. Jiménez,et al.  AAV-mediated BMP7 gene therapy counteracts insulin resistance and obesity , 2022, Molecular therapy. Methods & clinical development.

[5]  F. Berenbaum,et al.  Gremlin-1 and BMP-4 Overexpressed in Osteoarthritis Drive an Osteochondral-Remodeling Program in Osteoblasts and Hypertrophic Chondrocytes , 2022, International journal of molecular sciences.

[6]  I. Talaat,et al.  Insights into the Role of Gremlin-1, a Bone Morphogenic Protein Antagonist, in Cancer Initiation and Progression , 2022, Biomedicines.

[7]  M. Presta,et al.  Production and Biochemical Characterization of Dimeric Recombinant Gremlin-1 , 2022, International journal of molecular sciences.

[8]  G. Colleluori,et al.  From Obesity to Diabetes: The Role of the Adipose Organ. , 2022, Handbook of experimental pharmacology.

[9]  S. Cinti.  The endocrine adipose organ , 2022, Reviews in Endocrine and Metabolic Disorders.

[10]  G. Frühbeck,et al.  Changes in mechanical properties of adipose tissue after bariatric surgery driven by extracellular matrix remodelling and neovascularization are associated with metabolic improvements. , 2022, Acta biomaterialia.

[11]  C. Wolfrum,et al.  Local acetate inhibits brown adipose tissue function , 2021, Proceedings of the National Academy of Sciences.

[12]  L. O’Driscoll,et al.  A method of separating extracellular vesicles from blood shows potential clinical translation, and reveals extracellular vesicle cargo gremlin-1 as a diagnostic biomarker , 2021, Translational oncology.

[13]  Bernard T. Lee,et al.  A single-cell atlas of human and mouse white adipose tissue , 2021, Nature.

[14]  S. O’Reilly.  Gremlin: a complex molecule regulating wound healing and fibrosis , 2021, Cellular and Molecular Life Sciences.

[15]  S. O’Reilly.  Circulating Gremlin-1 is elevated in systemic sclerosis patients , 2021, Journal of scleroderma and related disorders.

[16]  A. Enomoto,et al.  The BMP antagonist gremlin 1 contributes to the development of cortical excitatory neurons, motor balance and fear responses. , 2021, Development.

[17]  J. Distler,et al.  Bone Morphogenetic Protein Antagonist Gremlin-1 Increases Myofibroblast Transition in Dermal Fibroblasts: Implications for Systemic Sclerosis , 2021, Frontiers in Cell and Developmental Biology.

[18]  R. Bourgon,et al.  Gremlin 1+ fibroblastic niche maintains dendritic cell homeostasis in lymphoid tissues , 2021, Nature Immunology.

[19]  N. Inui,et al.  Gremlin-1 for the Differential Diagnosis of Idiopathic Pulmonary Fibrosis Versus Other Interstitial Lung Diseases: A Clinical and Pathophysiological Analysis , 2021, Lung.

[20]  G. Colleluori,et al.  Mammary gland adipocytes in lactation cycle, obesity and breast cancer , 2021, Reviews in Endocrine and Metabolic Disorders.

[21]  O. Borst,et al.  Protective role of Gremlin‐1 in myocardial function , 2021, European journal of clinical investigation.

[22]  F. Villarroya,et al.  The endocrine role of brown adipose tissue: An update on actors and actions , 2021, Reviews in Endocrine and Metabolic Disorders.

[23]  Joanna Kalucka,et al.  Angiogenesis in Adipose Tissue: The Interplay Between Adipose and Endothelial Cells , 2021, Frontiers in Physiology.

[24]  H. Zouhal,et al.  Resistance training, gremlin 1 and macrophage migration inhibitory factor in obese men: a randomised trial , 2020, Archives of physiology and biochemistry.

[25]  Wentao Zhang,et al.  Circ_DHRS3 positively regulates GREM1 expression by competitively targeting miR-183-5p to modulate IL-1β-administered chondrocyte proliferation, apoptosis and ECM degradation. , 2020, International immunopharmacology.

[26]  Y. Surh,et al.  Gremlin-1 Promotes Metastasis of Breast Cancer Cells by Activating STAT3-MMP13 Signaling Pathway , 2020, International journal of molecular sciences.

[27]  Zhenggang Chen,et al.  Diagnostic and therapeutic role of microRNAs in oral cancer , 2020, Oncology reports.

