Towards Sleep Apnea Screening with an Under-the-Mattress IR-UWB Radar Using Machine Learning

In this work, we apply machine learning to investigate the effectiveness of an Impulse Radio Ultra-Wide Band (IR-UWB) radar panel, in an under-the-mattress configuration, for detecting apnea events in subjects known to have obstructive sleep apnea (OSA). We consider a collection of features, some novel and some inspired by features that worked well for sleep apnea detection using other types of sensors (i.e., not IR-UWB). To extract the features, we collected a total of 25 hours of data from four subjects as they slept through the night. The data included digitized samples of the IR-UWB radar return signal and the scored polysomnograph (PSG), which is the gold standard and measures a large number of physiological parameters in a well-equipped sleep laboratory. Normal and apnea epochs were extracted from the IR-UWB data corresponding to normal and apnea epochs in the PSG data. Statistical features were derived from these extracted epochs and a Linear Discriminant classifier was trained. Using cross-validation, we found that the classifier had an accuracy of around 70% in detection of apnea and normal epochs. The novel aspect of this project involves processing and investigation of different methods for feature extraction on data obtained from real apnea subjects and suggests that the radar, when paired with other under-the-mattress sensors might provide an effective screening device in a convenient form factor.

[1]  Abdul Ghaaliq Lalkhen,et al.  Clinical tests: sensitivity and specificity , 2008 .

[2]  A. Newman,et al.  Prospective Study of Obstructive Sleep Apnea and Incident Coronary Heart Disease and Heart Failure: The Sleep Heart Health Study , 2010, Circulation.

[3]  Takemi Matsui,et al.  Noncontact screening system with two microwave radars for the diagnosis of sleep apnea-hypopnea syndrome , 2013, 2013 35th Annual International Conference of the IEEE Engineering in Medicine and Biology Society (EMBC).

[4]  Marimuthu Palaniswami,et al.  Support Vector Machines for Automated Recognition of Obstructive Sleep Apnea Syndrome From ECG Recordings , 2009, IEEE Transactions on Information Technology in Biomedicine.

[5]  Cheong Boon Soh,et al.  Wireless Sensing of Human Respiratory Parameters by Low-Power Ultrawideband Impulse Radio Radar , 2011, IEEE Transactions on Instrumentation and Measurement.

[6]  Conor Heneghan,et al.  Automated processing of the single-lead electrocardiogram for the detection of obstructive sleep apnoea , 2003, IEEE Transactions on Biomedical Engineering.

[7]  M. Stone Cross‐Validatory Choice and Assessment of Statistical Predictions , 1976 .

[8]  E. M. Staderini,et al.  UWB radars in medicine , 2002 .

[9]  Jordanna Hostler,et al.  Diagnosis of Obstructive Sleep Apnea in Adults , 2015, Annals of Internal Medicine.

[10]  Mary Ann Weitnauer,et al.  Spectrum-averaged Harmonic Path (SHAPA) algorithm for non-contact vital sign monitoring with ultra-wideband (UWB) radar , 2014, 2014 36th Annual International Conference of the IEEE Engineering in Medicine and Biology Society.

[11]  Brian Caffo,et al.  Prospective Study of Sleep-disordered Breathing and Hypertension the Sleep Heart Health Study at a Glance Commentary , 2022 .

[12]  Ronald M. Aarts,et al.  The acoustics of snoring. , 2010, Sleep medicine reviews.

[13]  David Girbau,et al.  ANALYSIS OF VITAL SIGNS MONITORING USING AN IR-UWB RADAR , 2010 .

[14]  森利·富 Ultra wideband monitoring systems and antennas , 2007 .

[15]  Conor Heneghan,et al.  Assessment of sleep/wake patterns using a non-contact biomotion sensor , 2008, 2008 30th Annual International Conference of the IEEE Engineering in Medicine and Biology Society.

[16]  M. H. Asyali,et al.  Sleep stage and obstructive apneaic epoch classification using single-lead ECG , 2010, Biomedical engineering online.

[17]  Ian T. Jolliffe,et al.  Principal Component Analysis , 2002, International Encyclopedia of Statistical Science.

[18]  Isabelle Guyon,et al.  An Introduction to Variable and Feature Selection , 2003, J. Mach. Learn. Res..

[19]  N. Punjabi The epidemiology of adult obstructive sleep apnea. , 2008, Proceedings of the American Thoracic Society.

[20]  Yoshua Bengio,et al.  Pattern Recognition and Neural Networks , 1995 .

[21]  S. Quan,et al.  Rules for scoring respiratory events in sleep: update of the 2007 AASM Manual for the Scoring of Sleep and Associated Events. Deliberations of the Sleep Apnea Definitions Task Force of the American Academy of Sleep Medicine. , 2012, Journal of clinical sleep medicine : JCSM : official publication of the American Academy of Sleep Medicine.

[22]  Ron Kohavi,et al.  Wrappers for Feature Subset Selection , 1997, Artif. Intell..

[23]  Conor Heneghan,et al.  SleepMinder: An innovative contact-free device for the estimation of the apnoea-hypopnoea index , 2009, 2009 Annual International Conference of the IEEE Engineering in Medicine and Biology Society.

[24]  Yee Siong Lee,et al.  Monitoring and Analysis of Respiratory Patterns Using Microwave Doppler Radar , 2014, IEEE Journal of Translational Engineering in Health and Medicine.