Association of increased visfatin/PBEF/NAMPT circulating concentrations and gene expression levels in peripheral blood cells with lipid metabolism and fatty liver in human morbid obesity.

[1]  D. D. de Luis,et al.  Circulating visfatin in obese non-diabetic patients in relation to cardiovascular risk factors, insulin resistance, and adipocytokines: a contradictory piece of the puzzle. , 2010, Nutrition.

[2]  O. Izaola,et al.  Influence of Visfatin on Histopathological Changes of Non-alcoholic Fatty Liver Disease , 2009, Digestive Diseases and Sciences.

[3]  G. Frühbeck,et al.  Increased adipose tissue expression of lipocalin-2 in obesity is related to inflammation and matrix metalloproteinase-2 and metalloproteinase-9 activities in humans , 2009, Journal of Molecular Medicine.

[4]  Y. Liu,et al.  Correlation of circulating full‐length visfatin (PBEF/NAMPT) with metabolic parameters in subjects with and without diabetes: a cross‐sectional study , 2008, Clinical endocrinology.

[5]  H. Gong,et al.  Increased serum visfatin in patients with metabolic syndrome and carotid atherosclerosis , 2008, Clinical endocrinology.

[6]  S. Visvikis-Siest,et al.  Visfatin, low‐grade inflammation and body mass index (BMI) , 2008, Clinical endocrinology.

[7]  E. Cereda,et al.  Epicardial fat thickness: relationship with plasma visfatin and plasminogen activator inhibitor-1 levels in visceral obesity. , 2008, Nutrition, metabolism, and cardiovascular diseases : NMCD.

[8]  Bohan Wang,et al.  Hypoxia in adipose tissue: a basis for the dysregulation of tissue function in obesity? , 2008, British Journal of Nutrition.

[9]  M. Fasshauer,et al.  Visfatin/PBEF/Nampt: structure, regulation and potential function of a novel adipokine. , 2008, Clinical science.

[10]  O. Leo,et al.  Pharmacological Inhibition of Nicotinamide Phosphoribosyltransferase/Visfatin Enzymatic Activity Identifies a New Inflammatory Pathway Linked to NAD , 2008, PloS one.

[11]  M. Czech,et al.  Adipocyte dysfunctions linking obesity to insulin resistance and type 2 diabetes , 2008, Nature Reviews Molecular Cell Biology.

[12]  W. Sheu,et al.  Effect of Weight Loss on Proinflammatory State of Mononuclear Cells in Obese Women , 2008, Obesity.

[13]  H. Tilg,et al.  Inflammatory Mechanisms in the Regulation of Insulin Resistance , 2008, Molecular medicine.

[14]  S. Weisberg,et al.  Obesity in C57BL/6J mice is characterized by adipose tissue hypoxia and cytotoxic T-cell infiltration , 2008, International Journal of Obesity.

[15]  Min You,et al.  Mammalian sirtuin 1 is involved in the protective action of dietary saturated fat against alcoholic fatty liver in mice. , 2008, The Journal of nutrition.

[16]  H. Tilg,et al.  Role of adiponectin and PBEF/visfatin as regulators of inflammation: involvement in obesity-associated diseases. , 2008, Clinical science.

[17]  A. Baranova,et al.  Adipokines and cytokines in non‐alcoholic fatty liver disease , 2007, Alimentary pharmacology & therapeutics.

[18]  M. Blüher,et al.  Molecular characteristics of serum visfatin and differential detection by immunoassays. , 2007, The Journal of clinical endocrinology and metabolism.

[19]  J. Milbrandt,et al.  Nampt/PBEF/Visfatin regulates insulin secretion in beta cells as a systemic NAD biosynthetic enzyme. , 2007, Cell metabolism.

[20]  N. Kohno,et al.  Circulating visfatin level is correlated with inflammation, but not with insulin resistance , 2007, Clinical endocrinology.

[21]  R. Nazar,et al.  Borrowing from Biology , 2007, Science.

