A Nondestructive Diagnostic Modeling for Muscular Dysfunction of Human Pharynx Using Finite Element Method

Pharynx is a organ which transports food into the esophagus through peristaltic motion (repeat of contraction and expansion movement) and functions as an air passage. In this study, a structural change of human pharynx caused by muscular dysfunction is analyzed by a biomechanical model using CT and FEM(finite element method). For the biomechanical model, a loading condition is assumed so that equal internal pressure loaded sequentially to the inside of pharyngeal tissue. In order to analyze the pharyngeal muscular dysfunction by the biomechanical model, the pharyngeal dysfunctions are classified into 3 cases in the clinical complication by neuromuscular symptoms such as pharyngeal dysfunction after stroke. Those cases frequently show a change of material property and we investigated muscular tissue stiffness, deformation of cross sectional area of the pharynx by increasing the stiffness to 25%, 50%, 75% on the basis of stress-strain relationship of the pharyngeal tissue in each case. With three-dimensional reconstruction of pharyngeal structure using FEM and the optimization process by using inverse dynamic approach, the biomechanical model of the human pharynx is implemented and the muscular dysfunction is simulated.

[1]  G. G. Stokes "J." , 1890, The New Yale Book of Quotations.

[2]  B. Wolf,et al.  Simultaneous cineradiographic and manometric study of the pharynx, hypopharynx, and cervical esophagus. , 1966, Gastroenterology.

[3]  A. Dachman,et al.  Normal erect swallowing. Normal function and incidence of variations. , 1985, Investigative radiology.

[4]  D. Prakash Dysphagia in acute stroke. , 1987, British medical journal.

[5]  F. McConnel,et al.  Analysis of pressure generation and bolus transit during pharyngeal swallowing , 1988, The Laryngoscope.

[6]  P. Pouderoux,et al.  Deglutitive tongue force modulation by volition, volume, and viscosity in humans. , 1995, Gastroenterology.

[7]  J Chen,et al.  Three-dimensional modeling of the oropharynx during swallowing. , 1995, Radiology.

[8]  H M Finestone,et al.  Malnutrition in stroke patients on the rehabilitation service and at follow-up: prevalence and predictors. , 1995, Archives of physical medicine and rehabilitation.

[9]  P. Kahrilas,et al.  Oropharyngeal accommodation to swallow volume. , 1996, Gastroenterology.

[10]  Evaluation of the viscoelastic properties of pharyngeal tissue. , 1998, Tissue engineering.

[11]  K Rim,et al.  Pharyngeal Pressure Analysis by the Finite Element Method during Liquid Bolus Swallow , 2000, The Annals of otology, rhinology, and laryngology.

[12]  P. Kahrilas,et al.  Food intake by maneuver; An extreme compensation for impaired swallowing , 1992, Dysphagia.

[13]  J. Brasseur,et al.  Interpretation of intraluminal manometric measurements in terms of swallowing mechanics , 2006, Dysphagia.