Structural and dynamical characteristics of tropomyosin epitopes as the major allergens in shrimp.

[1]  Joseph L. Baumert,et al.  Conformational stability of digestion-resistant peptides of peanut conglutins reveals the molecular basis of their allergenicity , 2016, Scientific Reports.

[2]  Wenjun Zheng,et al.  Investigating the effects of tropomyosin mutations on its flexibility and interactions with filamentous actin using molecular dynamics simulation , 2016, Journal of Muscle Research and Cell Motility.

[3]  Julian E. Fuchs,et al.  Localization of Millisecond Dynamics: Dihedral Entropy from Accelerated MD , 2016, Journal of chemical theory and computation.

[4]  Stefan Raunser,et al.  Cryo-EM structure of a human cytoplasmic actomyosin complex at near-atomic resolution , 2016, Nature.

[5]  Stefan Fischer,et al.  Phosphorylation of Ser283 enhances the stiffness of the tropomyosin head-to-tail overlap domain. , 2015, Archives of biochemistry and biophysics.

[6]  Julian E. Fuchs,et al.  The Impact of Nitration on the Structure and Immunogenicity of the Major Birch Pollen Allergen Bet v 1.0101 , 2014, PloS one.

[7]  Marek Orzechowski,et al.  An atomic model of the tropomyosin cable on F-actin. , 2014, Biophysical journal.

[8]  Marek Orzechowski,et al.  The structural dynamics of α-tropomyosin on F-actin shape the overlap complex between adjacent tropomyosin molecules. , 2014, Archives of biochemistry and biophysics.

[9]  Marek Orzechowski,et al.  Structure and flexibility of the tropomyosin overlap junction. , 2014, Biochemical and biophysical research communications.

[10]  Jason M. Swails,et al.  Constant pH Replica Exchange Molecular Dynamics in Explicit Solvent Using Discrete Protonation States: Implementation, Testing, and Validation , 2014, Journal of chemical theory and computation.

[11]  S. Stagg,et al.  Cryo-EM structures of the actin:tropomyosin filament reveal the mechanism for the transition from C- to M-state. , 2013, Journal of molecular biology.

[12]  Wenjun Zheng,et al.  Probing the flexibility of tropomyosin and its binding to filamentous actin using molecular dynamics simulations. , 2013, Biophysical journal.

[13]  Ross C. Walker,et al.  An overview of the Amber biomolecular simulation package , 2013 .

[14]  A. Holck,et al.  Tropomyosin from tilapia (Oreochromis mossambicus) as an allergen , 2013, Clinical and experimental allergy : journal of the British Society for Allergy and Clinical Immunology.

[15]  Stefan Fischer,et al.  The flexibility of two tropomyosin mutants, D175N and E180G, that cause hypertrophic cardiomyopathy. , 2012, Biochemical and biophysical research communications.

[16]  Stefan Raunser,et al.  Structure of the Rigor Actin-Tropomyosin-Myosin Complex , 2012, Cell.

[17]  S. Watabe,et al.  Thermodynamic characterization of muscle tropomyosins from marine invertebrates. , 2011, Comparative biochemistry and physiology. Part B, Biochemistry & molecular biology.

[18]  M. Yokoro,et al.  Gastrointestinal Digestion and Absorption of Pen j 1, a Major Allergen from Kuruma Prawn, Penaeus japonicus , 2011, Bioscience, biotechnology, and biochemistry.

[19]  Stefan Fischer,et al.  The relationship between curvature, flexibility and persistence length in the tropomyosin coiled-coil. , 2010, Journal of structural biology.

[20]  Stefan Fischer,et al.  Curvature variation along the tropomyosin molecule. , 2010, Journal of structural biology.

[21]  Stefan Fischer,et al.  The shape and flexibility of tropomyosin coiled coils: implications for actin filament assembly and regulation. , 2010, Journal of molecular biology.

[22]  S. K. Lakkaraju,et al.  Modulation of Elasticity in Functionally Distinct Domains of the Tropomyosin Coiled-Coil , 2009, Cellular and molecular bioengineering.