[28]  A. Regev,et al.  snRNA-seq reveals a subpopulation of adipocytes that regulates thermogenesis , 2020, Nature.

[29]  H. Youn,et al.  Gremlin-1 activates Akt/STAT3 signaling, which increases the glycolysis rate in breast cancer cells. , 2020, Biochemical and biophysical research communications.

[30]  R. Abbott,et al.  Adipose Tissue Fibrosis: Mechanisms, Models, and Importance , 2020, International journal of molecular sciences.

[31]  Y. Surh,et al.  Gremlin-1 augments the oestrogen-related receptor α signalling through EGFR activation: implications for the progression of breast cancer , 2020, British Journal of Cancer.

[32]  I. Fong,et al.  Molecular Mechanisms of Adipogenesis: The Anti-adipogenic Role of AMP-Activated Protein Kinase , 2020, Frontiers in Molecular Biosciences.

[33]  Yan-Rong Jiang,et al.  Gremlin in the Vitreous of Patients with Proliferative Diabetic Retinopathy and the Downregulation of Gremlin in Retinal Pigment Epithelial Cells , 2020, Journal of diabetes research.

[34]  M. Duncan,et al.  Fibronectin has multifunctional roles in posterior capsular opacification (PCO). , 2020, Matrix biology : journal of the International Society for Matrix Biology.

[35]  Min Liu,et al.  Gremlin-1 is a key regulator of endothelial-to-mesenchymal transition in human pulmonary artery endothelial cells. , 2020, Experimental cell research.

[36]  S. Farmer,et al.  The Adipocyte Acquires a Fibroblast-Like Transcriptional Signature in Response to a High Fat Diet , 2020, Scientific Reports.

[37]  J. Egido,et al.  VEGFR2 Blockade Improves Renal Damage in an Experimental Model of Type 2 Diabetic Nephropathy , 2020, Journal of clinical medicine.

[38]  Yan-Rong Jiang,et al.  Gremlin mediates the TGF-β-induced induction of profibrogenic genes in human retinal pigment epithelial cells , 2020, Experimental and therapeutic medicine.

[39]  U. Smith,et al.  The Novel Adipokine Gremlin 1 Antagonizes Insulin Action and Is Increased in Type 2 Diabetes and NAFLD/NASH , 2019, Diabetes.

[40]  S. Mitola,et al.  Role of VEGFs in metabolic disorders , 2019, Angiogenesis.

[41]  E. Almaas,et al.  GREM1 is associated with metastasis and predicts poor prognosis in ER-negative breast cancer patients , 2019, Cell Communication and Signaling.

[42]  Xiying Mao,et al.  Gremlin-1: An endogenous BMP antagonist induces epithelial-mesenchymal transition and interferes with redifferentiation in fetal RPE cells with repeated wounds , 2019, Molecular vision.

[43]  D. Brazil,et al.  No evidence of Gremlin1-mediated activation of VEGFR2 signaling in endothelial cells , 2019, The Journal of Biological Chemistry.

[44]  C. Kahn,et al.  Altered adipose tissue and adipocyte function in the pathogenesis of metabolic syndrome. , 2019, The Journal of clinical investigation.

[45]  M. Smid,et al.  Cancer-associated fibroblast-derived Gremlin 1 promotes breast cancer progression , 2019, Breast Cancer Research.

[46]  O. J. Semmes,et al.  Endothelial-to-Mesenchymal Transition in Human Adipose Tissue Vasculature Alters the Particulate Secretome and Induces Endothelial Dysfunction. , 2019, Arteriosclerosis, thrombosis, and vascular biology.

[47]  M. Presta,et al.  VEGFR2 activation mediates the pro-angiogenic activity of BMP4 , 2019, Angiogenesis.

[48]  B. Ma,et al.  Gremlin is a potential target for posterior capsular opacification , 2019, Cell cycle.

[49]  K. Boström,et al.  Beyond the bone: Bone morphogenetic protein signaling in adipose tissue , 2019, Obesity reviews : an official journal of the International Association for the Study of Obesity.

[50]  P. Formisano,et al.  Adipose Tissue Dysfunction as Determinant of Obesity-Associated Metabolic Complications , 2019, International journal of molecular sciences.

[51]  Song Ho Chang,et al.  Excessive mechanical loading promotes osteoarthritis through the gremlin-1–NF-κB pathway , 2019, Nature Communications.

