ChemInform Abstract: Synthesis of 2-Substituted-2,3-dihydro-5-benzoyl-1H-1,3,2-benzodiazaphosphole 2-Oxides/Sulfides.

Syntheses of 2-aryloxy/2-chloro ethoxy-2,3-dihydro-5-benzoyl-1H-1,3,2-benzodiaza-phosphole 2-oxides 3a–h were accomplished by reactions of equimolar quantities of 3,4-diaminobenzophenone (1) with various aryl/chloroethoxy phosphorodichloridates 2a–g and 2h in the presence of triethylamine at 50–60°C. Compounds 3i–k were prepared by reacting 3,4-diaminobenzophenone (1) with aryl thiophosphorodichloridates 2i–k under similar conditions. They were characterized by IR, 1H, 13C, and 31P NMR spectral data. Some of these products possessed siginificant antimicrobial activity © 2002 Wiley Periodicals, Inc. Heteroatom Chem 13:340–345, 2002; Published online in Wiley Interscience (www.interscience.wiley.com). DOI 10.1002/hc.10044

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