Fine mapping of type 1 diabetes susceptibility loci and evidence for colocalization of causal variants with lymphoid gene enhancers
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Manolis Kellis | Anshul Kundaje | Wei-Min Chen | Ellen Schofield | Chris Wallace | Panos Deloukas | Aaron R Quinlan | Premanand Achuthan | Mark J Daly | Mary D Fortune | Stephen S Rich | Josyf C Mychaleckyj | Neil M Walker | Helen Stevens | Mary D. Fortune | John A Todd | Jeffrey C Barrett | Michal Szpak | P. Deloukas | M. Daly | Manolis Kellis | A. Kundaje | J. Todd | J. Barrett | H. Stevens | N. Walker | C. Wallace | Wei-Min Chen | L. D. Ward | A. Quinlan | S. Rich | P. Concannon | O. Burren | J. Cooper | Hui Guo | S. Onengut-Gumuscu | N. Cooper | J. Mychaleckyj | E. Farber | J. Bonnie | M. Szpak | E. Schofield | P. Achuthan | Jason D Cooper | Hui Guo | Oliver Burren | Patrick Concannon | Suna Onengut-Gumuscu | Nick J Cooper | Emily Farber | Jessica K Bonnie | Lucas D Ward | Emily Farber
[1] A. Grüters,et al. Analysis of the Wilms' tumor suppressor gene (WT1) in patients 46,XY disorders of sex development. , 2011, The Journal of clinical endocrinology and metabolism.
[2] F. Vannberg,et al. GENETICS OF GENE EXPRESSION IN PRIMARY IMMUNE CELLS IDENTIFIES CELL-SPECIFIC MASTER REGULATORS AND ROLES OF HLA ALLELES , 2012, Nature Genetics.
[3] Mark I McCarthy,et al. Remapping the insulin gene/IDDM2 locus in type 1 diabetes. , 2004, Diabetes.
[4] Sarah Edkins,et al. Dense genotyping identifies and localizes multiple common and rare variant association signals in celiac disease , 2011, Nature Genetics.
[5] A. Ashworth,et al. Unbiased analysis of potential targets of breast cancer susceptibility loci by Capture Hi-C , 2014, Genome research.
[6] R. A. Bailey,et al. Robust associations of four new chromosome regions from genome-wide analyses of type 1 diabetes , 2007, Nature Genetics.
[7] M. Peters,et al. Systematic identification of trans eQTLs as putative drivers of known disease associations , 2013, Nature Genetics.
[8] J. Todd,et al. Genome-Wide Scan for Linkage to Type 1 Diabetes in 2,496 Multiplex Families From the Type 1 Diabetes Genetics Consortium , 2009, Diabetes.
[9] Cisca Wijmenga,et al. Shared and distinct genetic variants in type 1 diabetes and celiac disease. , 2008, The New England journal of medicine.
[10] Kasper Lage,et al. Pervasive Sharing of Genetic Effects in Autoimmune Disease , 2011, PLoS genetics.
[11] Constantin Polychronakos,et al. A Genome-Wide Meta-Analysis of Six Type 1 Diabetes Cohorts Identifies Multiple Associated Loci , 2011, PLoS genetics.
[12] H. Krude,et al. Diabetes caused by insulin gene (INS) deletion: clinical characteristics of homozygous and heterozygous individuals. , 2011, European journal of endocrinology.
[13] Alan Aldrich,et al. Designing and implementing sample and data collection for an international genetics study: the Type 1 Diabetes Genetics Consortium (T1DGC) , 2010, Clinical trials.
[14] K. Raile,et al. Associations Between Media Consumption Habits, Physical Activity, Socioeconomic Status, and Glycemic Control in Children, Adolescents, and Young Adults With Type 1 Diabetes , 2011, Diabetes Care.
[15] Jon Wakefield,et al. Bayes factors for genome‐wide association studies: comparison with P‐values , 2009, Genetic epidemiology.
[16] Emmanouil Collab. A map of human genome variation from population-scale sequencing , 2011, Nature.
[17] C. Power,et al. Cohort profile: 1958 British birth cohort (National Child Development Study). , 2006, International journal of epidemiology.
[18] Peggy Hall,et al. The NHGRI GWAS Catalog, a curated resource of SNP-trait associations , 2013, Nucleic Acids Res..
[19] Helen Schuilenburg,et al. Information for : Genome-wide association study and meta-analysis indicates that over 40 loci affect risk of type 1 diabetes , 2009 .
[20] Mark I. McCarthy,et al. Pancreatic islet enhancer clusters enriched in type 2 diabetes risk–associated variants , 2013, Nature Genetics.
[21] Matthew Hardy,et al. Cell-specific protein phenotypes for the autoimmune locus IL2RA using a genotype-selectable human bioresource , 2009, Nature Genetics.
[22] John A. Todd,et al. Metagenomics and Personalized Medicine , 2011, Cell.
[23] M. Kester,et al. Circulating Preproinsulin Signal Peptide–Specific CD8 T Cells Restricted by the Susceptibility Molecule HLA-A24 Are Expanded at Onset of Type 1 Diabetes and Kill β-Cells , 2012, Diabetes.
