iPSC-Derived Human Microglia-like Cells to Study Neurological Diseases
暂无分享,去创建一个
Michael D. Cahalan | Jack P. Antel | Brian J Cummings | Brian J. Cummings | Cristhian Fimbres | Anshu Agrawal | Vanessa M. Scarfone | M. Carson | Andriy V. Yeromin | M. Cahalan | J. Antel | A. Mortazavi | R. Kayed | R. Ramirez | A. Agrawal | W. Poon | M. Blurton-Jones | B. Cummings | S. Marsh | Rakez Kayed | Edsel M. Abud | E. Martinez | Luke M. Healy | Cecilia H H Nguyen | Sean A Newman | Cristhian Fimbres | C. Caraway | Gianna M. Fote | A. Madany | K. Gylys | Mathew Blurton-Jones | Ricardo N. Ramirez | Wayne W. Poon | Eric S. Martinez | Cecilia H.H. Nguyen | Sean A. Newman | Samuel E. Marsh | Chad A. Caraway | Abdullah M. Madany | Karen H. Gylys | Ali Mortazavi | Monica J. Carson | Edsel Abud | Cecilia H. H. Nguyen
[1] R. Faull,et al. Isolation of highly enriched primary human microglia for functional studies , 2016, Scientific Reports.
[2] Thomas R. Gingeras,et al. STAR: ultrafast universal RNA-seq aligner , 2013, Bioinform..
[3] H. Weiner,et al. Differential roles of microglia and monocytes in the inflamed central nervous system , 2014, The Journal of experimental medicine.
[4] H. Neumann,et al. Sensing the neuronal glycocalyx by glial sialic acid binding immunoglobulin-like lectins , 2014, Neuroscience.
[5] S. Hickman,et al. Microglial Dysfunction and Defective β-Amyloid Clearance Pathways in Aging Alzheimer's Disease Mice , 2008, The Journal of Neuroscience.
[6] J. Grutzendler,et al. CX3CR1 in Microglia Regulates Brain Amyloid Deposition through Selective Protofibrillar Amyloid-β Phagocytosis , 2010, The Journal of Neuroscience.
[7] M. Giustetto,et al. Synaptic Pruning by Microglia Is Necessary for Normal Brain Development , 2011, Science.
[8] P. Rezaie,et al. The origin and cell lineage of microglia—New concepts , 2007, Brain Research Reviews.
[9] I. Amit,et al. Microglia development follows a stepwise program to regulate brain homeostasis , 2016, Science.
[10] R. Nitsch,et al. Astrocyte‐released cytokines induce ramification and outward K+ channel expression in microglia via distinct signalling pathways , 2001, The European journal of neuroscience.
[11] A. Stalder,et al. Invasion of Hematopoietic Cells into the Brain of Amyloid Precursor Protein Transgenic Mice , 2005, The Journal of Neuroscience.
[12] G. Keller,et al. Wnt Signaling Controls the Specification of Definitive and Primitive Hematopoiesis From Human Pluripotent Stem Cells , 2014, Nature Biotechnology.
[13] H. Kettenmann,et al. Physiology of microglia. , 2011, Physiological reviews.
[14] Janna H. Neltner,et al. Disease-related microglia heterogeneity in the hippocampus of Alzheimer’s disease, dementia with Lewy bodies, and hippocampal sclerosis of aging , 2015, Acta Neuropathologica Communications.
[15] D. Maric,et al. Differentiation of human and murine induced pluripotent stem cells to microglia-like cells , 2017, Nature Neuroscience.
[16] N. Perrimon,et al. Functional screening in Drosophila identifies Alzheimer's disease susceptibility genes and implicates Tau-mediated mechanisms. , 2014, Human molecular genetics.
[17] L. Tan,et al. Role of pro-inflammatory cytokines released from microglia in Alzheimer's disease. , 2015, Annals of translational medicine.
[18] Tom Michoel,et al. Microglial brain region-dependent diversity and selective regional sensitivities to ageing , 2015, Nature Neuroscience.
[19] H. Neumann,et al. Alleviation of Neurotoxicity by Microglial Human Siglec-11 , 2010, The Journal of Neuroscience.
[20] W. Gan,et al. The P2Y12 receptor regulates microglial activation by extracellular nucleotides , 2006, Nature Neuroscience.
[21] H. Neumann,et al. Neuronal ‘On’ and ‘Off’ signals control microglia , 2007, Trends in Neurosciences.
[22] F. Ginhoux,et al. Stroma-derived interleukin-34 controls the development and maintenance of langerhans cells and the maintenance of microglia. , 2012, Immunity.
[23] Peter Riederer,et al. Interleukin-1β and interleukin-6 are elevated in the cerebrospinal fluid of Alzheimer's and de novo Parkinson's disease patients , 1995, Neuroscience Letters.
[24] Ben A. Barres,et al. Complement and microglia mediate early synapse loss in Alzheimer mouse models , 2016, Science.
