Electronic Tongues–A Review

Sensing technologies for objective evaluation such as the discrimination and quantification of tastes have been developed since around 1990, before the discovery of taste receptors. Electronic tongues aim to discriminate and analyze foods and beverages and are well known as sensing technologies that greatly contribute to quality management. A taste sensor, i.e., an electronic tongue with global selectivity, is developed to realize a sensor that responds to taste chemical substances and can be used to quantify the type of taste focusing on the fact that humans discriminate the taste of foods and beverages on the tongue with the five basic tastes. In this paper, we focus on the taste sensor and describe its sensing principle, its difference from general electronic tongues that do not aim to quantify tastes, examples of its use, and the recent trend of research of electronic tongues.

[1]  Akihiro Ikeda,et al.  Development of a Portable Taste Sensor with a Lipid/Polymer Membrane , 2013, Sensors.

[2]  Kiyoshi Toko,et al.  Flavor evaluation using taste sensor for UHT processed milk stored in cartons having different light permeabilities. , 2009 .

[3]  Fredrik Winquist,et al.  Voltammetric electronic tongues – basic principles and applications , 2008 .

[4]  Alisa Rudnitskaya,et al.  Cross-sensitivity evaluation of chemical sensors for electronic tongue: determination of heavy metal ions , 1997 .

[5]  Qingjun Liu,et al.  Bioelectronic tongue of taste buds on microelectrode array for salt sensing. , 2013, Biosensors & bioelectronics.

[6]  C. Di Natale,et al.  The features of the electronic tongue in comparison with the characteristics of the discrete ion-selective sensors , 1999 .

[7]  M. Behrens,et al.  The molecular receptive ranges of human TAS2R bitter taste receptors. , 2010, Chemical senses.

[8]  Qingjun Liu,et al.  Extracellular potentials recording in intact olfactory epithelium by microelectrode array for a bioelectronic nose. , 2010, Biosensors & bioelectronics.

[9]  Wolfgang Göpel,et al.  Characterisation of food freshness with sensor arrays , 1994 .

[10]  N. Ryba,et al.  Mammalian Sweet Taste Receptors , 2001, Cell.

[11]  Roberto Paolesse,et al.  Metalloporphyrin - Based Electronic Tongue: an Application for the Analysis of Italian White Wines , 2007, Sensors.

[12]  K. Toko,et al.  Quantification of suppression of bitterness using an electronic tongue. , 2001, Journal of pharmaceutical sciences.

[13]  K. Hayashi,et al.  Multichannel taste sensor using lipid membranes , 1990 .

[14]  B. Trivedi,et al.  Gustatory system: The finer points of taste , 2012, Nature.

[15]  Lihua Geng,et al.  Determination of Ginseng with Different Ages Using a Taste-Sensing System , 2013 .

[16]  Jayaram Chandrashekar,et al.  The cells and logic for mammalian sour taste detection , 2006, Nature.

[17]  Kiyoshi Toko,et al.  Development of Sensor with High Selectivity for Saltiness and Its Application in Taste Evaluation of Table Salt , 2010 .

[18]  V. Anand,et al.  The latest trends in the taste assessment of pharmaceuticals. , 2007, Drug discovery today.

[19]  Jayaram Chandrashekar,et al.  The cells and peripheral representation of sodium taste in mice , 2010, Nature.

[20]  Jayaram Chandrashekar,et al.  An amino-acid taste receptor , 2002, Nature.

[21]  Kiyoshi Toko.  Biomimetic Sensor Technology by Kiyoshi Toko , 2000 .

[22]  C. Natale,et al.  Evaluation of Italian wine by the electronic tongue: recognition, quantitative analysis and correlation with human sensory perception , 2003 .

[23]  Julian W. Gardner,et al.  Sensors and Sensory Systems for an Electronic Nose , 1992 .

[24]  Kiyoshi Toko,et al.  Development of an Artificial Lipid-Based Membrane Sensor with High Selectivity and Sensitivity to the Bitterness of Drugs and with High Correlation with Sensory Score , 2009 .

[25]  Kiyoshi Toko,et al.  Biomimetic Sensor Technology , 2000 .

[26]  R. Margolskee,et al.  T1R3 and gustducin in gut sense sugars to regulate expression of Na+-glucose cotransporter 1 , 2007, Proceedings of the National Academy of Sciences.

[27]  Antonella Macagnano,et al.  Electronic nose and electronic tongue integration for improved classification of clinical and food samples , 2000 .

[28]  Takamichi Nakamoto,et al.  Human Olfactory Displays and Interfaces: Odor Sensing and Presentation , 2012 .

[29]  H. Ikezaki,et al.  Evaluation of the umami taste intensity of green tea by a taste sensor. , 2008, Journal of agricultural and food chemistry.

[30]  I. Lundström,et al.  A voltammetric electronic tongue. , 2005, Chemical senses.

[31]  H. Troy Nagle,et al.  Handbook of Machine Olfaction: Electronic Nose Technology , 2003 .

[32]  Gary J. Pickering,et al.  Astringency: Mechanisms and Perception , 2008, Critical reviews in food science and nutrition.

[33]  Nobuyuki Hayashi,et al.  Evaluation of the Astringency of Black Tea by a Taste Sensor System: Scope and Limitation , 2007, Bioscience, biotechnology, and biochemistry.

[34]  P. Kleinebudde,et al.  A comparative study on two electronic tongues for pharmaceutical formulation development. , 2011, Journal of pharmaceutical and biomedical analysis.

