Transplantation of tectal tissue in rats. II. Distribution of host neurons which project to transplants

Tectal tissue was dissected from fetal rats and transplanted adjacent to the superior colliculus of newborn rats. The recipient animals were then allowed to survive for 6 or more weeks. Subsequent examination revealed that the transplants generally lay over the host inferior colliculus and rostral part of the cerebellum and had substantial fiber connections with the host superior colliculus. To determine which host areas projected to the transplants, horseradish peroxidase (HRP) was injected into the transplants, and the host brain was examined for the presence of retrogradely filled neurons.

[1]  A. Harvey,et al.  Transplantation of tectal tissue in rats. I. Organization of transplants and pattern of distribution of host afferents within them , 1981, The Journal of comparative neurology.

[2]  R. Lund,et al.  The distribution of the callosal projection to the occipital visual cortex in rats and mice , 1981, Brain Research.

[3]  R. Lund,et al.  Transplantation of embryonic occipital cortex to the tectal region of newborn rats: A light microscopic study of organization and connectivity of the transplants , 1980, The Journal of comparative neurology.

[4]  P. Graziadei,et al.  Regrowth of olfactory sensory axons into transplanted neural tissue. 1. Development of connections with the occipital cortex , 1980, Brain Research.

[5]  N. Mangini,et al.  Retinotopic organization of striate and extrastriate visual cortex in the mouse , 1980, The Journal of comparative neurology.

[6]  G. D. Das,et al.  Heterotopic neural transplants in the cerebellum of the rat: their afferents , 1980, Brain Research.

[7]  G. D. Das,et al.  Neocortical transplants in the cerebellum of the rat: their afferents and efferents , 1980, Brain Research.

[8]  W. Nauta,et al.  Efferent connections of the substantia nigra and ventral tegmental area in the rat , 1979, Brain Research.

[9]  F. Scalia,et al.  Topographic organization of the projections of the retina to the pretectal region in the rat , 1979, The Journal of comparative neurology.

[10]  C. Legg,et al.  An autoradiographic study of the efferent projections of the ventral lateral geniculate nucleus of the hooded rat , 1979, Brain Research.

[11]  E. Kawana,et al.  Efferent projections of the parabigeminal nucleus in rats: A horseradish peroxidase (HRP) study , 1979, Brain Research.

[12]  J. Pujol,et al.  The efferent connections of the nucleus raphe centralis superior in the rat as revealed by radioautography , 1979, Brain Research.

[13]  H. Holländer,et al.  An autoradiographic study of the subcortical projections of the rabbit striate cortex in the adult and during postnatal development , 1979, The Journal of comparative neurology.

[14]  B. Stein,et al.  Sources of subcortical projections to the superior colliculus in the cat , 1979, The Journal of comparative neurology.

[15]  J. Adams Ascending projections to the inferior colliculus , 1979, The Journal of comparative neurology.

[16]  B. Beyerl Afferent projections to the central nucleus of the inferior colliculus in the rat , 1978, Brain Research.

[17]  M. Mesulam,et al.  Tetramethyl benzidine for horseradish peroxidase neurohistochemistry: a non-carcinogenic blue reaction product with superior sensitivity for visualizing neural afferents and efferents. , 1978, The journal of histochemistry and cytochemistry : official journal of the Histochemistry Society.

[18]  H. Vanegas,et al.  Early stages of uptake and transport of horseradish‐peroxidase by cortical structures, and its use for the study of local neurons and their processes , 1978, The Journal of comparative neurology.

[19]  C. Blakemore,et al.  Functional organization in the visual cortex of the golden hamster , 1976, The Journal of comparative neurology.

[20]  R. Lund,et al.  Transplanted neural tissue develops connections with host rat brain. , 1976, Science.

[21]  L. Swanson The locus coeruleus: A cytoarchitectonic, golgi and immunohistochemical study in the albino rat , 1976, Brain Research.

[22]  R. Lund,et al.  Prenatal development of central optic pathways in albino rats , 1976, The Journal of comparative neurology.

[23]  J. Lund,et al.  Monkey retinal ganglion cells: Morphometric analysis and tracing of axonal projections, with a consideration of the peroxidase technique , 1975, The Journal of comparative neurology.

[24]  V. Caviness Architectonic map of neocortex of the normal mouse , 1975, The Journal of comparative neurology.

[25]  C. Gilbert,et al.  The projections of cells in different layers of the cat's visual cortex , 1975, The Journal of comparative neurology.

[26]  P C Letourneau,et al.  Cell-to-substratum adhesion and guidance of axonal elongation. , 1975, Developmental biology.

[27]  U. Dräger,et al.  Receptive fields of single cells and topography in mouse visual cortex , 1975, The Journal of comparative neurology.

[28]  V. Montero,et al.  Retinotopic organization of striate and peristriate visual cortex in the albino rat. , 1973, Brain research.

[29]  F. Scalia The termination of retinal axons in the pretectal region of mammals , 1972, The Journal of comparative neurology.

[30]  S. Strich ATLAS OF THE MOUSE BRAIN AND SPINAL CORD , 1972 .

[31]  R. Sperry CHEMOAFFINITY IN THE ORDERLY GROWTH OF NERVE FIBER PATTERNS AND CONNECTIONS. , 1963, Proceedings of the National Academy of Sciences of the United States of America.

[32]  W. Krieg Connections of the cerebral cortex. I. The albino rat. A. Topography of the cortical areas , 1946 .

[33]  P. Weiss In vitro experiments on the factors determining the course of the outgrowing nerve fiber , 1934 .

[34]  A. Harvey,et al.  TRANSPLANTATION OF EMBRYONIC NEURAL TISSUE TO THE TECTAL REGION OF NEWBORN RATS , 1982 .

[35]  K Zilles,et al.  A quantitative approach to cytoarchitectonics. VI. The areal pattern of the cortex of the albino rat. , 1980, Anatomy and embryology.

[36]  T. J. Horder,et al.  The Nature of the Nerve Fibre Guidance Mechanism Responsible for the Formation of an Orderly Central Visual Projection , 1979 .

[37]  R. Lund The occipitotectal pathway of the rat. , 1966, Journal of anatomy.