Protein kinase A signaling and calcium ions are major players in PAF mediated toxicity against Aspergillus niger

[1]  Z. Gáspári,et al.  “Invisible” Conformers of an Antifungal Disulfide Protein Revealed by Constrained Cold and Heat Unfolding, CEST-NMR Experiments, and Molecular Dynamics Calculations , 2015, Chemistry.

[2]  G. Goldman,et al.  The Involvement of the Mid1/Cch1/Yvc1 Calcium Channels in Aspergillus fumigatus Virulence , 2014, PloS one.

[3]  U. Sagaram,et al.  Specific domains of plant defensins differentially disrupt colony initiation, cell fusion and calcium homeostasis in Neurospora crassa , 2014, Molecular microbiology.

[4]  S. Thewes.  Calcineurin-Crz1 Signaling in Lower Eukaryotes , 2014, Eukaryotic Cell.

[5]  G. Batta,et al.  Synthesis of PAF, an antifungal protein from P. chrysogenum, by native chemical ligation: native disulfide pattern and fold obtained upon oxidative refolding. , 2013, Chemistry.

[6]  J. Gancedo.  Biological roles of cAMP: variations on a theme in the different kingdoms of life , 2013, Biological reviews of the Cambridge Philosophical Society.

[7]  É. Csősz,et al.  In vivo application of a small molecular weight antifungal protein of Penicillium chrysogenum (PAF). , 2013, Toxicology and applied pharmacology.

[8]  F. Marx,et al.  Antifungal proteins: More than antimicrobials? , 2013, Fungal biology reviews.

[9]  E. Ruelland,et al.  Signal transduction pathways involving phosphatidylinositol 4-phosphate and phosphatidylinositol 4,5-bisphosphate: convergences and divergences among eukaryotic kingdoms. , 2013, Progress in lipid research.

[10]  V. Meyer,et al.  The Aspergillus giganteus antifungal protein AFPNN5353 activates the cell wall integrity pathway and perturbs calcium homeostasis , 2011, BMC Microbiology.

[11]  M. Chu,et al.  The Antifungal Activity of the Penicillium chrysogenum Protein PAF Disrupts Calcium Homeostasis in Neurospora crassa , 2010, Eukaryotic Cell.

[12]  V. Meyer,et al.  The antifungal protein PAF interferes with PKC/MPK and cAMP/PKA signalling of Aspergillus nidulans , 2009, Molecular microbiology.

[13]  B. Sarg,et al.  Functional aspects of the solution structure and dynamics of PAF – a highly‐stable antifungal protein from Penicillium chrysogenum , 2009, The FEBS journal.

[14]  Wei Zhao,et al.  Deletion of the Protein Kinase A Regulatory Subunit Leads to Deregulation of Mitochondrial Activation and Nuclear Duplication in Aspergillus fumigatus , 2009, Eukaryotic Cell.

[15]  C. Grosse,et al.  Protein Kinase A Regulates Growth, Sporulation, and Pigment Formation in Aspergillus fumigatus , 2008, Applied and Environmental Microbiology.

[16]  I. Pócsi,et al.  The Penicillium chrysogenum antifungal protein PAF, a promising tool for the development of new antifungal therapies and fungal cell biology studies , 2008, Cellular and Molecular Life Sciences.

[17]  Christophe d'Enfert,et al.  G-protein and cAMP-mediated signaling in aspergilli: a genomic perspective. , 2006, Fungal genetics and biology : FG & B.

[18]  Jae-Hyuk Yu,et al.  The pkaB Gene Encoding the Secondary Protein Kinase A Catalytic Subunit Has a Synthetic Lethal Interaction with pkaA and Plays Overlapping and Opposite Roles in Aspergillus nidulans , 2005, Eukaryotic Cell.

[19]  L. Csernoch,et al.  Antifungal Protein PAF Severely Affects the Integrity of the Plasma Membrane of Aspergillus nidulans and Induces an Apoptosis-Like Phenotype , 2005, Antimicrobial Agents and Chemotherapy.

[20]  N. Read,et al.  Cross‐talk between cAMP and calcium signalling in Aspergillus niger , 2005, Molecular microbiology.

[21]  G. Szigeti,et al.  The Penicillium chrysogenum-derived antifungal peptide shows no toxic effects on mammalian cells in the intended therapeutic concentration , 2005, Naunyn-Schmiedeberg's Archives of Pharmacology.

[22]  A. Collis,et al.  Calcium measurement in living filamentous fungi expressing codon‐optimized aequorin , 2004, Molecular microbiology.

[23]  F. Marx.  Small, basic antifungal proteins secreted from filamentous ascomycetes: a comparative study regarding expression, structure, function and potential application , 2004, Applied Microbiology and Biotechnology.

[24]  M. Benčina,et al.  Lipid composition of cAMP-dependent protein kinase mutants of Aspergillus niger. , 2003, FEMS microbiology letters.

[25]  W. Burgstaller,et al.  Characterization of the Penicillium chrysogenum antifungal protein PAF , 2003, Archives of Microbiology.

[26]  J. Visser,et al.  Cyclic AMP-dependent protein kinase is involved in morphogenesis of Aspergillus niger. , 2002, Microbiology.

[27]  L S Robertson,et al.  The yeast A kinases differentially regulate iron uptake and respiratory function. , 2000, Proceedings of the National Academy of Sciences of the United States of America.

[28]  John C. Lindon,et al.  Improved WATERGATE Pulse Sequences for Solvent Suppression in NMR Spectroscopy , 1998 .

[29]  V. Saudek,et al.  Gradient-tailored excitation for single-quantum NMR spectroscopy of aqueous solutions , 1992, Journal of biomolecular NMR.