Correlation of Clinical, Radiological and Histopathological Diagnosis among Patients with Sinonasal Masses

Introduction: Neoplasms of the sinuses and nasal cavity account for 0.2–0.8 % of all carcinomas. The present study was carried out to find out correlation of clinical, radiological and histopathological diagnosis of sinonasal masses. Material and Methods: The present study was carried out on 60 patients of any age and sex randomly selected who presented with sinonasal masses in the department of Otorhinolaryngology and Pathology in Guru Gobind Singh Medical College and Hospital, Faridkot. These cases were subjected to routine hematological and biochemical evaluation, nasal endoscopy, xray paranasal sinuses/ CT scan and biopsy. Tissues were routinely processed for histopathological sections of 5 micron thickness and were stained by hematoxylin and eosin stain. Special staining by reticulin, von gieson, PAS and masson’strichrome were undertaken whenever applicable. The data so obtained was compiled, analyzed and valid conclusion drawn. Results: In present study, histopathology showed the maximum cases (42 cases) of inflammatory polyps. On the basis of radiology, out of 60 patients, 43 patients (71.66%) were non-neoplastic, 10 patients (16.66%) were benign and 7 patients (11.66%) were malignant. In all the 60 patients, clinical diagnosis correlated with the radiologic Histopathological examination (HPE) report made the clinical diagnosis in 6 (10%) patients in which clinically inconclusive diagnosis of unilateral sinonasal mass was made and in 54 patients (90%) clinical and HPE diagnosis was same. All 6 patients had clinically inconclusive diagnosis of unilateral sinonasal mass, all of which were reported after HPE, 1 case ameloblastoma of maxilla, 1 case inverted papilloma, 1 case rhinoscleroma, 2 cases round cell tumour, in 2 cases immunohistochemistry confirmed as extramedullaryplasmacytoma and esthesioneuroblastoma. Conclusion: Comparison of histopathological findings with clinical findings showed that, a careful histopathological examination (HPE) is necessary to analyze the specific type of a lesion. Thus, HPE of the removed tissue is mandatory to provide the actual diagnosis of the various conditions identified as a sinonasal mass.