Chronic Fatigue Syndrome: A Review

Chronic fatigue syndrome (CFS) is an illness characterized by disabling fatigue of atleast 6 months accompanied by several other secondary symptoms. Till date there is no approved treatment available in the market. The diagnosis is based on symptoms and no specific diagnostic tests are yet exist. CFS is a heterogeneous condition with multifactorial etiology. Immunological, Infectious, Sleep, Neuroendocrine, oxidative stress and Central nervous system mechanisms have been investigated but still etiology of CFS is not clear. Our review will summarize a current status of Pathophysiology and treatment of chronic fatigue syndrome.