[25] A. Mildner,et al. P2Y12 receptor is expressed on human microglia under physiological conditions throughout development and is sensitive to neuroinflammatory diseases , 2017, Glia.
[26] D. Underhill,et al. C9orf72 is required for proper macrophage and microglial function in mice , 2016, Science.
[27] I. Amit,et al. Host microbiota constantly control maturation and function of microglia in the CNS , 2015, Nature Neuroscience.
[28] M. Prinz,et al. Factors regulating microglia activation , 2013, Front. Cell. Neurosci..
[29] Tatsuya Tsukahara,et al. A Family of non-GPCR Chemosensors Defines an Alternative Logic for Mammalian Olfaction , 2016, Cell.
[30] A. Aguzzi,et al. Microglia: Scapegoat, Saboteur, or Something Else? , 2013, Science.
[31] B. Barres,et al. The complement system: an unexpected role in synaptic pruning during development and disease. , 2012, Annual review of neuroscience.
[32] B. Winblad,et al. Up-regulation of the inflammatory cytokines IFN-γ and IL-12 and down-regulation of IL-4 in cerebral cortex regions of APPSWE transgenic mice , 2002, Journal of Neuroimmunology.
[33] Michelle K. Cahill,et al. Progranulin Deficiency Promotes Circuit-Specific Synaptic Pruning by Microglia via Complement Activation , 2016, Cell.
[34] Keith A. Johnson,et al. CD33 Alzheimer’s disease locus: Altered monocyte function and amyloid biology , 2013, Nature Neuroscience.
[35] G. Keller,et al. Development of the hemangioblast defines the onset of hematopoiesis in human ES cell differentiation cultures. , 2007, Blood.
[36] Colin N. Dewey,et al. RSEM: accurate transcript quantification from RNA-Seq data with or without a reference genome , 2011, BMC Bioinformatics.
[37] P Riederer,et al. Interleukin-1 beta and interleukin-6 are elevated in the cerebrospinal fluid of Alzheimer's and de novo Parkinson's disease patients. , 1995, Neuroscience letters.
[38] S. Gygi,et al. Identification of a Unique TGF-β Dependent Molecular and Functional Signature in Microglia , 2013, Nature Neuroscience.
[39] F. C. Bennett,et al. New tools for studying microglia in the mouse and human CNS , 2016, Proceedings of the National Academy of Sciences.
[40] G. Paxinos,et al. ABCA7 Mediates Phagocytic Clearance of Amyloid-β in the Brain. , 2016, Journal of Alzheimer's disease : JAD.
[41] B. Miller,et al. Rare TREM2 variants associated with Alzheimer’s disease display reduced cell surface expression , 2016, Acta Neuropathologica Communications.
[42] M. Diamond,et al. IL-34 is a tissue-restricted ligand of CSF1R required for the development of Langerhans cells and microglia , 2012, Nature Immunology.
[43] A. Palucka,et al. Development and function of human innate immune cells in a humanized mouse model , 2014, Nature Biotechnology.
[44] Alison M. Goate,et al. Alzheimer’s Disease Risk Polymorphisms Regulate Gene Expression in the ZCWPW1 and the CELF1 Loci , 2016, PloS one.
[45] J. Antel,et al. Isolating, culturing, and polarizing primary human adult and fetal microglia. , 2013, Methods in molecular biology.
[46] I. Amit,et al. Tissue-Resident Macrophage Enhancer Landscapes Are Shaped by the Local Microenvironment , 2014, Cell.
[47] V. Mathura,et al. Inflammatory cytokine levels correlate with amyloid load in transgenic mouse models of Alzheimer's disease , 2005, Journal of Neuroinflammation.
[48] T. Möller,et al. Central nervous system myeloid cells as drug targets: current status and translational challenges , 2015, Nature Reviews Drug Discovery.
[49] Madeline A. Lancaster,et al. Cerebral organoids model human brain development and microcephaly , 2013, Nature.
[50] J. Hardy,et al. Microglial genes regulating neuroinflammation in the progression of Alzheimer's disease , 2016, Current Opinion in Neurobiology.
[51] B. Stevens,et al. New insights on the role of microglia in synaptic pruning in health and disease , 2016, Current Opinion in Neurobiology.
[52] U. Sengupta,et al. Identification of oligomers at early stages of tau aggregation in Alzheimer's disease , 2012, FASEB journal : official publication of the Federation of American Societies for Experimental Biology.
[53] K. Lunetta,et al. Association of TREM2 variants with Alzheimer's disease in African-Americans: For the Alzheimer's Disease Genetics Consortium (ADGC) , 2013, Alzheimer's & Dementia.
[54] T. Maniatis,et al. An RNA-Sequencing Transcriptome and Splicing Database of Glia, Neurons, and Vascular Cells of the Cerebral Cortex , 2014, The Journal of Neuroscience.