[52]  M. Gladwin,et al.  Nox1/Ref-1-mediated activation of CREB promotes Gremlin1-driven endothelial cell proliferation and migration , 2019, Redox biology.

[53]  B. Aydoğan Mathyk,et al.  Gremlin-1 and gremlin-2 levels in polycystic ovary syndrome and their clinical correlations , 2019, Gynecological endocrinology : the official journal of the International Society of Gynecological Endocrinology.

[54]  Xuechao Feng,et al.  Repression of adipose vascular endothelial growth factor reduces obesity through adipose browning. , 2019, American journal of physiology. Endocrinology and metabolism.

[55]  Yongchao Li,et al.  Knockdown GREM1 suppresses cell growth, angiogenesis, and epithelial‐mesenchymal transition in colon cancer , 2018, Journal of cellular biochemistry.

[56]  A. Ortiz,et al.  Gremlin Regulates Tubular Epithelial to Mesenchymal Transition via VEGFR2: Potential Role in Renal Fibrosis , 2018, Front. Pharmacol..

[57]  B. Yan,et al.  Overexpression of Gremlin 1 by sonic hedgehog signaling promotes pancreatic cancer progression , 2018, International journal of oncology.

[58]  S. Cinti.  Adipose Organ Development and Remodeling. , 2018, Comprehensive Physiology.

[59]  B. Hinz,et al.  Novel differences in gene expression and functional capabilities of myofibroblast populations in idiopathic pulmonary fibrosis. , 2018, American journal of physiology. Lung cellular and molecular physiology.

[60]  A. Ortiz,et al.  Gremlin activates the Notch pathway linked to renal inflammation. , 2018, Clinical science.

[61]  J. Egido,et al.  Gremlin and renal diseases: ready to jump the fence to clinical utility? , 2018, Nephrology, dialysis, transplantation : official publication of the European Dialysis and Transplant Association - European Renal Association.

[62]  R. Zechner,et al.  Brown adipose tissue whitening leads to brown adipocyte death and adipose tissue inflammation[S] , 2018, Journal of Lipid Research.

[63]  Q. Zhai,et al.  An Adipose Tissue Atlas: An Image-Guided Identification of Human-like BAT and Beige Depots in Rodents. , 2018, Cell metabolism.

[64]  Weining Lu,et al.  Identification of direct negative cross-talk between the SLIT2 and bone morphogenetic protein–Gremlin signaling pathways , 2018, The Journal of Biological Chemistry.

[65]  U. Smith,et al.  BMP4 Gene Therapy in Mature Mice Reduces BAT Activation but Protects from Obesity by Browning Subcutaneous Adipose Tissue. , 2017, Cell reports.

[66]  C. Schütte,et al.  Role of bone morphogenetic proteins in sprouting angiogenesis: differential BMP receptor-dependent signaling pathways balance stalk vs. tip cell competence , 2017, FASEB journal : official publication of the Federation of American Societies for Experimental Biology.

[67]  S. Modica,et al.  The dual role of BMP4 in adipogenesis and metabolism , 2017, Adipocyte.

[68]  J. Norman,et al.  The binding of the bone morphogenetic protein antagonist gremlin to kidney heparan sulfate: Such binding is not essential for BMP antagonism. , 2017, The international journal of biochemistry & cell biology.

[69]  Deborah Lavin,et al.  Gremlin1 plays a key role in kidney development and renal fibrosis , 2017, American journal of physiology. Renal physiology.

[70]  Z. Bi,et al.  Gremlin inhibits UV-induced skin cell damages via activating VEGFR2-Nrf2 signaling , 2016, Oncotarget.

[71]  L. Zammataro,et al.  Monomeric gremlin is a novel vascular endothelial growth factor receptor-2 antagonist , 2016, Oncotarget.

[72]  M. Gawaz,et al.  High Plasma Levels of Gremlin‐1 and Macrophage Migration Inhibitory Factor, but Not Their Ratio, Indicate an Increased Risk for Acute Coronary Syndrome in Patients With Type 2 Diabetes Mellitus , 2016, Clinical cardiology.

[73]  M. Hyvönen,et al.  Structure of Gremlin-1 and analysis of its interaction with BMP-2 , 2016, The Biochemical journal.

[74]  S. Cinti,et al.  Convertible visceral fat as a therapeutic target to curb obesity , 2016, Nature Reviews Drug Discovery.

