Mechanical stretch induces angiotensinogen expression through PARP1 activation in kidney proximal tubular cells

[1]  A. Boulares,et al.  Poly (ADP‐ribose) polymerase‐1 is a key mediator of liver inflammation and fibrosis , 2014, Hepatology.

[2]  R. Nørregaard,et al.  ROS dependence of cyclooxygenase-2 induction in rats subjected to unilateral ureteral obstruction. , 2014, American journal of physiology. Renal physiology.

[3]  R. Kalluri,et al.  Origin and function of myofibroblasts in kidney fibrosis , 2013, Nature Medicine.

[4]  S. Gharib,et al.  Cellular mechanisms of tissue fibrosis. 3. Novel mechanisms of kidney fibrosis. , 2013, American journal of physiology. Cell physiology.

[5]  Jinu Kim,et al.  Renal nerves drive interstitial fibrogenesis in obstructive nephropathy. , 2013, Journal of the American Society of Nephrology : JASN.

[6]  J. Y. Lim,et al.  Mechanical stretch suppresses BMP4 induction of stem cell adipogenesis via upregulating ERK but not through downregulating Smad or p38. , 2012, Biochemical and biophysical research communications.

[7]  A. G. de Herreros,et al.  The p65 subunit of NF-κB and PARP1 assist Snail1 in activating fibronectin transcription , 2011, Journal of Cell Science.

[8]  Jinu Kim,et al.  Loss of poly(ADP-ribose) polymerase 1 attenuates renal fibrosis and inflammation during unilateral ureteral obstruction. , 2011, American journal of physiology. Renal physiology.

[9]  Tsutomu Inoue,et al.  Fibroblast expression of an IκB dominant-negative transgene attenuates renal fibrosis. , 2010, Journal of the American Society of Nephrology : JASN.

[10]  P. Boor,et al.  Renal fibrosis: novel insights into mechanisms and therapeutic targets , 2010, Nature Reviews Nephrology.

[11]  T. Kirita,et al.  Mechanical stretch enhances NF-kappaB-dependent gene expression and poly(ADP-ribose) synthesis in synovial cells. , 2010, Journal of biochemistry.

[12]  Youhua Liu New insights into epithelial-mesenchymal transition in kidney fibrosis. , 2010, Journal of the American Society of Nephrology : JASN.

[13]  H. Lan,et al.  Angiotensin II Induces Connective Tissue Growth Factor and Collagen I Expression via Transforming Growth Factor–&bgr;–Dependent and –Independent Smad Pathways: The Role of Smad3 , 2009, Hypertension.

[14]  C. Szabó,et al.  Poly(ADP-ribose) polymerase-1 (PARP-1) transcriptionally regulates angiotensin AT2 receptor (AT2R) and AT2R binding protein (ATBP) genes. , 2009, Biochemical pharmacology.

[15]  J. Fitzpatrick,et al.  Exploring mechanisms involved in renal tubular sensing of mechanical stretch following ureteric obstruction. , 2008, American journal of physiology. Renal physiology.

[16]  W. Kraus,et al.  Reciprocal Binding of PARP-1 and Histone H1 at Promoters Specifies Transcriptional Outcomes , 2008, Science.

[17]  S. Desnoyers,et al.  Regulation of poly(ADP-ribose) polymerase-1 (PARP-1) gene expression through the post-translational modification of Sp1: a nuclear target protein of PARP-1 , 2007, BMC Molecular Biology.

[18]  C. Szabó Poly(ADP-ribose) polymerase activation by reactive nitrogen species--relevance for the pathogenesis of inflammation. , 2006, Nitric oxide : biology and chemistry.

[19]  Youhua Liu,et al.  Renal fibrosis: new insights into the pathogenesis and therapeutics. , 2006, Kidney international.

[20]  Shunqiang Li,et al.  Angiotensin II and EGF receptor cross-talk in chronic kidney diseases: a new therapeutic approach , 2005, Nature Medicine.

[21]  J. Egido,et al.  Angiotensin II Activates the Smad Pathway in Vascular Smooth Muscle Cells by a Transforming Growth Factor-β–Independent Mechanism , 2005, Circulation.

[22]  A. Roberts,et al.  Targeted disruption of TGF-beta1/Smad3 signaling protects against renal tubulointerstitial fibrosis induced by unilateral ureteral obstruction. , 2003, The Journal of clinical investigation.

[23]  K. Miura,et al.  Attenuation of renal fibrosis by proteasome inhibition in rat obstructive nephropathy: possible role of nuclear factor kappaB. , 2003, International journal of molecular medicine.