[35]  N. Ryba,et al.  T2Rs Function as Bitter Taste Receptors , 2000, Cell.

[36]  Ingemar Lundström,et al.  Electronic Tongues and Combinations of Artificial Senses , 2002 .

[37]  Neil Savage,et al.  Technology: The taste of things to come , 2012, Nature.

[38]  Kiyoshi Toko,et al.  Taste sensor with global selectivity , 1996 .

[39]  Mitsuyoshi Okamoto,et al.  Bitterness evaluation of orally disintegrating famotidine tablets using a taste sensor , 2009 .

[40]  Jayaram Chandrashekar,et al.  A Novel Family of Mammalian Taste Receptors , 2000, Cell.

[41]  K. Persaud,et al.  Analysis of discrimination mechanisms in the mammalian olfactory system using a model nose , 1982, Nature.

[42]  K. Toko,et al.  Taste sensor. , 2005, Chemical senses.

[43]  Hiroshi Okadome,et al.  Analysis of the tastes of brown rice and milled rice with different milling yields using a taste sensing system , 2004 .

[44]  I. Lundström,et al.  A hybrid electronic tongue. , 2000 .

[45]  Kiyoshi Toko,et al.  Relationship between Taste Sensor Response and Amount of Quinine Adsorbed on Lipid/Polymer Membrane , 2012 .

[46]  Mahdi Ghasemi-Varnamkhasti,et al.  Biomimetic-based odor and taste sensing systems to food quality and safety characterization: An overview on basic principles and recent achievements , 2010 .

[47]  N. Ryba,et al.  The receptors and cells for mammalian taste , 2006, Nature.

[48]  Fabrizio Davide,et al.  Tasting of beverages using an electronic tongue , 1997 .

[49]  Kiyoshi Toko,et al.  Simple Screening Method for Pesticide Residues by Detecting Coexistent Adjuvants Using Potentiometric Measurement , 2012 .

[50]  Ping Wang,et al.  A biomimetic taste receptor cell-based biosensor for electrophysiology recording and acidic sensation , 2009 .

[51]  Yusuke Amino,et al.  Involvement of the Calcium-sensing Receptor in Human Taste Perception , 2009, The Journal of Biological Chemistry.

[52]  Kenneth S Suslick,et al.  A colorimetric sensor array for organics in water. , 2005, Journal of the American Chemical Society.

[53]  Y. Ueda,et al.  Flavor characteristics of glutathione in raw and cooked foodstuffs. , 1997, Bioscience, biotechnology, and biochemistry.

[54]  Kiyoshi Toko,et al.  Study of sweet taste evaluation using taste sensor with lipid/polymer membranes. , 2004, Biosensors & bioelectronics.

[55]  N. Bârsan,et al.  Electronic nose: current status and future trends. , 2008, Chemical reviews.

[56]  Kentaro Abe,et al.  Sweetness Sensor with Lipid/Polymer Membranes : Response to Various Sugars , 2011 .

[57]  Y. Vlasov,et al.  Chalcogenide glass chemical sensors: Research and analytical applications. , 1994, Talanta.

[58]  Takahiro Uchida,et al.  A new method for evaluating the bitterness of medicines in development using a taste sensor and a disintegration testing apparatus. , 2010, Chemical & pharmaceutical bulletin.

[59]  Akihiro Ikeda,et al.  Development and Evaluation of a Miniaturized Taste Sensor Chip , 2011, Sensors.

[60]  K. Suslick,et al.  Colorimetric sensor arrays for the analysis of beers: a feasibility study. , 2006, Journal of agricultural and food chemistry.

[61]  Ingemar Lundström,et al.  The combination of an electronic tongue and an electronic nose , 1999 .

[62]  Daniel Citterio,et al.  Smart taste sensors. , 2008, Analytical chemistry.

[63]  C. Di Natale,et al.  Nonspecific sensor arrays ("electronic tongue") for chemical analysis of liquids (IUPAC Technical Report) , 2005 .

[64]  I. Lundström,et al.  An electronic tongue based on voltammetry , 1997 .

[65]  Toyosaka Moriizumi,et al.  Gas identification using micro gas sensor array and neural-network pattern recognition , 1996 .

[66]  Peter Kleinebudde,et al.  Taste sensing systems (electronic tongues) for pharmaceutical applications. , 2011, International journal of pharmaceutics.

[67]  Chen Zhang,et al.  Colorimetric sensor array for soft drink analysis. , 2007, Journal of agricultural and food chemistry.

[68]  Kiyoshi Toko,et al.  Quantification of tastes of amino acids using taste sensors , 2013 .

[69]  Antonio Riul,et al.  Recent advances in electronic tongues. , 2010, The Analyst.

[70]  Kiyoshi Toko,et al.  Advanced Taste Sensors Based on Artificial Lipids with Global Selectivity to Basic Taste Qualities and High Correlation to Sensory Scores , 2010, Sensors.

[71]  Patrycja Ciosek,et al.  Sensor arrays for liquid sensing--electronic tongue systems. , 2007, The Analyst.

[72]  Kentaro Abe,et al.  Sweetness Sensor with Lipid/Polymer Membranes : Sweet-Responsive Substances , 2011 .

[73]  Hitoshi Inada,et al.  Transient receptor potential family members PKD1L3 and PKD2L1 form a candidate sour taste receptor , 2006, Proceedings of the National Academy of Sciences.

[74]  Keiichi Motoyama,et al.  Reduction of bitterness of antihistaminic drugs by complexation with β-cyclodextrins. , 2011, Journal of pharmaceutical sciences.