Up-regulation of 12(S)-lipoxygenase induces a migratory phenotype in colorectal cancer cells
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W. Berger | B. Marian | S. Stättner | T. Klampfl | M. Klimpfinger | C. Heinzle | P. Krieg | G. Fürstenberger | J. Karner | L. Mager | E. Bogner | W. Bednar | D. Massudom | I. Kalny
[1] W. Jäger,et al. NF-κB mediates the 12(S)-HETE-induced endothelial to mesenchymal transition of lymphendothelial cells during the intravasation of breast carcinoma cells , 2011, British Journal of Cancer.
[2] D. Steinhilber,et al. Lipoxygenase mediates invasion of intrametastatic lymphatic vessels and propagates lymph node metastasis of human mammary carcinoma xenografts in mouse. , 2011, The Journal of clinical investigation.
[3] Jeffrey S. Morris,et al. Profiling Lipoxygenase Metabolism in Specific Steps of Colorectal Tumorigenesis , 2010, Cancer Prevention Research.
[4] S. Spiegl-Kreinecker,et al. Fibroblast growth factor receptor 3-IIIc mediates colorectal cancer growth and migration , 2010, British Journal of Cancer.
[5] D. Svergun,et al. Human platelet 12-lipoxygenase, new findings about its activity, membrane binding and low-resolution structure. , 2008, Journal of molecular biology.
[6] G. Christofori,et al. Increased tumor cell dissemination and cellular senescence in the absence of β1‐integrin function , 2007, The EMBO journal.
[7] W. Tan,et al. Associations of functional polymorphisms in cyclooxygenase-2 and platelet 12-lipoxygenase with risk of occurrence and advanced disease status of colorectal cancer. , 2007, Carcinogenesis.
[8] B. Marian,et al. Assessing 12(S)-lipoxygenase inhibitory activity using colorectal cancer cells overexpressing the enzyme. , 2007, Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association.
[9] A. Habenicht,et al. What are cyclooxygenases and lipoxygenases doing in the driver's seat of carcinogenesis? , 2006, International journal of cancer.
[10] F. Cianchi,et al. Inhibition of 5-lipoxygenase by MK886 augments the antitumor activity of celecoxib in human colon cancer cells , 2006, Molecular Cancer Therapeutics.
[11] V. O’Donnell,et al. Inflammation and immune regulation by 12/15-lipoxygenases. , 2006, Progress in lipid research.
[12] H. Kühn. Biologic relevance of lipoxygenase isoforms in atherogenesis. , 2005 .
[13] Gerhard Christofori,et al. Cell adhesion and signalling by cadherins and Ig-CAMs in cancer , 2004, Nature Reviews Cancer.
[14] D. Nie,et al. Eicosanoid regulation of angiogenesis in tumors. , 2004, Seminars in thrombosis and hemostasis.
[15] K. Honn,et al. Overexpression of platelet-type 12-lipoxygenase promotes tumor cell survival by enhancing alpha(v)beta(3) and alpha(v)beta(5) integrin expression. , 2003, Cancer research.
[16] Lei Zhao,et al. Lipoxygenase genes and their targeted disruption. , 2002, Prostaglandins & other lipid mediators.
[17] H. Kuhn,et al. Mammalian arachidonate 15-lipoxygenases structure, function, and biological implications. , 2002, Prostaglandins & other lipid mediators.
[18] T. Adrian,et al. 12‐lipoxygenase metabolite 12(S)‐HETE stimulates human pancreatic cancer cell proliferation via protein tyrosine phosphorylation and ERK activation , 2001, International journal of cancer.
[19] B. Wong,et al. 12-Lipoxygenase inhibition induced apoptosis in human gastric cancer cells. , 2001, Carcinogenesis.
[20] D. Grignon,et al. Expression, subcellular localization and putative function of platelet‐type 12‐lipoxygenase in human prostate cancer cell lines of different metastatic potential , 2000, International journal of cancer.
[21] D. Nie,et al. Eicosanoid Regulation of Angiogenesis in Human Prostate Carcinoma and Its Therapeutic Implications , 2000, Annals of the New York Academy of Sciences.
[22] R. DuBois,et al. Review article: cyclooxygenase – a target for colon cancer prevention , 2000, Alimentary pharmacology & therapeutics.
[23] J. Drazen,et al. The biology of 5-lipoxygenase: function, structure, and regulatory mechanisms. , 1999, Proceedings of the Association of American Physicians.
[24] A. Brash. Lipoxygenases: Occurrence, Functions, Catalysis, and Acquisition of Substrate* , 1999, The Journal of Biological Chemistry.
[25] X. Ding,et al. Lipoxygenase inhibitors abolish proliferation of human pancreatic cancer cells. , 1999, Biochemical and biophysical research communications.
[26] E. Raso,et al. Multiple use of a signal transduction pathway in tumor cell invasion. , 1996, Anticancer research.
[27] K. Honn,et al. Arachidonate lipoxygenases as essential regulators of cell survival and apoptosis. , 1996, Proceedings of the National Academy of Sciences of the United States of America.
[28] K. Kashfi,et al. The effect of leukotrienes B and selected HETEs on the proliferation of colon cancer cells. , 1996, Biochimica et biophysica acta.
[29] T. Yoshimoto,et al. Arachidonate 12-lipoxygenase. , 1995, Journal of lipid mediators and cell signalling.
[30] D. Grignon,et al. Elevated 12-lipoxygenase mRNA expression correlates with advanced stage and poor differentiation of human prostate cancer. , 1995, Urology.
[31] Bonnie F. Sloane,et al. A lipoxygenase metabolite, 12-(S)-HETE, stimulates protein kinase C-mediated release of cathepsin B from malignant cells. , 1994, Experimental cell research.
[32] J. Tímár,et al. Tumor cell-derived 12(S)-hydroxyeicosatetraenoic acid induces microvascular endothelial cell retraction. , 1994, Cancer research.
[33] G. Wong,et al. Quercetin and rutin as inhibitors of azoxymethanol-induced colonic neoplasia. , 1991, Carcinogenesis.
[34] W. Bodmer,et al. Low expression of collagen receptors in moderate and poorly differentiated colorectal adenocarcinomas. , 1990, British Journal of Cancer.
[35] D. Grignon,et al. Increased metastatic potential in human prostate carcinoma cells by overexpression of arachidonate 12-lipoxygenase , 2004, Clinical & Experimental Metastasis.
[36] K. Honn,et al. 12(S)-HETE, pleiotropic functions, multiple signaling pathways. , 2002, Advances in experimental medicine and biology.
[37] E. Raso,et al. 12-lipoxygenase expression in human melanoma cell lines. , 1999, Advances in experimental medicine and biology.
[38] W. Lehmann,et al. Different expression of prostaglandin-H synthase isozymes and lipoxygenases during multistage carcinogenesis in mouse skin. , 1997, Advances in experimental medicine and biology.
[39] K. Honn,et al. Enhanced endothelial cell retraction mediated by 12(S)-HETE: a proposed mechanism for the role of platelets in tumor cell metastasis. , 1994, Experimental cell research.
[40] G. Wong,et al. The effect of dietary quercetin and rutin on AOM-induced acute colonic epithelial abnormalities in mice fed a high-fat diet. , 1993, Nutrition and cancer.