[75]  B. Spiegelman,et al.  A Secreted Slit2 Fragment Regulates Adipose Tissue Thermogenesis and Metabolic Function. , 2016, Cell metabolism.

[76]  A. Fabre,et al.  Altered Expression of Bone Morphogenetic Protein Accessory Proteins in Murine and Human Pulmonary Fibrosis. , 2016, The American journal of pathology.

[77]  M. Presta,et al.  β3 Integrin Promotes Long-Lasting Activation and Polarization of Vascular Endothelial Growth Factor Receptor 2 by Immobilized Ligand , 2015, Arteriosclerosis, thrombosis, and vascular biology.

[78]  B. Mulloy,et al.  Mapping the heparin-binding site of the BMP antagonist gremlin by site-directed mutagenesis based on predictive modelling. , 2015, The Biochemical journal.

[79]  G. Kéri,et al.  Gremlin regulates renal inflammation via the vascular endothelial growth factor receptor 2 pathway , 2015, The Journal of pathology.

[80]  A. Schultze,et al.  Targeting the Gremlin–VEGFR2 axis – a promising strategy for multiple diseases? , 2015, The Journal of pathology.

[81]  G. Greeley,et al.  Gremlin is a key pro-fibrogenic factor in chronic pancreatitis , 2015, Journal of Molecular Medicine.

[82]  J. Egido,et al.  Tubular overexpression of Gremlin in transgenic mice aggravates renal damage in diabetic nephropathy. , 2015, American journal of physiology. Renal physiology.

[83]  M. Jastroch,et al.  Brown adipose tissue: physiological function and evolutionary significance , 2015, Journal of Comparative Physiology B.

[84]  U. Smith,et al.  BMP4 and BMP Antagonists Regulate Human White and Beige Adipogenesis , 2015, Diabetes.

[85]  Limin Liu,et al.  Gremlin promotes peritoneal membrane injury in an experimental mouse model and is associated with increased solute transport in peritoneal dialysis patients. , 2014, The American journal of pathology.

[86]  M. Chatterjee,et al.  Gremlin-1 inhibits macrophage migration inhibitory factor-dependent monocyte function and survival. , 2014, International journal of cardiology.

[87]  D. Guertin,et al.  Adipocytes arise from multiple lineages that are heterogeneously and dynamically distributed , 2014, Nature Communications.

[88]  J. Egido,et al.  Gremlin Activates the Smad Pathway Linked to Epithelial Mesenchymal Transdifferentiation in Cultured Tubular Epithelial Cells , 2014, BioMed research international.

[89]  M. Roden,et al.  BMP4 and BMP7 induce the white-to-brown transition of primary human adipose stem cells. , 2014, American journal of physiology. Cell physiology.

[90]  S. Kajimura,et al.  A new era in brown adipose tissue biology: molecular control of brown fat development and energy homeostasis. , 2014, Annual review of physiology.

[91]  K. Clément,et al.  Endothelial Cells From Visceral Adipose Tissue Disrupt Adipocyte Functions in a Three-Dimensional Setting: Partial Rescue by Angiopoietin-1 , 2014, Diabetes.

[92]  Marco Presta,et al.  Cyclic Adenosine Monophosphate-Response Element–Binding Protein Mediates the Proangiogenic or Proinflammatory Activity of Gremlin , 2014, Arteriosclerosis, thrombosis, and vascular biology.

[93]  M. Gawaz,et al.  Gremlin-1 identifies fibrosis and predicts adverse outcome in patients with heart failure undergoing endomyocardial biopsy. , 2013, Journal of cardiac failure.

[94]  K. Clément,et al.  Fibrosis and adipose tissue dysfunction. , 2013, Cell metabolism.

[95]  J. Graff,et al.  The developmental origins of adipose tissue , 2013, Development.

[96]  J. Bernhagen,et al.  Gremlin-1 Is an Inhibitor of Macrophage Migration Inhibitory Factor and Attenuates Atherosclerotic Plaque Growth in ApoE−/− Mice* , 2013, The Journal of Biological Chemistry.

[97]  P. Scherer,et al.  Obese adipocytes show ultrastructural features of stressed cells and die of pyroptosis , 2013, Journal of Lipid Research.

[98]  S. Kuang,et al.  Distinct populations of adipogenic and myogenic Myf5-lineage progenitors in white adipose tissues[S] , 2013, Journal of Lipid Research.