[24] Jasmin Divers,et al. Population Structure of Hispanics in the United States: The Multi-Ethnic Study of Atherosclerosis , 2012, PLoS genetics.
[25] T. Meehan,et al. An atlas of active enhancers across human cell types and tissues , 2014, Nature.
[26] Josyf Mychaleckyj,et al. Robust relationship inference in genome-wide association studies , 2010, Bioinform..
[27] J. Shaw,et al. Follow-up report on the diagnosis of diabetes mellitus. , 2003, Diabetes care.
[28] D. Reich,et al. Principal components analysis corrects for stratification in genome-wide association studies , 2006, Nature Genetics.
[29] Jake K. Byrnes,et al. Bayesian refinement of association signals for 14 loci in 3 common diseases , 2012, Nature Genetics.
[30] M. Gobbi,et al. Analysis of hundreds of cis-regulatory landscapes at high resolution in a single, high-throughput experiment , 2014, Nature Genetics.
[31] Yun Li,et al. METAL: fast and efficient meta-analysis of genomewide association scans , 2010, Bioinform..
[32] Wei-Min Chen,et al. A generalized family-based association test for dichotomous traits. , 2009, American journal of human genetics.
[33] B. Köhler,et al. DSD and Professionalism from a Multilateral View: Supplementing the Consensus Statement on the Basis of a Qualitative Survey , 2012, Advances in urology.
[34] C. Wallace,et al. Bayesian Test for Colocalisation between Pairs of Genetic Association Studies Using Summary Statistics , 2013, PLoS genetics.
[35] M. Dattani,et al. Increased transactivation associated with SOX3 polyalanine tract deletion in a patient with hypopituitarism. , 2011, The Journal of clinical endocrinology and metabolism.
[36] J. Karam,et al. A Polymorphic Locus Near the Human Insulin Gene Is Associated with Insulin-dependent Diabetes Melliitus , 1984, Diabetes.
[37] Simon C. Potter,et al. Genome-wide association study of 14,000 cases of seven common diseases and 3,000 shared controls , 2007, Nature.
[38] Nicola K. Wilson,et al. Long-range DNA looping and gene expression analyses identify DEXI as an autoimmune disease candidate gene , 2011, Human molecular genetics.
[39] A. Grüters,et al. Metformin and placebo therapy both improve weight management and fasting insulin in obese insulin-resistant adolescents: a prospective, placebo-controlled, randomized study. , 2010, European journal of endocrinology.
[40] A. Raftery. Approximate Bayes factors and accounting for model uncertainty in generalised linear models , 1996 .
[41] Eli Stahl,et al. High density genetic mapping identifies new susceptibility loci for rheumatoid arthritis , 2012, Nature Genetics.
[42] R. Andrews,et al. Innate Immune Activity Conditions the Effect of Regulatory Variants upon Monocyte Gene Expression , 2014, Science.
[43] Manuel A. R. Ferreira,et al. PLINK: a tool set for whole-genome association and population-based linkage analyses. , 2007, American journal of human genetics.
[44] Daniel Rios,et al. Bioinformatics Applications Note Databases and Ontologies Deriving the Consequences of Genomic Variants with the Ensembl Api and Snp Effect Predictor , 2022 .
[45] David C. Wilson,et al. Host-microbe interactions have shaped the genetic architecture of inflammatory bowel disease , 2012, Nature.
[46] S. Genuth. Lowering the criterion for impaired fasting glucose is in order. , 2003, Diabetes care.
[47] R. Handsaker,et al. Structural haplotypes and recent evolution of the human 17q21.31 region , 2012, Nature Genetics.
[48] Daniel J. Gaffney,et al. Dense fine-mapping study identifies new susceptibility loci for primary biliary cirrhosis , 2012, Nature Genetics.
[49] F. Svensson,et al. Two genes encoding immune-regulatory molecules (LAG3 and IL7R) confer susceptibility to multiple sclerosis , 2005, Genes and Immunity.
[50] Dmitri V Zaykin,et al. P‐value based analysis for shared controls design in genome‐wide association studies , 2010, Genetic epidemiology.
[51] T. Meissner,et al. Genetic and clinical characteristics of patients with HNF1A gene variations from the German-Austrian DPV database. , 2011, European journal of endocrinology.
[52] Tariq Ahmad,et al. Meta-analysis identifies 29 additional ulcerative colitis risk loci, increasing the number of confirmed associations to 47 , 2011, Nature Genetics.
[53] H. Biebermann,et al. Screening chromosomal aberrations by array comparative genomic hybridization in 80 patients with congenital hypothyroidism and thyroid dysgenesis. , 2010, The Journal of clinical endocrinology and metabolism.
[54] Manolis Kellis,et al. HaploReg: a resource for exploring chromatin states, conservation, and regulatory motif alterations within sets of genetically linked variants , 2011, Nucleic Acids Res..
[55] C. Wallace. Wilcoxon based gene set enrichment analysis , 2013 .
[56] Martin Vingron,et al. A trans-acting locus regulates an anti-viral expression network and type 1 diabetes risk , 2010, Nature.