[55] J. Pollard,et al. A Lineage of Myeloid Cells Independent of Myb and Hematopoietic Stem Cells , 2012, Science.
[56] J. Koenigsknecht-Talboo,et al. Microglial Phagocytosis Induced by Fibrillar β-Amyloid and IgGs Are Differentially Regulated by Proinflammatory Cytokines , 2005, The Journal of Neuroscience.
[57] Jennifer Luebke,et al. Depletion of microglia and inhibition of exosome synthesis halt tau propagation , 2015, Nature Neuroscience.
[58] Lino C. Gonzalez,et al. TREM2 Binds to Apolipoproteins, Including APOE and CLU/APOJ, and Thereby Facilitates Uptake of Amyloid-Beta by Microglia , 2016, Neuron.
[59] F. Müller,et al. Neural stem cells improve cognition via BDNF in a transgenic model of Alzheimer disease , 2009, Proceedings of the National Academy of Sciences.
[60] D. Liebermann,et al. Interferon regulatory factor 1 is a myeloid differentiation primary response gene induced by interleukin 6 and leukemia inhibitory factor: role in growth inhibition. , 1991, Cell growth & differentiation : the molecular biology journal of the American Association for Cancer Research.
[61] Steffen Jung,et al. TGF‐β signaling through SMAD2/3 induces the quiescent microglial phenotype within the CNS environment , 2012, Glia.
[62] R. Ransohoff,et al. Heterogeneity of CNS myeloid cells and their roles in neurodegeneration , 2011, Nature Neuroscience.
[63] Li-Huei Tsai,et al. Efficient derivation of microglia-like cells from human pluripotent stem cells , 2016, Nature Medicine.
[64] C. Glass,et al. Molecular control of activation and priming in macrophages , 2015, Nature Immunology.
[65] F. Gage,et al. Mutant Huntingtin Promotes Autonomous Microglia Activation via Myeloid Lineage-determining Factors Fold Difference from the Mean , 2022 .
[66] Andrew D. Rouillard,et al. Enrichr: a comprehensive gene set enrichment analysis web server 2016 update , 2016, Nucleic Acids Res..
[67] F. Geissmann,et al. The transcription factor NR4A1 (Nur77) controls bone marrow differentiation and the survival of Ly6C− monocytes , 2011, Nature Immunology.
[68] C. Cotman,et al. Apoptosis is induced by beta-amyloid in cultured central nervous system neurons. , 1993, Proceedings of the National Academy of Sciences of the United States of America.
[69] Mark D. Robinson,et al. edgeR: a Bioconductor package for differential expression analysis of digital gene expression data , 2009, Bioinform..
[70] Toshiro K. Ohsumi,et al. The Microglial Sensome Revealed by Direct RNA Sequencing , 2013, Nature Neuroscience.
[71] A. Lakatos,et al. The adaptive immune system restrains Alzheimer’s disease pathogenesis by modulating microglial function , 2016, Proceedings of the National Academy of Sciences.
[72] K. Gylys,et al. Quantitative characterization of crude synaptosomal fraction (P‐2) components by flow cytometry , 2000, Journal of neuroscience research.
[73] Marco Prinz,et al. Microglia and brain macrophages in the molecular age: from origin to neuropsychiatric disease , 2014, Nature Reviews Neuroscience.
[74] Stephen J. Smith,et al. Astrocytes mediate synapse elimination through MEGF10 and MERTK pathways , 2013, Nature.
[75] F. Ginhoux,et al. Targeting innate immunity for neurodegenerative disorders of the central nervous system , 2016, Journal of neurochemistry.
[76] F. Ginhoux,et al. Fate Mapping Analysis Reveals That Adult Microglia Derive from Primitive Macrophages , 2010, Science.
[77] B. Finsen,et al. Accelerated microglial pathology is associated with Aβ plaques in mouse models of Alzheimer’s disease , 2014, Aging cell.
[78] F. Rosenbauer,et al. Microglia emerge from erythromyeloid precursors via Pu.1- and Irf8-dependent pathways , 2013, Nature Neuroscience.
[79] P. Séguéla,et al. P2Y12 expression and function in alternatively activated human microglia , 2015, Neurology: Neuroimmunology & Neuroinflammation.
[80] P. Rezaie,et al. Colonisation of the developing human brain and spinal cord by microglia: a review , 1999, Microscopy research and technique.
[81] Avi Ma'ayan,et al. Enrichr: interactive and collaborative HTML5 gene list enrichment analysis tool , 2013, BMC Bioinformatics.
[82] M. Guillot-Sestier,et al. Innate immunity in Alzheimer's disease: a complex affair. , 2013, CNS & neurological disorders drug targets.
[83] M. A. Ajmone-Cat,et al. TGF‐β and LPS modulate ADP‐induced migration of microglial cells through P2Y1 and P2Y12 receptor expression , 2010, Journal of neurochemistry.