[99]  C. Bode,et al.  Antagonism and synergy between extracellular BMP modulators Tsg and BMPER balance blood vessel formation , 2013, Journal of Cell Science.

[100]  J. Pollard,et al.  Macrophage biology in development, homeostasis and disease , 2013, Nature.

[101]  A. Ortiz,et al.  Gremlin Is a Downstream Profibrotic Mediator of Transforming Growth Factor-Beta in Cultured Renal Cells , 2013, Nephron Experimental Nephrology.

[102]  Haixia Huang,et al.  Gremlin induces cell proliferation and extra cellular matrix accumulation in mouse mesangial cells exposed to high glucose via the ERK1/2 pathway , 2013, BMC Nephrology.

[103]  D. Guertin,et al.  PTEN loss in the Myf5 lineage redistributes body fat and reveals subsets of white adipocytes that arise from Myf5 precursors. , 2012, Cell metabolism.

[104]  L. Depero,et al.  Role of nanomechanics in canonical and noncanonical pro-angiogenic ligand/VEGF receptor-2 activation. , 2012, Journal of the American Chemical Society.

[105]  Il-Jin Kim,et al.  Gremlin is Overexpressed in Lung Adenocarcinoma and Increases Cell Growth and Proliferation in Normal Lung Cells , 2012, PloS one.

[106]  S. Tafuro,et al.  Adipose Tissue Overexpression of Vascular Endothelial Growth Factor Protects Against Diet-Induced Obesity and Insulin Resistance , 2012, Diabetes.

[107]  C. Mayer,et al.  Using Gene Expression to Predict Differences in the Secretome of Human Omental vs. Subcutaneous Adipose Tissue , 2012, Obesity.

[108]  J. Kim,et al.  Gremlin-1 Induces BMP-Independent Tumor Cell Proliferation, Migration, and Invasion , 2012, PloS one.

[109]  M. Rusnati,et al.  Heparan Sulfate Proteoglycans Mediate the Angiogenic Activity of the Vascular Endothelial Growth Factor Receptor-2 Agonist Gremlin , 2011, Arteriosclerosis, thrombosis, and vascular biology.

[110]  A. Economides,et al.  Loss of Gremlin Delays Primordial Follicle Assembly but Does Not Affect Female Fertility in Mice1 , 2011, Biology of reproduction.

[111]  L. Zammataro,et al.  Gremlin is a novel agonist of the major proangiogenic receptor VEGFR2. , 2010, Blood.

[112]  Jean-Daniel Zucker,et al.  Fibrosis in Human Adipose Tissue: Composition, Distribution, and Link With Lipid Metabolism and Fat Mass Loss , 2010, Diabetes.

[113]  K. Kristiansen,et al.  The emergence of cold-induced brown adipocytes in mouse white fat depots is determined predominantly by white to brown adipocyte transdifferentiation. , 2010, American journal of physiology. Endocrinology and metabolism.

[114]  I. Yoshino,et al.  Promoter hypermethylation of the p16 and Wif-1 genes as an independent prognostic marker in stage IA non-small cell lung cancers. , 2009, International journal of oncology.

[115]  E. Palmer,et al.  Identification and importance of brown adipose tissue in adult humans. , 2009, The New England journal of medicine.

[116]  J. Lang,et al.  Elevated levels of gremlin-1 in eutopic endometrium and peripheral serum in patients with endometriosis. , 2009, Fertility and sterility.

[117]  C. Kahn,et al.  New role of bone morphogenetic protein 7 in brown adipogenesis and energy expenditure , 2008, Nature.

[118]  G. Andrés,et al.  Angiopoietin-1 mediates the proangiogenic activity of the bone morphogenic protein antagonist Drm. , 2008, Blood.

[119]  C. O'brien,et al.  The role of gremlin, a BMP antagonist, and epithelial-to-mesenchymal transition in proliferative vitreoretinopathy. , 2007, Investigative ophthalmology & visual science.

[120]  D. Ribatti,et al.  Bone morphogenic protein antagonist Drm/gremlin is a novel proangiogenic factor. , 2007, Blood.

[121]  Howard Y. Chang,et al.  Bone morphogenetic protein antagonist gremlin 1 is widely expressed by cancer-associated stromal cells and can promote tumor cell proliferation , 2006, Proceedings of the National Academy of Sciences.

