Two New Oleanane-type Saponins from Hydrocotyle multifida

A phytochemical study of a Venezuelan species Hydrocotyle multifida led to the isolation of five oleanane-type glycosides: two previously undescribed and three known ones. Their structures were established by 2D NMR spectroscopic techniques and mass spectrometry as 3-O-β-D-galactopyranosyl-(1→2)-[α-L-arabinopyranosyl-(1→3)]-β-D-glucuronopyranosyloleanolic acid and 3-O-β-D-glucopyranosyl-(1→2)-β-D-glucopyranosyl-(1→2)-β-D-glucuronopyrano-syloleanolic acid. These results represent a significative contribution to the chemotaxonomy of the Hydrocotyle genus.

[1]  Nampoina Andriamisaina,et al.  Phytochemistry of Weigela x “kosteriana variegata” (Caprifoliaceae) , 2018 .

[2]  C. Long,et al.  Ethnobotanical study on medicinal plants used by Maonan people in China , 2015, Journal of Ethnobiology and Ethnomedicine.

[3]  M. Lacaille‐Dubois,et al.  Triterpenoid saponins from Hydrocotyle bonariensis Lam. , 2012, Phytochemistry.

[4]  M. Lacaille‐Dubois,et al.  New Triterpenoid and Ergostane Glycosides from the Leaves of Hydrocotyle umbellata L. , 2011 .

[5]  M. Lacaille‐Dubois,et al.  Triterpenoidal saponins from Hydrocotyle bonariensis , 2010 .

[6]  G. Plunkett,et al.  The demise of subfamily Hydrocotyloideae (Apiaceae) and the re-alignment of its genera across the entire order Apiales. , 2009, Molecular phylogenetics and evolution.

[7]  T. Miyase,et al.  Hydrocotylosides I-VII, new oleanane saponins from hydrocotylesibthorpioides. , 2004, Journal of natural products.

[8]  B. Briceño,et al.  Catálogo abreviado de las plantas con flores de los páramos de Venezuela. Parte I. Dicotiledóneas (Magnoliopsida) , 2002 .

[9]  A. Díaz-Lanza,et al.  Four new triterpenoid saponins from the roots of Bupleurum rigidum. , 2000, Journal of natural products.

[10]  A. Fiorentino,et al.  Oleanane glycosides from Hydrocotyle ranunculoides. , 1994, Phytochemistry.

[11]  H. Okabe,et al.  Gas-liquid chromatographic separation of aldose enantiomers as trimethylsilyl ethers of methyl 2-(polyhydroxyalkyl)thiazolidine-4(R)-carboxylates , 1987 .

[12]  H. Okabe,et al.  Studies on the constituents of Momordica cochinchinensis SPRENG. II: Isolation and characterization of the root saponins, momordins I, II and III , 1985 .

[13]  O. Tanaka,et al.  Saponins from Chinese medicinal plants. (I). Isolation and structures of hemslosides. , 1984, Planta medica.