Characteristics of Peripheral and Peritoneal Lymphocytes from Continuous Ambulatory Peritoneal Dialysis Patients

The role of peritoneal lymphocytes in host immunity for continuous ambulatory peritoneal dialysis (CAPD) patients Is just beginning to be understood. CAPD therapy Increases the proportion of peritoneal lymphocytes, most of which demonstrate signs of activation. There are decreased peritoneal T cells and increased peritoneal B cells as compared to the patients’ peripheral blood. When studies examine Immunophenotypes of peripheral and peritoneallymphocytes over time, no significant changes are found. Although changes in peritoneal lymphocyte subsets occur during peritonitis episodes, there are no changes In peripheral blood lymphocytes. The purpose of this article Is to provide a brief review of research that has studied lymphocytes In CAPD patients.

[1]  M. Leffell,et al.  Chronic T-Lymphocyte Activation in Chronic Renal Failure: A Study of Hemodialysis, Capd and Pre-Dialysis Patients , 1992, The International journal of artificial organs.

[2]  G. Malatesta,et al.  Multiple sclerosis: an immune system activation disease. , 1991, Acta neurologica.

[3]  R. Krediet,et al.  The Mesothelial Cells in CAPD Effluent and Their Relation to Peritonitis Incidence , 1991, Peritoneal dialysis international : journal of the International Society for Peritoneal Dialysis.

[4]  S. Raziuddin,et al.  Immune activation and T cell subset abnormalities in circulation of patients with recently diagnosed type I diabetes mellitus , 1990, Clinical and experimental immunology.

[5]  S. Lewis,et al.  Comparison of peritoneal white blood cell parameters from continuous ambulatory peritoneal dialysis patients with a high or low incidence of peritonitis. , 1990, American journal of kidney diseases : the official journal of the National Kidney Foundation.

[6]  F. Port.  Mortality and causes of death in patients with end-stage renal failure. , 1990, American journal of kidney diseases : the official journal of the National Kidney Foundation.

[7]  S. Davies.  Peritoneal lymphocyte populations in CAPD patients. , 1990, Contributions to nephrology.

[8]  P. Giordano,et al.  Analysis of cellular populations in peritoneal effluents of children on CAPD. , 1989, Clinical nephrology.

[9]  S. Davies,et al.  Activation of immunocompetent cells in the peritoneum of patients treated with CAPD. , 1989, Kidney international.

[10]  J. Briggs,et al.  Longitudinal Study of Peritoneal Defence Mechanisms in Patients on Continuous Ambulatory Peritoneal Dialysis (CAPD) , 1989, Peritoneal dialysis international : journal of the International Society for Peritoneal Dialysis.

[11]  D. Adu,et al.  T-cell-independent and T-cell-dependent antibody responses in patients with chronic renal failure. , 1989, Nephrology, dialysis, transplantation : official publication of the European Dialysis and Transplant Association - European Renal Association.

[12]  B. Brando,et al.  Flow cytometric study of immunocompetent cell phenotypes and phagocytosis in CAPD effluent. , 1988, ASAIO transactions.

[13]  S. Carozzi,et al.  Interferon-γ (IFN-γ) as In Vitro Enhancing Factor of Peritoneal Macrophage Defective Bactericidal Activity During Continuous Ambulatory Peritoneal Dialysis (CAPD) , 1988 .

[14]  H. J. Bos,et al.  Distinct Subpopulations of Elicited Human Macrophages in Peritoneal Dialysis Patients and Women Undergoing Laparoscopy: A Study on Peroxidatic Activity , 1988, Journal of leukocyte biology.

[15]  T. Huang,et al.  Serial cell-mediated immunological changes in terminal uremic patients on continuous ambulatory peritoneal dialysis therapy. , 1988, American journal of nephrology.

[16]  D. Han,et al.  Studies on lymphocyte subpopulations and cell-mediated immunity in patients with chronic renal failure. , 1988, Yonsei medical journal.

[17]  W. Weimar,et al.  Intact humoral immune response in patients on continuous ambulatory peritoneal dialysis. , 1988, Nephron.

[18]  J. Briggs,et al.  In vitro analysis of B lymphocyte function in uraemia. , 1987, Clinical and experimental immunology.