[122]  K. Salmenkivi,et al.  Bone morphogenetic protein-4 inhibitor gremlin is overexpressed in idiopathic pulmonary fibrosis. , 2006, The American journal of pathology.

[123]  P. Bosma,et al.  Transcriptional Profiling Reveals Novel Markers of Liver Fibrogenesis , 2006, Journal of Biological Chemistry.

[124]  J. Kim,et al.  The bone morphogenetic protein antagonist gremlin 1 is overexpressed in human cancers and interacts with YWHAH protein , 2006, BMC Cancer.

[125]  C. O'brien,et al.  Gremlin gene expression in bovine retinal pericytes exposed to elevated glucose , 2005, British Journal of Ophthalmology.

[126]  M. Kretzler,et al.  Expression of gremlin, a bone morphogenetic protein antagonist, in human diabetic nephropathy. , 2005, American journal of kidney diseases : the official journal of the National Kidney Foundation.

[127]  D. Brann,et al.  Differential expression of the peripheral benzodiazepine receptor and gremlin during adipogenesis. , 2005, Obesity research.

[128]  Jane Y. Wu,et al.  Cutting Edge: Bone Morphogenetic Protein Antagonists Drm/Gremlin and Dan Interact with Slits and Act as Negative Regulators of Monocyte Chemotaxis12 , 2004, The Journal of Immunology.

[129]  M. Khokha,et al.  Gremlin is the BMP antagonist required for maintenance of Shh and Fgf signals during limb patterning , 2003, Nature Genetics.

[130]  Markus Affolter,et al.  Structural basis of BMP signalling inhibition by the cystine knot protein Noggin , 2002, Nature.

[131]  D. Blair,et al.  Drm/Gremlin transcriptionally activates p21(Cip1) via a novel mechanism and inhibits neoplastic transformation. , 2002, Biochemical and biophysical research communications.

[132]  M. Lu,et al.  The bone morphogenic protein antagonist gremlin regulates proximal‐distal patterning of the lung , 2001, Developmental dynamics : an official publication of the American Association of Anatomists.

[133]  M. Freeman.  Feedback control of intercellular signalling in development , 2000, Nature.

[134]  W. Modi,et al.  DRM/GREMLIN (CKTSF1B1) maps to human chromosome 15 and is highly expressed in adult and fetal brain , 2000, Cytogenetic and Genome Research.

[135]  B. Bardot,et al.  Biosynthesis, Post-translation Modification, and Functional Characterization of Drm/Gremlin* , 2000, The Journal of Biological Chemistry.

[136]  J. Rodríguez-León,et al.  The BMP antagonist Gremlin regulates outgrowth, chondrogenesis and programmed cell death in the developing limb. , 1999, Development.

[137]  R. Harland,et al.  The Xenopus dorsalizing factor Gremlin identifies a novel family of secreted proteins that antagonize BMP activities. , 1998, Molecular cell.

[138]  L. Topol,et al.  Identification of drm, a novel gene whose expression is suppressed in transformed cells and which can inhibit growth of normal but not transformed cells in culture , 1997, Molecular and cellular biology.

[139]  G. Colleluori,et al.  Brown Fat Anatomy in Humans and Rodents. , 2022, Methods in molecular biology.

[140]  Laura Márquez-Expósito,et al.  Molecular Regulation of Notch Signaling by Gremlin. , 2020, Advances in experimental medicine and biology.

[141]  M. Presta,et al.  Involvement of αvβ3 integrin in gremlin-induced angiogenesis , 2012, Angiogenesis.

[142]  Chi-Ying F. Huang,et al.  Expression of gremlin 1 correlates with increased angiogenesis and progression-free survival in patients with pancreatic neuroendocrine tumors , 2012, Journal of Gastroenterology.

[143]  A. Attie,et al.  Hypoxia-Inducible Factor 1α Induces Fibrosis and Insulin Resistance in White Adipose Tissue , 2009, Molecular and Cellular Biology.

[144]  R. Giorgino,et al.  Fat depot-related differences in gene expression, adiponectin secretion, and insulin action and signalling in human adipocytes differentiated in vitro from precursor stromal cells , 2007, Diabetologia.

[145]  O. Avsian-Kretchmer,et al.  Comparative genomic analysis of the eight-membered ring cystine knot-containing bone morphogenetic protein antagonists. , 2004, Molecular endocrinology.