[22]  C. Tsigos,et al.  Visfatin, TNF-α and IL-6 mRNA Expression is Increased in Mononuclear Cells from Type 2 Diabetic Women , 2007, Hormone and metabolic research = Hormon- und Stoffwechselforschung = Hormones et metabolisme.

[23]  Jianping Ye,et al.  Hypoxia is a potential risk factor for chronic inflammation and adiponectin reduction in adipose tissue of ob/ob and dietary obese mice. , 2007, American journal of physiology. Endocrinology and metabolism.

[24]  H. Osago,et al.  Elevation of Cellular NAD Levels by Nicotinic Acid and Involvement of Nicotinic Acid Phosphoribosyltransferase in Human Cells* , 2007, Journal of Biological Chemistry.

[25]  Bohan Wang,et al.  Dysregulation of the expression and secretion of inflammation-related adipokines by hypoxia in human adipocytes , 2007, Pflügers Archiv - European Journal of Physiology.

[26]  Lulu Chen,et al.  The expression of SIRT1 in nonalcoholic fatty liver disease induced by high‐fat diet in rats , 2007, Liver international : official journal of the International Association for the Study of the Liver.

[27]  Lulu Chen,et al.  [Effects of calorie restriction on SIRT1 expression in liver of nonalcoholic fatty liver disease: experiment with rats]. , 2007, Zhonghua yi xue za zhi.

[28]  J. Flier,et al.  The adipocyte as an active participant in energy balance and metabolism. , 2007, Gastroenterology.

[29]  E. Mariman,et al.  The circulating PBEF/NAMPT/visfatin level is associated with a beneficial blood lipid profile , 2007, Pflügers Archiv - European Journal of Physiology.

[30]  M. Matsuda,et al.  Adipose Tissue Hypoxia in Obesity and Its Impact on Adipocytokine Dysregulation , 2007, Diabetes.

[31]  M. Elisaf,et al.  Increased plasma levels of visfatin/pre-B cell colony-enhancing factor in obese and overweight patients with metabolic syndrome , 2007, Journal of endocrinological investigation.

[32]  S. Imai,et al.  The regulation of nicotinamide adenine dinucleotide biosynthesis by Nampt/PBEF/visfatin in mammals , 2007, Current opinion in gastroenterology.

[33]  S. Tonstad,et al.  Increased Expression of Visfatin in Macrophages of Human Unstable Carotid and Coronary Atherosclerosis: Possible Role in Inflammation and Plaque Destabilization , 2007, Circulation.

[34]  Bounleut Phanavanh,et al.  Human visfatin expression: relationship to insulin sensitivity, intramyocellular lipids, and inflammation. , 2007, The Journal of clinical endocrinology and metabolism.

[35]  E. Randell,et al.  Serum visfatin concentrations are positively correlated with serum triacylglycerols and down-regulated by overfeeding in healthy young men. , 2007, The American journal of clinical nutrition.

[36]  A. Kaser,et al.  Visfatin, an Adipocytokine with Proinflammatory and Immunomodulating Properties1 , 2007, The Journal of Immunology.

[37]  C. Block,et al.  Mechanisms linking obesity with cardiovascular disease , 2006, Nature.

[38]  M. Marescotti,et al.  A Visfatin Promoter Polymorphism Is Associated with Low‐Grade Inflammation and Type 2 Diabetes , 2006, Obesity.

[39]  Max Costa,et al.  Hypoxia-Inducible Factor-1 (HIF-1) , 2006, Molecular Pharmacology.

[40]  M. Matsuda,et al.  Visfatin in adipocytes is upregulated by hypoxia through HIF1alpha-dependent mechanism. , 2006, Biochemical and biophysical research communications.

[41]  J. Fernández-Real,et al.  Serum Visfatin Increases With Progressive β-Cell Deterioration , 2006, Diabetes.

[42]  H. Tilg,et al.  Nonalcoholic fatty liver disease: Cytokine-adipokine interplay and regulation of insulin resistance. , 2006, Gastroenterology.