[19]  N. Letvin,et al.  A defect of immunoregulatory T cell subsets in systemic lupus erythematosus patients demonstrated with anti-2H4 antibody. , 1987, The Journal of clinical investigation.

[20]  J. Briggs,et al.  Bactericidal activity of peritoneal macrophages from continuous ambulatory dialysis patients. , 1987, Nephrology, dialysis, transplantation : official publication of the European Dialysis and Transplant Association - European Renal Association.

[21]  G. Boner,et al.  Cell-mediated immunity in uremic patients prior to and after 6 months' treatment with continuous ambulatory peritoneal dialysis. , 1986, Israel journal of medical sciences.

[22]  K. Meyer zum Büschenfelde,et al.  Impaired cellular immune responses in chronic renal failure: evidence for a T cell defect. , 1986, Kidney international.

[23]  V. Debari,et al.  Surface Marker Characterization of Peritoneal Dialysis Patients’ Intraperitoneal Leukocytes by Monoclonal Antibodies , 1986 .

[24]  E. Langhoff,et al.  Effect of interleukin-2 and methylprednisolone on in vitro transformation of uremic lymphocytes. , 1986, International archives of allergy and applied immunology.

[25]  J. Young,et al.  Nutrition and delayed hypersensitivity during continuous ambulatory peritoneal dialysis in relation to peritonitis. , 1986, Nephron.

[26]  W. Keane,et al.  Antimicrobial activities of dialysate-elicited and resident human peritoneal macrophages , 1985, Infection and immunity.

[27]  G. Piccoli,et al.  Association between human lymphocyte antigens B8, DR3 and response to peritonitis in patients undergoing continuous ambulatory peritoneal dialysis. , 1985, Nephron.

[28]  E. Neilson,et al.  Analysis of peritoneal macrophages in continuous ambulatory peritoneal dialysis patients. , 1984, Kidney international.

[29]  M. Formica,et al.  Improved Cell-Mediated Immunity in CAPD Patients as Compared to those on Hemodialysis , 1984 .

[30]  G. Piccoli,et al.  Lymphocyte Subsets Assayed by Numerical Tests in CAPD , 1984, The International journal of artificial organs.

[31]  W. Keane,et al.  Peritoneal macrophages and opsonins: antibacterial defense in patients undergoing chronic peritoneal dialysis. , 1983, The Journal of infectious diseases.

[32]  M. Zembala,et al.  Output of Peritoneal Cells into Peritoneal Dialysate , 1983 .

[33]  E. Langhoff,et al.  Improved lymphocyte transformation in vitro of patients on continuous ambulatory peritoneal dialysis. , 1983, Proceedings of the European Dialysis and Transplant Association. European Dialysis and Transplant Association.

[34]  D. De Francesco,et al.  Continuous ambulatory peritoneal dialysis and cellular immunity. , 1983, Proceedings of the European Dialysis and Transplant Association. European Dialysis and Transplant Association.

[35]  A. Pesce,et al.  Preliminary observations on the laboratory markers of cell-mediated immunity in patients transferring from hemodialysis to continuous ambulatory peritoneal dialysis. , 1983, Contributions to nephrology.

[36]  G. Piccoli,et al.  Continuous ambulatory peritoneal dialysis improves immunodeficiency in uremic patients. , 1983, Nephron.

[37]  R. Coppo,et al.  The Influence of Peritoneal Dialysis on Cellular Immunity , 1981 .

[38]  V. Farewell,et al.  High incidence of neoplasia in uremic patients receiving long-term dialysis. Cancer and long-term dialysis. , 1981, Nephron.

[39]  R. Ganguly,et al.  Studies of human peritoneal cells: a normal saline lavage technique for the isolation and characterization of cells from peritoneal dialysis patients. , 1980, Journal of the Reticuloendothelial Society.

[40]  E. Lustbader,et al.  Host responses to hepatitis B infection in patients in a chronic hemodialysis unit. , 1977, Kidney international.

[41]  G. A. Sutherland,et al.  Increased incidence of malignancy in chronic renal failure. , 1977, Nephron.

[42]  A. Pasternack,et al.  Skin test sensitivity and antigen-induced lymphocyte transformation in uraemia. , 1973, Clinical and experimental immunology.

[43]  J. Mannick,et al.  Renal transplantation in azotemic dogs. , 1960, Surgery.