[24]  J. Egido,et al.  Connective Tissue Growth Factor Is a Mediator of Angiotensin II–Induced Fibrosis , 2003, Circulation.

[25]  M. Moskowitz,et al.  Poly(ADP‐ribose) polymerase‐1 activity promotes NF‐κB‐driven transcription and microglial activation: implication for neurodegenerative disorders , 2003, Journal of neurochemistry.

[26]  Marta Ruiz-Ortega,et al.  Angiotensin II regulates the synthesis of proinflammatory cytokines and chemokines in the kidney. , 2002, Kidney international. Supplement.

[27]  M. Hottiger,et al.  The functional role of poly(ADP-ribose)polymerase 1 as novel coactivator of NF-κB in inflammatory disorders , 2002, Cellular and Molecular Life Sciences CMLS.

[28]  M. Covic,et al.  The Enzymatic and DNA Binding Activity of PARP-1 Are Not Required for NF-κB Coactivator Function* , 2001, The Journal of Biological Chemistry.

[29]  R. Ardaillou,et al.  Angiotensin II activates collagen type I gene in the renal cortex and aorta of transgenic mice through interaction with endothelin and TGF-beta. , 2001, Journal of the American Society of Nephrology : JASN.

[30]  J. Egido,et al.  Angiotensin II and renal fibrosis. , 2001, Hypertension.

[31]  C. D. Sharp,et al.  Poly ADP Ribose-Polymerase Inhibitors Prevent the Upregulation of ICAM-1 and E-selectin in Response to Th1 Cytokine Stimulation , 2001, Inflammation.

[32]  D. Poppas,et al.  Interaction of nitric oxide and transforming growth factor-beta1 induced by angiotensin II and mechanical stretch in rat renal tubular epithelial cells. , 2000, The Journal of urology.

[33]  V. Rotter,et al.  A Fast Signal–Induced Activation of Poly(Adp-Ribose) Polymerase , 2000, The Journal of cell biology.

[34]  Y. Toya,et al.  Activation of angiotensinogen gene in cardiac myocytes by angiotensin II and mechanical stretch. , 1998, American journal of physiology. Regulatory, integrative and comparative physiology.

[35]  S. Klahr,et al.  Enalapril decreases nuclear factor κB activation in the kidney with ureteral obstruction: Rapid Communication , 1997 .

[36]  S. Ricardo,et al.  Antioxidant expression in experimental hydronephrosis: role of mechanical stretch and growth factors. , 1997, The American journal of physiology.

[37]  D E Ingber,et al.  Mechanotransduction across the cell surface and through the cytoskeleton. , 1993, Science.

[38]  M. Schwartz,et al.  Spreading of human endothelial cells on fibronectin or vitronectin triggers elevation of intracellular free calcium , 1993, The Journal of cell biology.

[39]  T. Maniatis,et al.  Generation of p50 subunit of NF-kB by processing of p105 through an ATP-dependent pathway , 1991, Nature.

[40]  D. Ron,et al.  Transcriptional regulation of hepatic angiotensinogen gene expression by the acute-phase response , 1990, Molecular and Cellular Endocrinology.

[41]  D. Ron,et al.  A family of constitutive C/EBP‐like DNA binding proteins attenuate the IL‐1 alpha induced, NF kappa B mediated trans‐activation of the angiotensinogen gene acute‐phase response element. , 1990, The EMBO journal.

[42]  M. Sporn,et al.  Suppression of experimental glomerulonephritis by antiserum against transforming growth factor β1 , 1990, Nature.

[43]  J. Ingelfinger,et al.  In situ hybridization evidence for angiotensinogen messenger RNA in the rat proximal tubule. An hypothesis for the intrarenal renin angiotensin system. , 1990, The Journal of clinical investigation.

[44]  T. Haverty,et al.  Characterization of a renal tubular epithelial cell line which secretes the autologous target antigen of autoimmune experimental interstitial nephritis , 1988, The Journal of cell biology.

[45]  V. Ed,et al.  The renal hemodynamic response to chronic unilateral complete ureteral occlusion. , 1970 .

[46]  H. S. Kim,et al.  Reduced angiotensinogen expression attenuates renal interstitial fibrosis in obstructive nephropathy in mice. , 1999, The Journal of clinical investigation.

[47]  S. Klahr,et al.  Rapid communication. Enalapril decreases nuclear factor kappa B activation in the kidney with ureteral obstruction. , 1997, Kidney international.

[48]  Histone-Specific Adaptations,et al.  Regulation of Poly(ADP-ribose) Polymerase , 1991 .

[49]  E. Vaughan,et al.  The renal hemodynamic response to chronic unilateral complete ureteral occlusion. , 1970, Investigative urology.