[23]  N. Oda,et al.  Two-crystal structures of tropomyosin C-terminal fragment 176-273: exposure of the hydrophobic core to the solvent destabilizes the tropomyosin molecule. , 2008, Biophysical journal.

[24]  Y. Shirakihara,et al.  Structural basis for tropomyosin overlap in thin (actin) filaments and the generation of a molecular swivel by troponin-T , 2008, Proceedings of the National Academy of Sciences.

[25]  J. Sumida,et al.  Conserved Asp-137 Imparts Flexibility to Tropomyosin and Affects Function* , 2008, Journal of Biological Chemistry.

[26]  J. Jenkins,et al.  Evolutionary distance from human homologs reflects allergenicity of animal food proteins. , 2007, The Journal of allergy and clinical immunology.

[27]  G. Montelione,et al.  Solution NMR structure of the junction between tropomyosin molecules: implications for actin binding and regulation. , 2006, Journal of molecular biology.

[28]  C. Cohen,et al.  Structure of the mid-region of tropomyosin: bending and binding sites for actin. , 2005, Proceedings of the National Academy of Sciences of the United States of America.

[29]  E. Mills,et al.  Stability of the major allergen Brazil nut 2S albumin (Ber e 1) to physiologically relevant in vitro gastrointestinal digestion , 2005, The FEBS journal.

[30]  G. Reese,et al.  Molecular Basis of Arthropod Cross-Reactivity: IgE-Binding Cross-Reactive Epitopes of Shrimp, House Dust Mite and Cockroach Tropomyosins , 2002, International Archives of Allergy and Immunology.

[31]  G. Reese,et al.  Identification of Continuous, Allergenic Regions of the Major Shrimp Allergen Pen a 1 (Tropomyosin) , 2002, International Archives of Allergy and Immunology.

[32]  K H Kim,et al.  Deciphering the design of the tropomyosin molecule , 2001, Proceedings of the National Academy of Sciences of the United States of America.

[33]  Roy L. Fuchs,et al.  Stability of food allergens to digestion in vitro , 1996, Nature Biotechnology.

[34]  T. Darden,et al.  Particle mesh Ewald: An N⋅log(N) method for Ewald sums in large systems , 1993 .

[35]  G. Phillips,et al.  Tropomyosin crystal structure and muscle regulation. , 1986, Journal of molecular biology.

[36]  H. Berendsen,et al.  Molecular dynamics with coupling to an external bath , 1984 .

[37]  W. Kabsch,et al.  Dictionary of protein secondary structure: Pattern recognition of hydrogen‐bonded and geometrical features , 1983, Biopolymers.

[38]  D. Parry Coiled-coils in α-helix-containing proteins: analysis of the residue types within the heptad repeat and the use of these data in the prediction of coiled-coils in other proteins , 1982, Bioscience reports.

[39]  G. Ciccotti,et al.  Numerical Integration of the Cartesian Equations of Motion of a System with Constraints: Molecular Dynamics of n-Alkanes , 1977 .

[40]  T. Schwede,et al.  Protein structure homology modeling using SWISS-MODEL workspace , 2008, Nature Protocols.

[41]  E. Padlan,et al.  Why is there a greater incidence of allergy to the tropomyosin of certain animals than to that of others? , 2007, Medical hypotheses.

[42]  Sergei V Strelkov,et al.  Analysis of alpha-helical coiled coils with the program TWISTER reveals a structural mechanism for stutter compensation. , 2002, Journal of structural biology.

[43]  G. Phillips,et al.  Crystal structure of tropomyosin at 7 Ångstroms resolution , 2000, Proteins.

[44]  R D Appel,et al.  Protein identification and analysis tools in the ExPASy server. , 1999, Methods in molecular biology.

[45]  L. Chiche,et al.  Molecular modeling of coiled-coil alpha-tropomyosin: analysis of staggered and in register helix-helix interactions. , 1993, Protein engineering.