[43]  R. Vettor,et al.  Reduced plasma visfatin/pre-B cell colony-enhancing factor in obesity is not related to insulin resistance in humans. , 2006, The Journal of clinical endocrinology and metabolism.

[44]  M. Yoo,et al.  Hypoxic induction of human visfatin gene is directly mediated by hypoxia‐inducible factor‐1 , 2006, FEBS letters.

[45]  M. Wolzt,et al.  Increased plasma visfatin concentrations in morbidly obese subjects are reduced after gastric banding. , 2006, The Journal of clinical endocrinology and metabolism.

[46]  M. Laakso,et al.  Visfatin is an adipokine, but it is not regulated by thiazolidinediones. , 2006, The Journal of clinical endocrinology and metabolism.

[47]  R. Busse,et al.  Macrophages in human visceral adipose tissue: increased accumulation in obesity and a source of resistin and visfatin , 2006, Diabetologia.

[48]  M. Fasshauer,et al.  Plasma visfatin concentrations and fat depot-specific mRNA expression in humans. , 2005, Diabetes.

[49]  M. Matsuda,et al.  Visfatin: A Protein Secreted by Visceral Fat That Mimics the Effects of Insulin , 2005, Science.

[50]  S. Imai,et al.  The NAD Biosynthesis Pathway Mediated by Nicotinamide Phosphoribosyltransferase Regulates Sir2 Activity in Mammalian Cells* , 2004, Journal of Biological Chemistry.

[51]  A. Aljada,et al.  Increased plasma concentration of macrophage migration inhibitory factor (MIF) and MIF mRNA in mononuclear cells in the obese and the suppressive action of metformin. , 2004, The Journal of clinical endocrinology and metabolism.

[52]  A. Aljada,et al.  Circulating Mononuclear Cells in the Obese Are in a Proinflammatory State , 2004, Circulation.

[53]  G. Assmann,et al.  Raising high-density lipoprotein cholesterol with reduction of cardiovascular risk: the role of nicotinic acid – a position paper developed by the European Consensus Panel on HDL-C* , 2004, Current medical research and opinion.

[54]  J. Marshall,et al.  Pre-B cell colony-enhancing factor inhibits neutrophil apoptosis in experimental inflammation and clinical sepsis. , 2004, The Journal of clinical investigation.

[55]  J. Shaw,et al.  Follow-up report on the diagnosis of diabetes mellitus. , 2003, Diabetes care.

[56]  J. Kehayias,et al.  Body composition assessment in extreme obesity and after massive weight loss induced by gastric bypass surgery. , 2003, American journal of physiology. Endocrinology and metabolism.

[57]  G. Frühbeck,et al.  Adipose tissue as an endocrine organ: role of leptin and adiponectin in the pathogenesis of cardiovascular diseases , 2003, Journal of Physiology and Biochemistry.

[58]  D. Gigot,et al.  Pre‐B‐cell colony‐enhancing factor, whose expression is up‐regulated in activated lymphocytes, is a nicotinamide phosphoribosyltransferase, a cytosolic enzyme involved in NAD biosynthesis , 2002, European journal of immunology.

[59]  G. Frühbeck,et al.  Rationale for the existence of additional adipostatic hormones , 2001, FASEB journal : official publication of the Federation of American Societies for Experimental Biology.

[60]  I McNiece,et al.  Cloning and characterization of the cDNA encoding a novel human pre-B-cell colony-enhancing factor , 1994, Molecular and cellular biology.

[61]  K. Choi,et al.  Plasma visfatin levels are positively associated with circulating interleukin-6 in apparently healthy Korean women. , 2008, Diabetes research and clinical practice.

[62]  Shyi-Jang Shin,et al.  Elevated plasma level of visfatin/pre-B cell colony-enhancing factor in patients with type 2 diabetes mellitus. , 2006, The Journal of clinical endocrinology and metabolism.

[63]  P. Arner Editorial: Visfatin—A True Or False Trail To Type 2 Diabetes Mellitus , 2006 .